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Table 3 Univariate and multivariate logistic regression analysis of pregnancy outcomes across different maternal age groups (N = 63,137)

From: Age-specific effects on adverse pregnancy outcomes vary by maternal characteristics: a population-based retrospective study in Xiamen, China

Pregnancy outcomes

 

Maternal age (years)

P trend value

< 25

25–29

30–34

≥ 35

GDM*

Crude OR (95%CI)

0.604 (0.560 to 0.651)

Reference

1.774 (1.690 to 1.862)

3.207 (3.010 to 3.417)

< 0.001

 

Adjusted OR (95%CI)

0.615 (0.529 to 0.715)

Reference

1.735 (1.586 to 1.899)

2.705 (2.405 to 3.043)

< 0.001

Hypertension†

Crude OR (95%CI)

0.739 (0.384 to 1.424)

Reference

1.721 (1.134 to 2.612)

4.194 (2.710 to 6.489)

< 0.001

 

Adjusted OR (95%CI)

0.926 (0.399 to 2.150)

Reference

1.717 (0.975 to 3.022)

3.666 (1.923 to 6.988)

< 0.001

Cesarean‡

Crude OR (95%CI)

0.693 (0.658 to 0.731)

Reference

1.697 (1.631 to 1.765)

2.854 (2.693 to 3.024)

< 0.001

 

Adjusted OR (95%CI)

0.692 (0.625 to 0.768)

Reference

1.550 (1.442 to 1.666)

2.282 (2.057 to 2.533)

< 0.001

Preterm birth‡

Crude OR (95%CI)

0.941 (0.842 to 1.050)

Reference

1.215 (1.115 to 1.324)

1.551 (1.382 to 1.741)

< 0.001

 

Adjusted OR (95%CI)

1.017 (0.829 to 1.247)

Reference

1.170 (1.003 to 1.366)

1.568 (1.279 to 1.922)

< 0.001

LBW‡

Crude OR (95%CI)

1.016 (0.912 to 1.131)

Reference

1.179 (1.080 to 1.286)

1.354 (1.198 to 1.530)

< 0.001

 

Adjusted OR (95%CI)

1.003 (0.813 to 1.237)

Reference

1.444 (1.233 to 1.692)

1.940 (1.566 to 2.404)

< 0.001

SGA‡

Crude OR (95%CI)

1.039 (0.932 to 1.157)

Reference

0.862 (0.783 to 0.950)

0.800 (0.689 to 0.930)

< 0.001

 

Adjusted OR (95%CI)

1.058 (0.862 to 1.299)

Reference

1.070 (0.895 to 1.280)

1.082 (0.818 to 1.431)

0.850

LGA‡

Crude OR (95%CI)

0.833 (0.780 to 0.889)

Reference

1.367 (1.301 to 1.436)

1.601 (1.493 to 1.716)

< 0.001

 

Adjusted OR (95%CI)

1.046 (0.923 to 1.185)

Reference

1.067 (0.975 to 1.169)

1.087 (0.958 to 1.233)

0.425

Macrosomia‡

Crude OR (95%CI)

0.885 (0.774 to 1.012)

Reference

1.113 (1.002 to 1.237)

1.228 (1.057 to 1.427)

0.001

 

Adjusted OR (95%CI)

0.998 (0.779 to 1.277)

Reference

0.815 (0.677 to 0.981)

0.652 (0.494 to 0.859)

0.010

Stillbirth‡

Crude OR (95%CI)

1.060 (0.947 to 1.188)

Reference

0.812 (0.731 to 0.901)

0.680 (0.573 to 0.806)

< 0.001

 

Adjusted OR (95%CI)

1.120 (0.903 to 1.390)

Reference

1.091 (0.900 to 1.323)

0.933 (0.676 to 1.287)

0.557

Apgar score < 7‡

Crude OR (95%CI)

1.675 (0.878 to 3.195)

Reference

1.715 (0.983 to 2.992)

0.424 (0.101 to 1.783)

0.071

 

Adjusted OR (95%CI)

2.554 (0.786 to 8.298)

Reference

1.921 (0.644 to 5.729)

1.498 (0.285 to 7.889)

0.423

  1. GDM, gestational diabetes mellitus; LBW, low birth weight; SGA, small-for-gestational-age; LGA, large-for-gestational-age; OR, odds ratio; CI, confidence interval. * was adjusted for systolic blood pressure, pre-pregnancy BMI, education, infant sex, and parity. † was adjusted for GDM, pre-pregnancy BMI, education, infant sex, and parity. ‡ was additionally adjusted for systolic blood pressure above †
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BMC Public Health

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