Table 2 Percentage of excess risk mediated in COVID-19-related outcomes in ethnic minority groups (QResearch cohort)

Minimal adjustment

1.19

0.96

1.47

...

...

...

Household and social factors

1.08

0.87

1.33

57.9

-73.7

168.4

Comorbidities

1.11

0.90

1.37

42.1

-94.7

152.6

Lifestyle and BMI

1.22

0.98

1.50

...

...

...

Maximal adjustment

1.07

0.87

1.33

63.2

-73.7

168.4

Minimal adjustment

1.83

1.63

2.06

...

...

...

Household and social factors

1.65

1.47

1.86

21.7

-3.6

43.4

Comorbidities

1.78

1.58

1.99

6.0

-19.3

30.1

Lifestyle and BMI

1.87

1.67

2.10

...

...

...

Maximal adjustment

1.68

1.49

1.88

18.1

-6.0

41.0

Minimal adjustment

2.58

2.00

3.32

...

...

...

Household and social factors

2.33

1.80

3.01

15.8

-27.2

49.4

Comorbidities

2.41

1.86

3.11

10.8

-33.5

45.6

Lifestyle and BMI

2.68

2.07

3.45

...

...

...

Maximal adjustment

2.35

1.82

3.04

14.6

-29.1

48.1

COVID-19-related death

HR

PERM

Minimal adjustment

1.56

1.40

1.74

...

...

...

Household and social factors

1.32

1.18

1.48

42.9

14.3

67.9

Comorbidities

1.41

1.27

1.58

26.8

-3.6

51.8

Lifestyle and BMI

1.64

1.47

1.83

...

...

...

Maximal adjustment

1.32

1.17

1.48

42.9

14.3

69.6

Minimal adjustment

2.08

1.96

2.22

...

...

...

Household and social factors

1.82

1.71

1.93

24.1

13.9

34.3

Comorbidities

1.87

1.75

1.99

19.4

8.3

30.6

Lifestyle and BMI

2.22

2.08

2.36

...

...

...

Maximal adjustment

1.78

1.66

1.90

27.8

16.7

38.9

Minimal adjustment

2.82

2.47

3.23

...

...

...

Household and social factors

2.52

2.21

2.87

16.5

-2.7

33.5

Comorbidities

2.25

1.95

2.58

31.3

13.2

47.8

Lifestyle and BMI

3.14

2.75

3.60

...

...

...

Maximal adjustment

2.38

2.07

2.73

24.2

4.9

41.2

COVID-19-related death

HR

PERM

Minimal adjustment

1.71

1.54

1.90

...

...

...

Household and social factors

1.41

1.27

1.56

42.3

21.1

62.0

Comorbidities

1.55

1.39

1.72

22.5

-1.4

45.1

Lifestyle and BMI

1.78

1.60

1.98

...

...

...

Maximal adjustment

1.43

1.28

1.59

39.4

16.9

60.6

Minimal adjustment

2.20

2.06

2.34

...

...

...

Household and social factors

1.83

1.72

1.94

30.8

21.7

40.0

Comorbidities

2.06

1.93

2.19

11.7

0.8

22.5

Lifestyle and BMI

2.10

1.97

2.24

8.3

-3.3

19.2

Maximal adjustment

1.75

1.65

1.86

37.5

28.3

45.8

Minimal adjustment

2.95

2.59

3.35

...

...

...

Household and social factors

2.49

2.19

2.84

23.6

5.6

39.0

Comorbidities

2.57

2.25

2.94

19.5

0.5

35.9

Lifestyle and BMI

2.71

2.38

3.10

12.3

-7.7

29.2

Maximal adjustment

2.19

1.91

2.52

39.0

22.1

53.3

COVID-19-related death

HR

PERM

Minimal adjustment

1.13

0.98

1.31

...

...

...

Household and social factors

1.03

0.89

1.19

76.9

-46.2

184.6

Comorbidities

1.20

1.03

1.39

...

...

...

Lifestyle and BMI

1.18

1.01

1.37

...

...

...

Maximal adjustment

1.14

0.99

1.33

...

...

...

Minimal adjustment

1.68

1.56

1.81

...

...

...

Household and social factors

1.51

1.40

1.63

25.0

7.4

41.2

Comorbidities

1.75

1.62

1.89

...

...

...

Lifestyle and BMI

1.85

1.71

1.99

...

...

...

Maximal adjustment

1.71

1.59

1.85

...

...

...

Minimal adjustment

2.54

2.16

2.98

...

...

...

Household and social factors

2.30

1.96

2.70

15.6

-10.4

37.7

Comorbidities

2.43

2.07

2.86

7.1

-20.8

30.5

Lifestyle and BMI

3.01

2.56

3.53

...

...

...

Maximal adjustment

2.61

2.22

3.07

...

...

...