Table 3 Hazard rations(95%CI) for new-onset depressive symptom according to changes in BMI

Female

 > -3%

28.11

1.384(0.999,1.917)

1.404(1.013,1.946)

1.389(0.997,1.935)

36.57

1.299(0.984,1.714)

1.318(0.998,1.741)

1.302(0.984,1.724)

25.25

0.867(0.594,1.265)

0.876(0.599,1.279)

0.877(0.599,1.285)

-3–3%

22.03

1.000

1.000

1.000

30.74

1.000

1.000

1.000

28.04

1.000

1.000

1.000

3–6%

25.84

1.233(0.880,1.728)

1.230(0.878,1.723)

1.258(0.895,1.768)

32.65

1.092(0.772,1.545)

1.079(0.762,1.528)

1.080(0.761,1.532)

30.81

1.143(0.794,1.646)

1.140(0.791,1.642)

1.146(0.794,1.654)

6–9%

27.08

1.315(0.867,1.994)

1.316(0.867,1.997)

1.343(0.881,2.047)

35.77

1.254(0.848,1.855)

1.245(0.841,1.843)

1.244(0.839,1.845)

28.57

1.027(0.641,1.644)

1.031(0.644,1.651)

1.028(0.640,1.651)

 > 9%

21.23

0.954(0.613,1.485)

0.962(0.618,1.498)

0.953(0.608,1.493)

32.88

1.103(0.749,1.626)

1.105(0.749,1.629)

1.109(0.750,1.641)

26.09

0.906(0.570,1.441)

0.914(0.575,1.455)

0.911(0.571,1.452)

Male

Unadjusted

Age-adjusted

^bM-adjusted

Unadjusted

Age-adjusted

^bM-adjusted

Unadjusted

Age-adjusted

^bM-adjusted

 > -3%

20.68

1.221(0.873,1.709)

1.220(0.872,1.706)

1.263(0.902,1.767)

22.74

1.035(0.775,1.381)

1.033(0.774,1.379)

1.041(0.777,1.394)

24.79

1.654(1.153,2.373) ^*

1.656(1.154,2.376) ^*

1.643(1.140,2.368) ^*

-3–3%

17.59

1.000

1.000

1.000

22.15

1.000

1.000

1.000

16.62

1.000

1.000

1.000

3–6%

16.46

0.923(0.651,1.308)

0.921(0.650,1.306)

0.933(0.656,1.326)

17.79

0.760(0.528,1.096)

0.760(0.527,1.096)

0.745(0.515,1.077)

19.32

1.202(0.831,1.737)

1.203(0.832,1.739)

1.231(0.848,1.787)

6–9%

13.87

0.754(0.450,1.266)

0.752(0.448,1.263)

0.748(0.444,1.260)

21.19

0.945(0.617,1.449)

0.947(0.618,1.451)

0.961(0.624,1.478)

21.19

1.349(0.829,2.196)

1.353(0.831,2.203)

1.327(0.811,2.172)

 > 9%

18.06

1.033(0.660,1.617)

1.033(0.660,1.617)

1.028(0.658,1.607)

26.24

1.251(0.827,1.890)

1.250(0.827,1.889)

1.176(0.775,1.785)

21.26

1.355(0.845,2.173)

1.353(0.844,2.170)

1.333(0.825,2.152)

Total

Unadjusted

Age-adjusted

^cM-adjusted

Unadjusted

Age-adjusted

^cM-adjusted

Unadjusted

Age-adjusted

cM-adjusted

 > -3%

24.31

1.329(1.053,1.676) ^*

1.331(1.055,1.680) ^*

1.305(1.031,1.651) ^*

29.22

1.181(0.969,1.439)

1.192(0.978,1.454)

1.171(0.957,1.433)

25.00

1.233(0.951,1.599)

1.236(0.953,1.603)

1.210(0.929,1.574)

-3–3%

19.46

1.000

1.000

1.000

25.91

1.000

1.000

1.000

21.28

1.000

1.000

1.000

3–6%

20.75

1.084(0.852,1.378)

1.077(0.846,1.370)

1.083(0.849,1.381)

24.28

0.917(0.715,1.175)

0.915(0.714,1.173)

0.908(0.706,1.168)

24.24

1.184(0.916,1.530)

1.180(0.913,1.526)

1.186(0.914,1.537)

6–9%

20.64

1.076(0.783,1.480)

1.069(0.777,1.469)

1.039(0.754,1.433)

28.13

1.119(0.842,1.488)

1.109(0.834,1.475)

1.092(0.818,1.458)

24.66

1.211(0.865,1.696)

1.209(0.863,1.693)

1.167(0.830,1.640)

 > 9%

19.60

1.009(0.737,1.381)

1.011(0.738,1.384)

0.968(0.705,1.329)

29.62

1.203(0.908,1.595)

1.204(0.908,1.596)

1.133(0.851,1.508)

23.55

1.140(0.819,1.585)

1.145(0.823,1.592)

1.083(0.775,1.512)

Interaction

Unadjusted

Age-adjusted

^bM-adjusted

Unadjusted

Age-adjusted

^bM-adjusted

Unadjusted

Age-adjusted

^bM-adjusted

Sex^*weight changes

1.033(0.995,1.073)

1.030(0.992,1.070)

1.006(0.964,1.049)

1.064(1.028,1.101)

1.060(1.024,1.097)

1.019(0.981,1.058)

1.067(1.025,1.111)

1.066(1.023,1.110)

1.029(0.983,1.077)