Table 3 Factors associations with willingness to get the COVID-19 vaccine among unvaccinated people (n = 1982) and sub-group analyses among preconception, pregnant, and breastfeeding individuals

A. Total (n = 1982)

Willing to be vaccinated

OR (95% CI)

aOR (95% CI)

Yes = 1447

No = 539

Variables

n (%)

n (%)

Spoken to HCP about vaccine during perinatal period

835 (57.7)

268 (49.7)

1.38 (1.13–1.68)

1.67 (1.32–2.12)

Beliefs: I have a good understanding of how the COVID-19 vaccine works

1077 (74.4)

328 (60.9)

1.87 (1.52–2.31)

0.89 (0.69–1.15)

Beliefs: COVID-19 vaccine is effective

1275 (88.1)

325 (60.3)

4.88 (3.86–6.17)

3.56 (2.70–4.69)

Worries: May lead to infertility

188 (13.0)

211 (39.2)

0.23 (0.18–0.29)

0.66 (0.49–0.88)

Worries: May lead to pregnancy loss or stillbirth

398 (27.5)

302 (56.0)

0.30 (0.24–0.37)

0.85 (0.65–1.13)

Worries: May lead to fetal growth and development problems

527 (36.4)

411 (76.3)

0.18 (0.14–0.22)

0.33 (0.24–0.46)

Worries: Child behavioural neurodevelopmental problems

409 (28.2)

336 (62.3)

0.24 (0.19–0.29)

0.64 (0.48–0.84)

Date of survey completion^a

0.98 (0.98–0.98)

0.99 (0.98–0.99)

B. Pre-conception (n = 254)

Willing to be vaccinated

OR (95% CI)

aOR (95% CI)

Yes = 171

No = 83

Variables

n (%)

n (%)

Spoken to HCP about vaccine during perinatal period

59 (34.5)

27 (32.5)

1.10 (0.63–1.91)

1.44 (0.75–2.74)

Beliefs: I have a good understanding of how the COVID-19 vaccine works

119 (69.6)

47 (56.6)

1.75 (1.02–3.02)

0.83 (0.43–1.58)

Beliefs: COVID-19 vaccine is effective

146 (85.4)

46 (55.4)

4.70 (2.56–8.61)

3.48 (1.76–6.88)

Worries: May lead to infertility

65 (38.0)

62 (74.7)

0.21 (0.12–0.37)

0.45 (0.22–0.93)

Worries: May lead to pregnancy loss or stillbirth

94 (55.0)

69 (83.1)

0.25 (0.13–0.47)

0.50 (0.21–1.20)

Worries: May lead to fetal growth and development problems

108 (63.2)

73 (88.0)

0.24 (0.11–0.49)

0.50 (0.18–1.38)

Worries: Child behavioural neurodevelopmental problems

85 (49.7)

58 (69.9)

0.43 (0.24–0.74)

1.07 (0.49–2.35)

Date of survey completion

0.98 (0.97–0.99)

0.99 (0.98–1.01)

C. Pregnancy (n = 1062)

Willing to be vaccinated

OR (95% CI)

aOR (95% CI)

Yes = 716

No = 346

Variables

n (%)

n (%)

Spoken to HCP about vaccine during perinatal period

592 (82.7)

210 (60.7)

3.09 (2.31–4.13)

3.34 (2.39–4.67)

Beliefs: I have a good understanding of how the COVID-19 vaccine works

533 (74.4)

220 (63.6)

1.67 (1.27–2.20)

0.84 (0.60–1.13)

Beliefs: COVID-19 vaccine is effective

636 (88.8)

226 (65.3)

4.22 (3.06–5.82)

2.79 (1.19–4.06)

Worries: May lead to infertility

62 (8.7)

100 (28.9)

0.233 (0.16–0.33)

0.55 (0.36–0.83)

Worries: May lead to pregnancy loss or stillbirth

254 (35.5)

197 (56.9)

0.42 (0.32–0.54)

1.07 (0.76–1.51)

Worries: May lead to fetal growth and development problems

326 (45.5)

278 (80.4)

0.20 (0.15–0.28)

0.33 (0.22–0.50)

Worries: Child behavioural neurodevelopmental problems

244 (34.1)

227 (65.6)

0.27 (0.21–0.36)

0.61 (0.43–0.86)

Date of survey completion

0.99 (0.98–0.99)

0.99 (0.98–1.00)

D. Breastfeeding (n = 670)

Willing to be vaccinated

OR (95% CI)

aOR (95% CI)

Yes = 560

No = 110

Variables

n (%)

n (%)

Spoken to HCP about vaccine during perinatal period

184 (32.9)

31 (28.2)

1.25 (0.79–1.96)

1.40 (0.82–2.40)

Beliefs: I have a good understanding of how the COVID-19 vaccine works

425 (75.9)

61 (55.5)

2.53 (1.66–3.86)

1.01 (0.58–1.75)

Beliefs: COVID-19 vaccine is effective

493 (88.0)

53 (48.2)

7.91 (5.03–12.45)

5.91 (3.43–10.19)

Worries: May lead to infertility

61 (10.9)

49 (44.6)

0.15 (0.10–0.24)

0.44 (0.23–0.83)

Worries: May lead to pregnancy loss or stillbirth

50 (8.9)

36 (32.7)

0.20 (0.12–0.33)

0.71 (0.34–1.47)

Worries: May lead to fetal growth and development problems

93 (16.6)

60 (54.6)

0.17 (0.11–0.26)

0.51 (0.25–1.04)

Worries: Child behavioural neurodevelopmental problems

80 (14.3)

51 (46.4)

0.19 (0.13–0.30)

0.60 (0.31–1.15)

Date of survey completion

0.98 (0.97–0.99)

0.98 (0.97–0.99)