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Table 1 Demographics and characteristics of child lead exposure cases resident in England reported to UKHSA in 2014–2020

From: ’As safe as houses; the risk of childhood lead exposure from housing in England and implications for public health’

Variable

Number

Percent

Total

n in model

SVA-Coefficient (95% CI)

P value

Sex

  

262

237

 

0.205

 Male

177

67

  

0.12 (-0.07, 0.30)

 

 Female

85

32

  

reference

 

 missing

4

1

    

Agea

  

266

241

0.001 (-0.12, 0.12)

0.986

Age Group

  

266

241

 

0.427

  < 1 year old

52

20

  

reference

 

 1–5

152

57

  

0.07 (-0.15, 0.29)

 

 6–10

47

18

  

0.22 (-0.06, 0.50)

 

 11–15

15

6

  

-0.09 (-0.50, 0.33)

 

BLC categories (µmols/L)

  

241

241

  

  < 0.48

22

8

    

 0.48–0.75

105

40

    

 0.76–1

45

17

    

 1.01–1.5

40

15

    

 1.51–2

12

5

    

 2.01–10

15

6

    

  > 10

2

 < 1

    

 missing

25

9

    

Year of report

  

266

241

 

 < 0.001

 2014

31

12

  

reference

 

 2015

33

12

  

0.49 (0.15, 0.83)

 

 2016

33

12

  

-0.20 (-0.54, 0.14)

 

 2017

50

19

  

-0.17 (-0.47, 0.13)

 

 2018

45

17

  

-0.22 (-0.53, 0.09)

 

 2019

39

15

  

-0.46 (-0.79, -0.14)

 

 2020

35

13

  

-0.25 (-0.59, 0.08)

 

Geographical location (UKHSA Centre)

  

265

240

 

0.449

 East Midlands

8

3

  

reference

 

 East of England

21

8

  

0.65 (0.03, 1.26)

 

 London

57

21

  

0.67 (0.10, 1.24)

 

 North East

4

2

  

0.98 (0.1, 1.83)

 

 North West

41

15

  

0.52 (-0.07, 1.11)

 

 South East

18

7

  

0.68 (0.05, 1.31)

 

 South West

15

6

  

0.61 (-0.05, 1.26)

 

 West Midlands

18

7

  

0.65 (0.03, 1.28)

 

 Yorkshire and Humber

83

31

  

0.85 (0.2, 1.41)

 

 missing

1

 < 1

    

Health Protection Teams (HPT)

  

266

-

-

-

 Bedfordshire and Hertfordshire

22

8

    

 Cheshire and Merseyside

28

11

    

 Cumbria and Lancashire

9

3

    

 East Midlands North

8

3

    

 Greater Manchester

4

2

    

 Hampshire and Isle of Wight

7

3

    

 North East

4

2

    

 North East and Central London

31

12

    

 North West London

16

6

    

 North Yorkshire and Humber

7

3

    

 South East London

10

4

    

 South West (South)

15

6

    

 South West London

1

 < 1

    

 Sussex and Surrey

10

4

    

 West Midlands East

16

6

    

 West Midlands West

2

 < 1

    

 West Yorkshire

76

29

    

Location/status

      

hospitalised

  

42

42

 

 < 0.001

 No

44

17

  

reference

 

 Yes

7

3

  

1.78 (1.17, 2.39)

 

 Not known

215

81

    

Deceased

1

 < 1

    

Status

  

241

241

 

0.042

 Open

22

8

  

reference

 

 Closed

233

88

  

-0.01 (-0.57, 0.54)

 

 Pending

11

4

  

0.29 (-0.04, 0.62)

 

IMD quintile

  

266

241

 

0.748

 1-most deprived

131

49

  

reference

 

 2

55

21

  

-0.06 (-0.30, 0.18)

 

 3

41

15

  

0.15 (-0.12–0.43)

 

 4

23

9

  

0.02 (-0.31, 0.35)

 

 5- least deprived

16

6

  

-0.24 (-0.62, 0.13)

 

Housing age (from VOA)

  

241

241

 

0.289

 Percentagea of housing built before 1973 in cases residential area

-

-

241

241

0.001 (-0.002, 0.004)

0.423

 Cases living in areas where 0% of housing built before 1973

16

6

    

 Cases living in areas where 0–20% of housing built before 1973

19

7

 

241

reference

 

 20–40%

7

3

  

0.03 (-0.57, 0.62)

 

 40–60%

29

11

  

0.04 (-0.37, 0.46)

 

 60–80%

84

32

  

0.01 (-0.33, 0.36)

 

 80–100%

127

48

  

0.15 (-0.19, 0.49)

 

Housing age of case (from OS data)

  

230

207

 

0.046

 Pre 1900

39

15

  

reference

 

 1900–1929

59

22

  

0.57 (0.29,0.86)

 

 1930–1949

54

20

  

0.03 (-0.27,0.33)

 

 1950–1966

45

17

  

0.22 (-0.10, 0.53)

 

 1967–1975

11

4

  

-0.06 (-0.53, 0.40)

 

 Post 1976

22

8

  

-0.11 (-0.49, 0.27)

 

 unknown

36

14

    

Housing age of case (from OS data- simplified categories) b

  

207

207

 

0.035

 Pre 1976

208

78

  

0.36 (0.03, 0.70)

 

 Post 1976

22

8

  

Reference

 

 missing

36

14

    

Housing type (from OS data)

  

245

220

 

0.620

 Self contained flat

31

12

  

reference

 

 Terraced

124

47

  

0.02 (-0.28, 0.31)

 

 Semi-detached

63

24

  

-0.11 (-0.43, 0.21)

 

 Detached

18

7

  

-0.05 (-0.47, 0.37)

 

 House of Multiple Occupation (HMO)

2

 < 1

  

-0.57 (-1.58, 0.43)

 

 Housing (other)

7

3

  

0.14 (-0.54, 0.82)

 

 missing

21

8

    

Source of report

  

261

241

 

 < 0.001

 Lab

205

77

  

reference

 

 HPT

56

21

  

-0.43 (-0.67, -0.19)

 

 Not known

5

2

    

Lab/sourceb

  

261

241

 

 < 0.001

 SAS Trace Element lab

192

72

  

reference

 

 Other

13

5

  

-0.29 (-0.67, 0.10)

 

 HPT

56

21

  

-0.43 (-0.67, -0.19)

 

 Not known

5

2

    

Lab name

  

261

241

 

0.048

 Alder Hey

5

2

  

reference

 

 Bristol

1

 < 1

  

-0.42 (-1.89, 1.06)

 

 Cardiff

4

2

  

0.15 (-0.77, 1.08)

 

 Guildford

48

18

  

0.14 (-0.52, 0.80)

 

 HPT

56

21

  

-0.18 (-0.86, 0.50)

 

 Imperial

26

10

  

0.34 (-0.35,1.03)

 

 Kings College

10

4

  

0.11 (-0.67,0.88)

 

 LEICSS (lab unnamed)

10

4

  

0.13 (-0.65, 0.90)

 

 Sandwell

21

8

  

0.20 (-0.51, 0.91)

 

 Sheffield

1

 < 1

  

-0.18 (-1.65, 1.30)

 

 The Doctors Lab

2

 < 1

  

-0.24 (-1.36, 0.87)

 

 Leeds

77

29

  

0.39 (-0.27, 1.05)

 

 Not known

5

2

    
  1. Description: (n = 266) (percentages subject to rounding). Single variable analysis (SVA) of association between Blood Lead Concentration (BLC) where possible (p < 0.05 shown in bold) using Health Protection Team (HPT) area as a random effect
  2. a Treated as a continuous variable in the model,
  3. b Variable used in the MVA models