| Men |  |  | Women |  |  |
---|---|---|---|---|---|---|
 | Unadjusted model | Fully-adjusted modela |  | Unadjusted model | Fully-adjusted modela | |
N (%) | OR (95% CI) | OR (95% CI) | N (%) | OR (95% CI) | OR (95% CI) | |
Do you have (or have you had) work and travel times requiring you not to sleep at night at least 50 days/year? | ||||||
Tobacco use | ||||||
 Relapse of tobacco use among ex-smokers at baseline | 15,452 |  |  | 15,464 |  |  |
  No | 12,483 (80.8) | 1.00 | 1.00 | 12,735 (82.4) | 1.00 | 1.00 |
  Yes | 2969 (19.2) | 1.20 (1.06–1.36) | 1.02 (0.90–1.15) | 2729 (17.6) | 1.17 (0.98–1.39) | 1.21 (0.99–1.42) |
 Changing status among ever-smokers at baseline | 25,402 |  |  | 25,592 |  |  |
  Smokers at baseline and remained current smokers at follow-up | 7145 (28.2) | 1.00 | 1.00 | 7146 (27.9) | 1.00 | 1.00 |
  Smokers at baseline and stopped at follow-up | 2805 (11.0) | 0.71 (0.61–0.82) | 0.93 (0.81–1.07) | 2982 (11.6) | 0.80 (0.66–0.96) | 0.85 (0.72–1.01) |
  Ex-smokers at baseline and remained ex-smokers at follow-up | 12,483 (49.1) | 0.85 (0.78–0.93) | 1.00 (0.91–1.09) | 12,735 (49.8) | 0.80 (0.71–0.90) | 0.86 (0.77–0.96) |
  Ex-smokers at baseline and relapsed at follow-up | 2969 (11.7) | 1.02 (0.90–1.17) | 1.03 (0.91–1.16) | 2729 (10.7) | 0.93 (0.78–1.12) | 1.03 (0.88–1.21) |
Cannabis use | ||||||
 Cannabis use among ever-users at baseline | 17,924 |  |  | 16,304 |  |  |
  No use in the past 12 months | 16,817 (93.8) | 1.00 | 1.00 | 15,514 (95.1) | 1.00 | 1.00 |
  Use in the past 12 months, < 1/month | 930 (5.2) | 0.82 (0.64–1.04) | 0.91 (0.73–1.14) | 628 (3.9) | 1.20 (0.87–1.64) | 1.12 (0.83–1.50) |
  Use in the past 12 months, ≥1/month | 177 (1.0) | 1.54 (1.02–2.34) | 1.54 (1.07–2.23) | 162 (1.0) | 0.59 (0.26–1.34) | 0.55 (0.26–1.19) |
Alcohol use (WHO risk levels) | 35,647 | Â | Â | 39,767 | Â | Â |
 Low risk | 27,554 (77.3) | 1.00 | 1.00 | 22,246 (55.9) | 1.00 | 1.00 |
 No use | 4977 (14.0) | 1.28 (1.16–1.41) | 1.13 (1.03–1.24) | 10,785 (27.1) | 1.17 (1.06–1.29) | 1.04 (0.95–1.14) |
 At risk | 3116 (8.7) | 1.09 (0.96–1.23) | 0.99 (0.87–1.12) | 6736 (17.0) | 0.93 (0.82–1.06) | 0.94 (0.84–1.06) |
Diet rich in sugar and fat | 35,647 | Â | Â | 39,767 | Â | Â |
 First quartile | 8842 (24.8) | 1.00 | 1.00 | 9861 (24.8) | 1.00 | 1.00 |
 Second quartile | 8981 (25.2) | 0.98 (0.89–1.08) | 0.95 (0.87–1.04) | 10,022 (25.2) | 0.95 (0.84–1.08) | 0.96 (0.86–1.08) |
 Third quartile | 8912 (25.0) | 0.91 (0.83–1.01) | 0.92 (0.84–1.01) | 9942 (25.0) | 0.99 (0.88–1.12) | 1.07 (0.95–1.19) |
 Fourth quartile | 8912 (25.0) | 0.79 (0.72–0.88) | 0.86 (0.78–0.95) | 9942 (25.0) | 0.99 (0.88–1.12) | 1.02 (0.91–1.14) |
Do you have (or have you had) work and travel times requiring you to go to bed after midnight at least 50 days/year? | ||||||
Tobacco use | ||||||
 Relapse of tobacco use among ex-smokers at baseline | 15,452 |  |  | 15,464 |  |  |
  No | 12,483 (80.8) | 1.00 | 1.00 | 12,735 (82.4) | 1.00 | 1.00 |
  Yes | 2969 (19.2) | 1.33 (1.20–1.48) | 1.08 (0.96–1.21) | 2729 (17.6) | 1.39 (1.21–1.60) | 1.25 (1.09–1.43) |
 Changing status among ever-smokers at baseline | 25,402 |  |  | 25,592 |  |  |
  Smokers at baseline and remained current smokers at follow-up | 7145 (28.2) | 1.00 | 1.00 | 7146 (27.9) | 1.00 | 1.00 |
  Smokers at baseline and stopped at follow-up | 2805 (11.0) | 0.83 (0.74–0.94) | 0.92 (0.83–1.02) | 2982 (11.6) | 0.79 (0.69–0.91) | 0.81 (0.72–0.91) |
  Ex-smokers at baseline and remained ex-smokers at follow-up | 12,483 (49.1) | 0.77 (0.71–0.83) | 0.90 (0.84–0.97) | 12,735 (49.8) | 0.64 (0.58–0.71) | 0.78 (0.72–0.84) |
  Ex-smokers at baseline and relapsed at follow-up | 2969 (11.7) | 1.02 (0.91–1.14) | 1.01 (0.92–1.11) | 2729 (10.7) | 0.89 (0.77–1.03) | 0.98 (0.87–1.10) |
Cannabis use | ||||||
 Cannabis use among ever-users at baseline | 17,924 |  |  | 16,304 |  |  |
 No use in the past 12 months | 16,817 (93.8) | 1.00 | 1.00 | 15,514 (95.1) | 1.00 | 1.00 |
 Use in the past 12 months, < 1/month | 930 (5.2) | 0.87 (0.72–1.05) | 1.06 (0.90–1.25) | 628 (3.9) | 1.67 (1.34–2.10) | 1.32 (1.08–1.61) |
 Use in the past 12 months, ≥1/month | 177 (1.0) | 1.46 (1.03–2.08) | 1.40 (1.02–1.91) | 162 (1.0) | 1.29 (0.81–2.07) | 0.88 (0.58–1.34) |
Alcohol use (WHO risk levels) | 35,647 | Â | Â | 39,767 | Â | Â |
 Low risk | 27,554 (77.3) | 1.00 | 1.00 | 22,246 (55.9) | 1.00 | 1.00 |
 No use | 4977 (14.0) | 1.11 (1.02–1.20) | 1.04 (0.96–1.12) | 10,785 (27.1) | 1.06 (0.97–1.15) | 0.97 (0.90–1.04) |
 At risk | 3116 (8.7) | 1.22 (1.11–1.35) | 1.12 (1.02–1.24) | 6736 (17.0) | 1.25 (1.13–1.37) | 1.14 (1.05–1.24) |
Diet rich in sugar and fat | 35,647 | Â | Â | 39,767 | Â | Â |
 First quartile | 8842 (24.8) | 1.00 | 1.00 | 9861 (24.8) | 1.00 | 1.00 |
 Second quartile | 8981 (25.2) | 0.95 (0.88–1.03) | 0.94 (0.87–1.01) | 10,022 (25.2) | 0.94 (0.85–1.04) | 0.95 (0.88–1.03) |
 Third quartile | 8912 (25.0) | 0.98 (0.90–1.06) | 0.96 (0.89–1.03) | 9942 (25.0) | 0.94 (0.85–1.04) | 0.94 (0.87–1.02) |
 Fourth quartile | 8912 (25.0) | 0.88 (0.81–0.96) | 0.91 (0.95–0.98) | 9942 (25.0) | 0.99 (0.90–1.09) | 0.91 (0.83–0.99) |