Fig. 2

Misclassification errors for varying values of true sensitivity and specificity under various prevalence thresholds. The prevalence thresholds considered were (A) low, (B) medium, (C) high. The assumed sensitivity and specificity for adjustment was 90%. The dotted lines indicate pre-determined values of \(\alpha\) and \(\beta\). The black dot represents alignment between the true and assumed sensitivity and specificity values, which should always be contained in the lower left square