Table 1 Study sample characteristics according to cannabidiol use (n = 1969)

Age (mean) in years (0)

51.7 (18.5)

52.8 (18.4)

42.2 (16.7)

 < 10^–3

/

Age (in years) (0)

 18–24

205 (10.4)

170 (9.6)

35 (17.8)

 < 10^–3

17.1 [12.5 – 22.9]^a

 25–34

278 (14.1)

228 (12.9)

50 (25.4)

18.0 [13.9 – 23.0]^a

 35–49

440 (22.4)

384 (21.7)

56 (28.4)

12.7 [9.9 – 16.2]^a

 50–64

503 (25.6)

469 (26.5)

34 (17.3)

6.7 [4.9 – 9.3]^b

 65–74

291 (14.8)

276 (15.6)

15 (7.6)

5.2 [3.1 – 8.4]^bc

 ≥ 75

252 (12.8)

245 (13.8)

7 (3.6)

2.8 [1.3 – 5.7]^bc

Gender (0)

 Men

909 (46.2)

803 (45.3)

106 (53.8)

0.023

11.7 [9.7 – 13.9]

 Women

1060 (53.8)

969 (54.7)

91 (46.2)

8.6 [7.0 – 10.4]

Country of birth (0)

 France

1858 (94.4)

1670 (94.2)

188 (95.4)

0.493

10.1 [8.8 – 11.6]^a

 Outside France

111 (5.6)

102 (5.8)

9 (4.6)

8.1 [4.2 – 15.0]^a

Region (0)

 Alsace-Champagne-Ardenne-Lorraine

174 (8.8)

148 (8.4)

26 (13.2)

0.327

14.9 [10.4 – 21.1]^a

 Aquitaine-Limousin-Poitou–Charentes

197 (10.0)

180 (10.2)

17 (8.6)

8.6 [5.4 – 13.5]^a

 Auvergne-Rhône-Alpes

236 (12.0)

206 (11.6)

30 (15.2)

12.7 [9.0 – 17.6]^a

 Burgundy-Franche-Comté

85 (4.3)

75 (4.2)

10 (5.1)

11.8 [6.4 – 20.7]^a

 Brittany

115 (5.8)

103 (5.8)

12 (6.1)

10.4 [6.0 – 17.6]^a

 Centre-Val de Loire

89 (4.5)

83 (4.7)

6 (3.0)

6.7 [3.0 – 14.3]^a

 Île-de-France

333 (16.9)

301 (17.0)

32 (16.2)

9.6 [6.9 – 13.3]^a

 Languedoc-Roussillon-Midi-Pyrénées

183 (9.3)

166 (9.4)

17 (8.6)

9.3 [5.8 – 14.5]^a

 Nord-Pas-de-Calais-Picardy

167 (8.5)

154 (8.7)

13 (6.6)

7.8 [4.6 – 13.0]^a

 Normandy

108 (5.5)

102 (5.8)

6 (3.0)

5.6 [2.5 – 11.9]^a

 Pays de la Loire

121 (6.1)

107 (6)

14 (7.1)

11.6 [6.9 – 18.7]^a

 Provence- Alpes-Côte d'Azur

161 (8.2)

147 (8.3)

14 (7.1)

8.7 [5.2 – 14.2]^a

City size (0)

 < 2 000 inhabitants (rural area)

537 (27.3)

488 (27.5)

49 (24.9)

0.839

9.1 [7.0 – 11.9]^a

 2 000—20 000 inhabitants

738 (37.5)

663 (37.4)

75 (38.1)

10.2 [8.2 – 12.6]^a

 20 000—100 000 inhabitants

414 (21.0)

372 (21.0)

42 (21.3)

10.1 [7.6 – 13.5]^a

 > 100 000 inhabitants

280 (14.2)

249 (14.1)

31 (15.7)

11.1 [7.9 – 15.3]^a

Socio-professional status (0)

 Farmer/ craftsperson, trader or business manager/ skilled or unskilled worker

315 (16.0)

270 (15.2)

45 (22.8)

 < 10^–3

14.3 [10.8 – 18.6]^a

 Executive or higher intellectual profession/ Intermediate profession

503 (25.5)

438 (24.7)

65 (33.0)

12.9 [10.3 – 16.2]^a

 Employee

324 (16.5)

285 (16.1)

39 (19.8)

12.0 [8.9 – 16.1]^a

 Pensioner

666 (33.8)

636 (35.9)

30 (15.2)

4.5 [3.2 – 6.4]

 Other, no professional activity

161 (8.2)

143 (8.1)

18 (9.1)

11.2 [7.13 – 17.1]^a

Educational level (0)

 No upper secondary school certificate

668 (33.9)

608 (34.3)

60 (30.5)

0.278

9.0 [7.0 – 11.4]^a

 At least upper secondary school certificate

1301 (66.1)

1164 (65.7)

137 (69.5)

10.5 [9.0 – 12.3]^a

Dependent children (0)

 No

1361 (69.1)

1240 (70.0)

121 (61.4)

0.014

8.9 [7.5 – 10.5]

 Yes

608 (30.9)

532 (30.0)

76 (38.6)

12.5 [10.1 – 15.4]

Difficulty paying bills (0)³

 Easy

1238 (62.9)

1115 (62.9)

123 (62.4)

0.893

9.9 [8.4 – 11.7]^a

 Difficult

731 (37.1)

657 (37.1)

74 (37.6)

10.1 [8.1 – 12.5]^a

Tobacco use (0.4)

 No

1493 (76.1)

1410 (79.8)

83 (42.6)

 < 10^–3

5.6 [4.5 – 6.8]

 Yes

468 (23.9)

356 (20.2)

112 (57.4)

23.9 [20.3 – 28.0]

Alcohol use (0.3)⁴

 Never

516 (26.3)

471 (26.7)

45 (23.0)

0.074

8.7 [6.6 – 11.5]^a

 Occasional

965 (49.2)

875 (49.5)

90 (45.9)

9.3 [7.6 – 11.3]^a

 Regular

482 (24.6)

421 (23.8)

61 (31.1)

12.7 [10.0 – 15.9]^a

Cannabis use (0.5)

 No

1840 (93.9)

1715 (96.9)

125 (65.8)

 < 10^–3

6.8 [5.7 – 8.0]

 Yes

119 (6.1)

54 (3.1)

65 (34.2)

54.6 [45.5 – 63.4]

Self-reported general health status (0)⁵

 Good

1232 (62.6)

1112 (62.8)

120 (60.9)

0.023

9.7 [8.2 – 11.5]^a

 Quite good

559 (28.4)

510 (28.8)

49 (24.9)

8.8 [6.7 – 11.4]^a

 Poor

178 (9.0)

150 (8.5)

28 (14.2)

15.7 [11.1 – 21.9]

Chronic disease or health problem (0)

 No

995 (50.5)

912 (51.5)

83 (42.1)

0.020

8.3 [6.8 – 10.2]^a

 One

712 (36.2)

634 (35.8)

78 (39.6)

11.0 [8.9 – 13.5]^ab

 More than one

262 (13.3)

226 (12.8)

36 (18.3)

13.7 [10.1 – 18.5]^b

‘Alternative medicines provide better solutions to health problems than conventional medicines’ (0.3)

 Disagree

497 (25.3)

456 (25.8)

41 (20.9)

 < 10^–3

8.3 [6.1 – 11.0]^a

 Agree

597 (30.4)

500 (28.3)

97 (49.5)

16.3 [13.5 – 19.4]

 No opinion

869 (44.3)

811 (45.9)

58 (29.6)

6.7 [5.2 – 8.5]^a

Preferred means to obtain information (0)

 Television

621 (31.5)

556 (31.4)

65 (33)

0.864

10.5 [8.3 – 13.1]^a

 Radio

211 (10.7)

188 (10.6)

23 (11.7)

10.9 [7.3 – 15.9]^a

 Print media

190 (9.7)

173 (9.8)

17 (8.6)

9.0 [5.6 – 14.0]^a

 Online media

205 (10.4)

185 (10.4)

20 (10.2)

9.8 [6.4 – 14.7]^a

 Other internet ⁶

345 (17.5)

307 (17.3)

38 (19.3)

11.0 [8.1 – 14.8]^a

 Close family members and friends

397 (20.2)

363 (20.5)

34 (17.3)

8.6 [6.2 – 11.8]^a

Had heard of CBD (0)⁷

 Had never heard of CBD

605 (30.7)

605 (34.1)

0 (0)

 < 10^–3

/

 Only heard of the term ‘CBD’

477 (24.2)

434 (24.5)

43 (21.8)

9.0 [6.8 – 11.9]^a

 Knew a little about CBD

591 (30.0)

539 (30.4)

52 (26.4)

8.8 [6.8 – 11.4]^a

 Had good knowledge of CBD

194 (9.9)

139 (7.8)

55 (27.9)

28.4 [22.4 – 35.1]

 Had very good knowledge of CBD

102 (5.2)

55 (3.1)

47 (23.9)

46.1 [36.6 – 55.9]

‘Do you think that CBD is harmful for health?’ (30.7)⁷

 Did not want to answer

6 (0.4)

5 (0.4)

1 (0.5)

 < 10^–3

16.7 [1.2 – 77.0]^ab

 No opinion

325 (23.8)

308 (26.4)

17 (8.6)

5.2 [3.3 – 8.3]^a

 Not at all

397 (29.1)

286 (24.5)

111 (56.3)

28.0 [23.8 – 32.6]^b

 Slightly harmful

382 (28.0)

342 (29.3)

40 (20.3)

10.5 [7.8 – 13.9]^a

 Quite harmful

171 (12.5)

155 (13.3)

16 (8.1)

9.4 [5.8 – 14.8]^a

 Very harmful

83 (6.1)

71 (6.1)

12 (6.1)

14.5 [8.3 – 23.9]^ab