Fig. 1
From: The secular trend of enterovirus A71 after the implementation of preventive measures in Taiwan
The incidence of enterovirus infection with severe complications and mortality in children under six-year-old, 1998–2020. The incidence of enterovirus infection with severe complications (EVSC) and mortality rate decreased significantly from 1998 to 2020. The average annual percentage change (AAPC) for the incidence of EVSC was −9.19% (95%CI −3.40, −14.64, P = 0.0022). The AAPC for mortality in children younger than six years of age was −12.81% (95%CI −7.73, −17.63, P < 0.0001)