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Table 3 Service engagement and outcomes, and sexual risk and prevention behaviours associated with self-reported current PrEP use in self-perceived HIV-negative/unknown MSM with identified PrEP-need, June to August 2019

From: PrEP use and unmet PrEP-need among men who have sex with men in London prior to the implementation of a national PrEP programme, a cross-sectional study from June to August 2019

 

MSM with identified PrEP-needa,b

OR (95% CI)

p valuec

aORd (95% CI)

p valuec

Current PrEP use

No current PrEP use

n = 201

n = 431

Service engagement and outcomes

 ≥ 4 HIV tests in the last year

 No

41.5% (83/200)

86.9% (351/404)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

58.5% (117/200)

13.1% (53/404)

9.34 (6.24–14.0)

 

9.68 (6.35–14.8)

 

Location of last HIV test

 Other

8.0% (16/200)

30.3% (125/413)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 SHC

92.0% (184/200)

69.7% (288/413)

4.99 (2.87–8.67)

 

5.28 (2.97–9.36)

 

STI diagnosis in the last year

 No

35.8% (72/201)

80.8% (344/426)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

64.2% (129/201)

19.3% (82/426)

7.52 (5.16–10.9)

 

8.46 (5.69–12.6)

 

Sexual risk and prevention behaviours

 ≥ 5 CAS partners in the last year

 No

33.3% (66/198)

81.8% (342/418)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

66.7% (132/198)

18.2% (76/418)

9.00 (6.11–13.2)

 

10.1 (6.71–15.2)

 

 ≥ 2 casual CAS partners in the last year

 No

24.6% (46/187)

73.0% (267/366)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

75.4% (141/187)

27.1% (99/366)

8.27 (5.51–12.4)

 

9.21 (6.03–14.1)

 

Chemsex in the last yeare

 No

62.9% (122/194)

82.1% (339/413)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

37.1% (72/194)

17.9% (74/413)

2.70 (1.84–4.00)

 

2.85 (1.90–4.27)

 

Purchase of antibiotics to prevent STIsf

 No

86.3% (170/197)

96.4% (397/412)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

13.7% (27/197)

3.6% (15/412)

4.20 (2.18–8.10)

 

4.58 (2.33–9.02)

 

Ever used PEP

 No

55.8% (111/199)

86.5% (370/428)

1.00 (ref)

 < 0.001

1.00 (ref)

 < 0.001

 Yes

44.2% (88/199)

13.6% (58/428)

5.06 (3.41–7.50)

 

4.95 (3.30–7.41)

 
  1. aBased on 632 self-perceived HIV negative/unknown MSM who provided information on current PrEP use and had identified PrEP-need defined as self-reported CAS in the last three months and/or CAS with a HIV-positive/unknown status partner not known to be on ART in the last year; 31.8% (201/632) of men reported current PrEP use
  2. bAnalyses exclude 41 current PrEP users that did not have identified PrEP-need
  3. cLikelihood ratio test (LRT) p value
  4. dAdjusted for age-group and education since age 16
  5. eChemsex defined as self-reported use of ketamine, gamma hydroxybutyrate (GHB)/gamma butyrolactone (GBL), mephedrone and/or meth amphetamine before or during sex
  6. fPrivate or internet purchase. OR odds ratio, aOR adjusted odds ratio, PrEP = HIV pre-exposure prophylaxis, PEP = HIV post-exposure prophylaxis, SHC sexual health clinic, STI sexually transmitted infection, CAS condomless anal sex, SHC sexual health clinic