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Table 3 Interactive effect analysis of trouble sleeping and depression severity

From: Interaction between trouble sleeping and depression on hypertension in the NHANES 2005–2018

Trouble sleeping Depression Moderate depression Moderately severe depression Severe depression
OR 95% CI P OR 95% CI P OR 95% CI P
0 0 Ref    Ref    Ref   
0 1 0.868 0.694–1.087 0.216 0.987 0.655–1.488 0.951 1.219 0.552–2.695 0.621
1 0 1.286 1.157–1.430  < 0.001 1.287 1.157–1.433  < 0.001 1.290 1.160–1.435  < 0.001
1 1 1.769 1.444–2.167  < 0.001 1.749 1.237–2.473  < 0.001 1.576 1.046–2.372  < 0.001
RERI (95%CI) 0.614 (0.214–1.014) 0.474 (-0.216 – 1.164) 0.066 (-1.016—1.148)
AP (95%CI) 0.347 (0.172–0.523) 0.271 (-0.056 – 0.598) 0.042 (-0.638—0.722)
S (95%CI) 4.969 (1.022–24.155) 2.725 (0.520 – 14.291) 1.129 (0.143 – 8.914)
  1. Reference (Ref.). Ref reference, RERI relative excess risk due to interaction, AP attributable proportion of interaction, S synergy index, OR odd ratio, CI confidence interval