Table 5 Incidence rates and hazard ratios of stroke for leisure time physical activity

Male

0–1.6

 > 1.6–3.6

 > 3.6–16.3

Female

0–1.5

 > 1.5–3.1

 > 3.1–16.3

Total

 Stroke, ischemic and hemorrhagic

  Number of events

490

461

307

  Person-years (py)

148,334

145,194

147,037

  Event rate per 100,000 py^a

330.3

317.5

208.8

  HR (95% CI)^a

0.96 (0.94–0.99)

1.00 (reference)

0.88 (0.77–1.00)

0.79 (0.69–0.91)

  HR (95% CI)^b

0.97 (0.94–0.99)

1.00 (reference)

0.92 (0.80–1.05)

0.83 (0.71–0.97)

  HR (95% CI)^c

0.97 (0.94–1.00)

1.00 (reference)

0.93 (0.81–1.07)

0.86 (0.73–1.00)

 Stroke, ischemic

  Number of events

332

313

213

  Person-years

148,334

145,194

147,037

  Event rate per 100,000 py^a

223.8

215.6

144.9

  HR (95% CI)^a

0.97 (0.94–1.01)

1.00 (reference)

0.87 (0.75–1.02)

0.81 (0.69–0.97)

  HR (95% CI)^b

0.99 (0.95–1.02)

1.00 (reference)

0.93 (0.79–1.10)

0.87 (0.72–1.04)

  HR (95% CI)^c

0.99 (0.96–1.02)

1.00 (reference)

0.93 (0.78–1.10)

0.90 (0.74–1.09)

 Stroke, hemorrhagic

  Number of events

96

75

58

  Person-years

148,334

145,194

147,037

  Event rate per 100,000 py^a

64.7

51.7

39.4

  HR (95% CI)^a

0.93 (0.87–0.99)

1.00 (reference)

0.74 (0.55–1.01)

0.75 (0.54–1.04)

  HR (95% CI)^b

0.93 (0.86–0.99)

1.00 (reference)

0.76 (0.55–1.04)

0.74 (0.53–1.05)

  HR (95% CI)^c

0.93 (0.86–0.99)

1.00 (reference)

0.76 (0.55–1.06)

0.75 (0.52–1.08)

Male

 Stroke, ischemic and hemorrhagic

  Number of events

203

221

127

  Person-years

48,129

46,193

47,516

  Event rate per 100,000 py^a

421.8

478.4

267.3

  HR (95% CI)^a

0.97 (0.93–1.00)

1.00 (reference)

0.96 (0.79–1.16)

0.75 (0.60–0.94)

  HR (95% CI)^b

0.97 (0.94–1.01)

1.00 (reference)

0.95 (0.77–1.16)

0.78 (0.61–0.98)

  HR (95% CI)^c

0.97 (0.93–1.01)

1.00 (reference)

0.94 (0.76–1.16)

0.78 (0.61–0.99)

 Stroke, ischemic

  Number of events

147

146

95

  Person-years

48,129

46,193

47,516

  Event rate per 100,000 py^a

305.4

316.1

199.9

  HR (95% CI)^a

0.98 (0.94–1.03)

1.00 (reference)

0.87 (0.69–1.09)

0.77 (0.60–1.00)

  HR (95% CI)^b

0.99 (0.95–1.03)

1.00 (reference)

0.84 (0.66–1.08)

0.77 (0.58–1.01)

  HR (95% CI)^c

0.98 (0.94–1.03)

1.00 (reference)

0.82 (0.64–1.06)

0.75 (0.56–1.00)

 Stroke, hemorrhagic

  Number of events

35

41

20

  Person-years

48,129

46,193

47,516

  Event rate per 100,000 py^a

72.7

88.8

42.1

  HR (95% CI)^a

0.93 (0.85–1.02)

1.00 (reference)

1.08 (0.69–1.70)

0.70 (0.40–1.21)

  HR (95% CI)^b

0.96 (0.87–1.05)

1.00 (reference)

1.14 (0.70–1.86)

0.83 (0.47–1.48)

  HR (95% CI)^c

0.96 (0.87–1.06)

1.00 (reference)

1.16 (0.69–1.93)

0.87 (0.48–1.58)

Female

 Stroke, ischemic and hemorrhagic

  Number of events

287

240

180

  Person-years

100,205

99,001

99,522

  Event rate per 100,000 py^a

286.4

242.4

180.9

  HR (95% CI)^a

0.95 (0.92–0.99)

1.00 (reference)

0.82 (0.69–0.97)

0.82 (0.68–0.99)

  HR (95% CI)^b

0.96 (0.92–1.00)

1.00 (reference)

0.89 (0.74–1.07)

0.88 (0.72–1.07)

  HR (95% CI)^c

0.97 (0.93–1.02)

1.00 (reference)

0.92 (0.76–1.11)

0.91 (0.74–1.13)

Stroke, ischemic

 Number of events

185

167

118

  Person-years

100,205

99,0001

99,522

  Event rate per 100,000 py^a

184.6

168.7

118.6

  HR (95% CI)^a

0.96 (0.92–1.01)

1.00 (reference)

0.88 (0.72–1.09)

0.85 (0.67–1.07)

  HR (95% CI)^b

0.98 (0.93–1.03)

1.00 (reference)

1.00 (0.80–1.25)

0.95 (0.74–1.23)

  HR (95% CI)^c

0.99 (0.94–1.05)

1.00 (reference)

1.02 (0.80–1.28)

1.03 (0.79–1.33)

 Stroke, hemorrhagic

  Number of events

61

34

38

  Person-years

100,205

99,001

99,521

  Event rate per 100,000 py^a

60.9

34.4

38.2

  HR (95% CI)^a

0.92 (0.84–1.02)

1.00 (reference)

0.55 (0.36–0.83)

0.78 (0.52–1.18)

  HR (95% CI)^b

0.89 (0.80–0.99)

1.00 (reference)

0.53 (0.35–0.84)

0.69 (0.45–1.08)

  HR (95% CI)^c

0.89 (0.80–0.99)

1.00 (reference)

0.56 (0.36–0.88)

0.70 (0.44–1.09)