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Table 2 Mediated and unmediated effects via patient activation measure (PAM) for the “Live your life without diabetes” intervention on weight, waist circumference and systolic blood pressure at 12 months follow-up in adults at high risk of type 2 diabetes (n = 127)a

From: Is patient activation a mediator of the effect of a health promoting intervention in adults at high risk of type 2 diabetes? A longitudinal path model analysis within a randomised trial

Outcome (OC)

 

Weight (kg)

Waist circumference (cm)

Systolic blood pressure (mmHg)

estimate (95% CI)b

estimate (95% CI)b

estimate (95% CI)b

Path coefficients

a paths

  a1

Intervention- > PAM3

3.36 (−1.62 to 8.34)

3.78 (−1.21 to 8.76)

3.42 (− 1.55 to 8.38)

  a2

Intervention- > PAM12

0.13 (−6.21 to 6.47)

2.08 (−3.20 to 7.36)

0.27 (−5.94 to 6.48)

  overall a

Intervention- > − > PAM12

3.96 (−2.30 to 10.22)

4.26 (− 1.52 to 10.04)

4.05 (− 2.08 to 10.17)

b paths (constrained)

PAM (per 10 score points) - > OC

−0.13 (−0.36 to 0.10)

−0.05 (−0.41 to 0.30)

−0.43 (− 1.05 to 0.19)

Effects

 Mediated

Intervention- > PAM- > OC12

(all paths including ≥1 PAM measure)

−0.09 (− 0.38 to 0.20)

−0.04 (− 0.36 to 0.28)

−0.31 (− 1.10 to 0.49)

 Unmediated

Intervention- > OC12 (all paths not via PAM)

−1.00 (− 3.05 to 1.05)

− 1.82 (−4.12 to 0.49)

−2.42 (− 6.18 to 1.34)

Total (c)

 

−1.09 (− 3.05 to 0.87)

−1.86 (− 4.10 to 0.39)

−2.73 (− 6.34 to 0.87)

Successful bootstrap out of 50

 

45

50

46

  1. At baseline residual covariance between all mediators and outcome. At each follow-up time residual covariance between all mediators. For each mediator and the outcome residual covariance over time
  2. a According to Fig. 1. bAdjusted for sex, age, educational level