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Table 2 Mediation and sensitivity analyses of the mediation effect of household income as the mediator and childhood undervaccination as the outcome

From: Association between a single mother family and childhood undervaccination, and mediating effect of household income: a nationwide, prospective birth cohort from the Japan Environment and Children’s Study (JECS)

 

Crude model

Adjusted model

ACME (95% CI)a

0.0242 (0.0217 to 0.03)

0.0082 (0.0068 to 0.01)

ADE (95% CI)a

0.0929 (0.0766 to 0.11)

0.0700 (0.0542 to 0.09)

Total effect (95% CI)a

0.1171 (0.1006 to 0.13)

0.0783 (0.0623 to 0.09)

Proportion mediated (95% CI)a

0.207 (0.200 to 0.21)

0.105 (0.099 to 0.11)

Rho at which ACME = 0b

−0.07 to −0.06

−0.06

  1. Estimates are risk differences, except for the proportion mediated
  2. “Rho at which ACME = 0” refers to the sensitivity parameter, rho at which the CI of ACME includes zero. The model was adjusted for maternal age and educational level
  3. CI confidence interval, ACME average causal mediation effect, ADE average direct effect
  4. aCalculated with the dataset with missing data imputed (n = 82,462)
  5. bCalculated with the complete case dataset (n = 72,612)