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Table 5 The risk factors of cognitive impairment were analyzed by regression logistics analysis

From: The cognitive impairment and risk factors of the older people living in high fluorosis areas: DKK1 need attention

Variables in the Equation

 

B

S.E.

Wald

df

Sig.

Exp(B)

95.0% C.I.for EXP(B)

Lower

Upper

Step 1a

 Group

0.646

0.677

0.91

1

0.34

1.908

0.506

7.188

 Gender

0.381

0.376

1.026

1

0.311

1.464

0.7

3.06

 Age

  

14.678

2

0.001

   

  Age (1)

0.765

0.264

8.42

1

0.004

2.15

1.282

3.606

     Age (2)

1.41

0.417

11.432

1

0.001

4.094

1.808

9.268

 Education

  

16.02

3

0.001

   

  Education (1)

1.035

0.325

10.145

1

0.001

2.815

1.489

5.322

  Education (2)

1.405

0.431

10.618

1

0.001

4.076

1.751

9.49

  Education (3)

2.015

0.884

5.202

1

0.023

7.502

1.328

42.389

 Height

−0.004

0.022

0.037

1

0.848

0.996

0.954

1.039

 Weight

−0.008

0.016

0.254

1

0.614

0.992

0.962

1.023

 Fluoride

20.047

6.604

9.215

1

0.002

5.08E+ 08

1.22E+ 03

2.12E+ 14

 DKK1

0.318

0.081

15.323

1

0.000

1.374

1.172

1.611

 Cigarette smoking

0.132

0.391

0.113

1

0.736

1.141

0.53

2.455

 Alcohol consumption

−20.128

4.02E+ 04

0.000

1

1

0.000

0.000

 

 Dental fluorosis

  

7.896

2

0.019

   

  Fluorosis (1)

1.734

0.687

6.365

1

0.012

5.665

1.472

21.792

  Fluorosis (2)

1.683

0.787

4.58

1

0.032

5.384

1.152

25.153

 Hypertension

−0.04

0.266

0.022

1

0.881

0.961

0.57

1.619

 Hyperglycemia

0.118

0.476

0.062

1

0.804

1.125

0.443

2.858

 Hyperlipemia

−0.379

0.425

0.795

1

0.373

0.684

0.297

1.575

 SOD

−0.009

0.008

1.422

1

0.233

0.991

0.975

1.006

 GSH

0.004

0.009

0.157

1

0.692

1.004

0.985

1.022

 MDA

0.014

0.025

0.343

1

0.558

1.014

0.967

1.065

 APOE

  

0.491

4

0.974

   

  APOE(1)

20.42

2.67E+ 04

0

1

0.999

7.38E+ 08

0

 

  APOE(2)

20.36

2.67E+ 04

0

1

0.999

6.96E+ 08

0

 

  APOE(3)

20.499

2.67E+ 04

0

1

0.999

7.99E+ 08

0

 

  APOE(4)

21.105

2.67E+ 04

0

1

0.999

1.47E+ 09

0

 

 Constant

8.132

4.06E+ 04

0

1

1

3.40E+ 03

  
  1. Notes
  2. 1. The age variables in this study are calculated in comparison with the “60–69 years old” group. The parameter of the Age (1) row gives the OR value and P value to the “70–79 years old” group relative to “60–69 years old” group. The parameter of the Age (2) row gives the OR value and P value to the “80 years old and above” group relative to “60–69 years old” group
  3. 2. The variables of education level in this study are calculated in comparison with the “illiterate” group. The parameter of the Education (1) row gives the OR value and P value of the “primary school” group relative to “illiterate” group. The parameter of the Education (2) row gives the OR value and P value to the “junior high school” group relative to “illiterate” group. The parameter of the Education (3) row gives the OR value and P value to the “high school and above” group relative to “illiterate” group
  4. 3. The variables of dental fluorosis in this study are calculated in comparison with the “normal teeth” group. The parameter of the Fluorosis (1) row gives the OR value and P value of the “dental fluorosis” group relative to “normal teeth” group. The parameter of the Fluorosis (2) row gives the OR value and P value to the “all dentures (no teeth or false braces)” group relative to “normal teeth” group
  5. 4. The APOE variables in this study are calculated in comparison with “E2/E2” group. The parameter in APOE (1) row gives the OR value and P value to “E2/E3” group relative to “E2/E2” group”. The parameter in APOE (2) row gives the OR value and P value to the “E2/E4” group relative to “E2/E2” group. The parameter in APOE (3) row gives the OR value and P value to the “E3/E3” group relative to “E2/E2” group. The parameter in APOE (4) row gives the OR value and P value to the “E3/E4” group relative to “E2/E2” group
  6. APOE apolipoprotein E, DKK1 dickkopf-1, GSH glutathione, MDA malondialdehyde, SOD superoxide dismutase