Table 3 Factors associated with treatment interruption

 Female

1 [ref]

0

1 [ref]

0

 Male

1.04 [1.03 - 1.06]

<0.000001

0.91 [0.89 - 0.93]

<0.000001

 0-14

1 [ref]

<0.000001

1 [ref]

0

 15-24

1.04 [1.01 - 1.07]

0.014073

1.08 [0.97 - 1.19]

0.16165

 25-34

0.84 [0.81 - 0.86]

<0.000001

1.19 [1.08 - 1.32]

0.000539

 35-44

0.61 [0.6 - 0.63]

<0.000001

1.13 [1.02 - 1.25]

0.0185935

 45-59

0.53 [0.51 - 0.54]

<0.000001

1.08 [0.97 - 1.19]

0.147981

 60+

0.51 [0.49 - 0.54]

<0.000001

1.22 [1.08 - 1.36]

0.000822

 South-South

1 [ref]

0

1 [ref]

0

 North Central

0.4 [0.38 - 0.41]

<0.000001

0.4 [0.38 - 0.42]

<0.000001

 North East

1.41 [1.39 - 1.43]

<0.000001

1.36 [1.32 - 1.4]

<0.000001

 North West

1.33 [1.31 - 1.36]

<0.000001

0.83 [0.8 - 0.85]

<0.000001

 South West

2.34 [2.3 - 2.38]

<0.000001

1.99 [1.92 – 2.06]

0

 Primary level

1 [ref]

0

1 [ref]

0

 Secondary level

3.64 [3.58 - 3.7]

<0.000001

4.01 [3.9 - 4.13]

<0.000001

 Tertiary level

4.32 [4.23 - 4.41]

<0.000001

12.34 [11.87 - 12.82]

<0.000001

 Adult first line

1 [ref]

0

1 [ref]

0

 Adult.2nd.Line

0.7 [0.67 - 0.73]

<0.000001

0.09 [0.09 - 0.1]

0

 Adult.3rd.Line

0 [0 - 5.91e+14]

0.686815

0 [0 – 4.45e+20]

0.702157

 Peds.1st.Line

1.26 [1.23 - 1.3]

<0.000001

0.35 [0.32 - 0.39]

<0.000001

 Peds.2nd.Line

0.54 [0.44 - 0.65]

<0.000001

0.08 [0.06 - 0.1]

<0.000001

 Salvage

0.34 [0.1 - 1.14]

0.079702

0.02 [0 - 0.06]

<0.000001

 1

1 [ref]

0

1 [ref]

0

 2

0.7 [0.67 - 0.73]

<0.000001

0.78 [0.76 - 0.81]

<0.000001

 3-5

0.1 [0.09 - 0.1]

<0.000001

0.02 [0.02 - 0.02]

<0.000001

 6

0.04 [0.03 - 0.04]

<0.000001

0.01 [0 - 0.01]

<0.000001

 Suppressed

1 [ref]

0

1 [ref]

0

 Not recorded

7.1 [6.89 - 7.32]

<0.000001

10.02 [9.76 – 10.28]

<0.000001

 Unsuppressed

1.99 [1.9 - 2.09]

<0.000001

2.23 [2.14 - 2.33]

<0.000001