Table 3 Univariable and multivariable Cox proportional hazards analysis of the training set

Female

1.364 (0.686,2.712)

0.376

Marital Status (Married)

0.83 (0.496,1.388)

0.478

 Homosexual transmission

Ref

Ref

Ref

Ref

 Heterosexual transmission

1.551 (0.984,2.446)

0.059#

1.327 (0.821, 2.145)

0.248

 Other transmission

1.979 (1.142,3.428)

0.015*

1.193 (0.661, 2.154)

0.478

Baseline TB

2.024 (0.821,4.986)

0.125#

1.264 (0.491, 3.255)

0.584

HBV (Negative)

0.619 (0.227,1.689)

0.349

HCV (Negative)

0.702 (0.098,5.04)

0.725

Continuous diarrhea (> one month)

2.478 (1.286,4.775)

0.007*

2.271 (1.088, 4.742)

0.058

Continuous or intermittent fever

2.028 (1.141,3.605)

0.016*

0.905 (0.448, 1.680)

0.628

Shingles

1.905 (1.138,3.187)

0.014*

1.965 (1.140, 3.390)

0.018*

 I, II

Ref

Ref

–

–

 III

1.572 (0.908,2.721)

0.106#

–

–

 IV

2.692 (1.678,4.318)

< .001***

–

–

Age, year

1.007 (0.99,1.023)

0.424

Interval from onset to diagnosis, day

1.000 (1.000,1.000)

0.564

CD4, cells/μL

0.995 (0.994,0.997)

< .001***

0.996 (0.995, 0.0.998)

< .001***

BMI, kg/m2

0.795 (0.74,0.853)

< .001***

0.875 (0.809, 0.946)

< .001***

WBC, 10⁹/L

0.969 (0.888,1.057)

0.476

PLT, 10⁹/L

0.998 (0.995,1.001)

0.254

HB, g/L

0.968 (0.961,0.975)

< .001***

0.975 (0.965, 0.984)

< .001***

CR, μmol/L

1.002 (1,1.005)

0.099#

1.002 (0.999, 1.005)

0.175

TG, mmol/L

0.963 (0.849,1.093)

0.562

TC, mmol/L

0.707 (0.57,0.877)

0.002*

0.821 (0.670, 1.006)

0.038*

FBG, mmol/L

0.731 (0.59,0.905)

0.004*

0.938 (0.769, 1.145)

0.442

AST, U/L

1.011 (1.006,1.017)

< .001***

1.001 (0.989, 1.014)

0.951

ALT, U/L

1.008 (1.002,1.014)

0.008*

1.002 (0.992, 1.012)

0.647

TBIL, mmol/L

0.991 (0.957,1.027)

0.617