Table 5 Risk ratios for non-completion of treatment among individuals who started treatment for latent tuberculosis infection at the TB Clinic between January 2010 to December 2016. Risk ratios marked with an asterisk (*) are statistically significant. CI= confidence interval
Potential Risk Factors | Non-completion /category total (%) | Unadjusted risk ratio (95% CI) | Adjusted risk ratio (95% CI) n = 408 patientsa |
|---|---|---|---|
Age, years (per 5-year increase) | - | 0.99 (0.97-1.02) | 1.00 (0.97-1.03) |
Sex | |||
Male | 181/576 (31.4%) | Reference | Reference |
Female | 227/627 (36.2% | 1.15 (0.98-1.35) | 1.13 (0.97-1.32) |
Reason for referral | |||
Rule out active TB | 90/266 (33.8%) | Reference | Reference |
Employment screen | 100/268 (37.3%) | 1.10 (0.88-1.39) | 1.01 (0.81-1.26) |
Health science school screen | 27/83 (32.5%) | 0.96 (0.67-1.37) | 0.87 (0.62-1.22) |
Contact | 99/277 (35.7%) | 1.06 (0.84-1.33) | 1.00 (0.80-1.24) |
Immunosuppressive therapy | 71/227 (31.3%) | 0.92 (0.71-1.19) | 0.90 (0.70-1.16) |
Immigration surveillance | 21/82 (25.6%) | 0.76 (0.50-1.13) | 0.90 (0.60-1.35) |
Year of consultation | |||
2010 | 49/191 (25.7%) | 0.71 (0.51-0.99)* | 0.84 (0.60-1.18) |
2011 | 57/199 (28.6%) | 0.79 (0.58-1.09) | 0.91 (0.66-1.26) |
2012 | 60/159 (37.7%) | 1.04 (0.77-1.41) | 1.08 (0.81-1.44) |
2013 | 56/172 (32.6%) | 0.90 (0.66-1.23) | 0.90 (0.67-1.22) |
2014 | 78/188 (41.5%) | 1.15 (0.87-1.52) | 1.10 (0.84-1.44) |
2015 | 60/161 (37.2%) | 1.03 (0.76-1.40) | 1.02 (0.77-1.36) |
2016 | 48/133 (36.1%) | Reference | Reference |
Treatment regimen | |||
Isoniazid (9INH) | 278/685 (40.6%) | Reference | Reference |
Rifampin (4R) | 127/511 (24.9%) | 0.61 (0.51-0.73)* | 0.69 (0.58-0.84)* |
Moxifloxacin | 2/5 (40.0%) | 0.98 (0.33-2.89) | 1.15 (0.38-3.45) |
Referral back to primary care team | 136/248 (54.8%) | 1.92 (1.65-2.24)* | 1.59 (1.33-1.91)* |