Table 4 Adjusted odds ratios and 95% confidence intervals for the association between birth decade and history of sunburns and sunbed use among GenoMEL participants

 1910–1929

147

63 (42.9)

84 (57.1)

1.00

REF

144

130 (90.3)

14 (9.7)

1.00

REF

 1930–1939

351

147 (41.9)

204 (58.1)

1.07

(0.70 1.63)

349

292 (83.7)

57 (16.3)

 1940–1949

493

142 (28.8)

351 (71.2)

2.03

(1.28 3.22)

492

366 (74.4)

126 (25.6)

2.29

(1.48 3.53)

 1950–1959

501

132 (26.4)

369 (73.7)

2.20

(1.39 3.48)

497

353 (71.0)

144 (29.0)

3.05

(1.94 4.79)

 1960–1969

482

137 (28.4)

345 (71.6)

1.92

(1.10 3.35)

476

294 (61.8)

182 (38.2)

6.12

(3.78 9.89)

 1970–1979

292

113 (38.7)

179 (61.3)

1.12

(0.60 2.11)

289

173 (59.9)

116 (40.1)

6.36

(3.53 11.44)

 1980–1989

141

75 (53.2)

66 (46.8)

0.69

(0.32 1.46)

138

94 (68.1)

44 (31.9)

4.38

(2.12 9.07)

 Total

2407

809 (33.6)

1598 (66.4)

2385

1702 (71.4)

683 (28.6)

 Per Cohort OR

0.96

(0.86 1.08)

1.44

(1.28 1.62)

 P_trend

0.52

< 0.0001

 1910–1929

140

93 (66.4)

47 (33.6)

1.00

REF

*

 1930–1939

331

212 (64.0)

119 (36.0)

1.24

(0.78 1.99)

*

 1940–1949

467

270 (57.8)

197 (42.2)

1.68

(1.07 2.62)

*

 1950–1959

481

253 (52.6)

228 (47.4)

2.05

(1.32 3.17)

*

 1960–1969

464

276 (59.5)

188 (40.5)

1.57

(0.97 2.54)

*

 1970–1979

283

191 (67.5)

92 (32.5)

1.04

(0.62 1.73)

*

 1980–1989

139

108 (77.7)

31 (22.3)

0.71

(0.39 1.29)

*

 Total

2305

1403 (58.3)

902 (41.7)

 Per Cohort OR

0.96

(0.90 1.02)

 P_trend

0.21

 1910–1929

147

68 (46.3)

79 (53.7)

1.00

REF

*

 1930–1939

349

160 (45.9)

189 (54.1)

1.07

(0.71 1.61)

*

 1940–1949

493

165 (33.5)

328 (66.5)

1.88

(1.24 2.85)

*

 1950–1959

501

155 (30.9)

346 (69.1)

2.10

(1.42 3.12)

*

 1960–1969

479

146 (30.5)

333 (69.5)

2.27

(1.47 3.51)

*

 1970–1979

292

119 (40.8)

173 (59.2)

1.36

(0.87 2.13)

*

 1980–1989

141

76 (53.9)

65 (46.1)

0.94

(0.56 1.57)

*

 Total

2402

889 (36.9)

1513 (63.1)

 Per Cohort OR

1.04

(0.97 1.11)

 P_trend

0.30

 1910–1929

147

114 (77.6)

33 (22.4)

1.00

REF

 1930–1939

351

242 (69.0)

109 (31.0)

1.71

(1.04 2.83)

*

 1940–1949

491

278 (56.6)

213 (43.4)

3.13

(1.89 5.20)

*

 1950–1959

501

283 (56.5)

218 (43.5)

3.29

(1.97 5.49)

*

 1960–1969

482

297 (61.6)

185 (38.4)

2.82

(1.60 4.96)

*

 1970–1979

291

197 (67.7)

94 (32.3)

2.31

(1.24 4.29)

*

 1980–1989

106

82 (77.4)

24 (22.6)

1.47

(0.67 3.22)

*

 Total

2369

1493 (63.0)

876 (37.0)

*

 Per Cohort OR

1.05

(0.96 1.14)

 P_trend

0.33

 1910–1929

77

36 (46.8)

41 (53.3)

1.00

REF

74

67 (90.5)

7 (9.5)

1.00

REF

 1930–1939

164

71 (43.3)

93 (56.7)

1.08

(0.60 1.95)

163

199 (84.0)

39 (16.0)

 1940–1949

207

78 (37.7)

129 (62.3)

1.64

(0.94 2.86)

207

141 (68.1)

66 (31.9)

2.06

(1.19 3.55)

 1950–1959

268

74 (27.6)

194 (72.4)

2.60

(1.47 4.60)

266

178 (66.9)

88 (33.1)

2.11

(1.20 3.55)

 1960–1969

242

80 (33.1)

162 (66.9)

2.06

(1.17 3.65)

240

145 (60.4)

95 (39.6)

3.20

(1.89 5.41)

 1970–1979

189

81 (42.9)

108 (57.1)

1.19

(0.65 2.15)

189

110 (58.2)

79 (41.8)

3.20

(1.81 5.63)

 1980–1989

110

60 (54.6)

50 (45.4)

0.86

(0.44 1.68)

108

72 (66.7)

36 (33.3)

2.03

(1.09 3.77)

 Total

1257

480 (38.2)

777 (61.8)

1247

845 (67.8)

402 (32.2)

 Per Cohort OR

0.99

(0.91 1.08)

1.19

(1.09 1.30)

 P_trend

0.78

0.0002

 1910–1929

70

27 (38.6)

43 (61.4)

1.00

REF

70

63 (90.0)

7 (10.0))

1.00

REF

 1930–1939

187

76 (40.6)

111 (59.4)

1.10

(0.58 2.11)

186

160 (86.0)

26 (14.0))

 1940–1949

286

64 (22.4)

222 (77.6)

2.90

(1.48 5.66)

285

225 (79.0)

60 (21.0)

2.06

(1.17 3.64)

 1950–1959

233

58 (24.9)

175 (75.1)

2.44

(1.27 4.70)

231

175 (75.8)

56 (24.2)

2.73

(1.47 5.04)

 1960–1969

240

57 (23.8)

183 (76.2)

2.68

(1.21 5.93)

236

149 (63.1)

87 (36.9)

6.46

(3.47 12.05)

 1970–1979

103

32 (31.1)

71 (68.9)

1.89

(0.79 4.50)

100

63 (63.0)

37 (37.0)

5.80

(2.60 12.93)

 1980–1989

31

15 (48.4)

16 (51.6)

0.92

(0.29 2.92)

30

22 (73.3)

8 (26.7)

2.83

(0.81 9.94)

 Total

1150

329 (28.6)

821 (71.4)

1138

857 (75.3)

281 (24.7)

 Per Cohort OR

1.00

(0.99 1.02)

1.46

(1.24 1.71)

 P_trend

0.29

< 0.0001

OR_{cases vs non-cases}

1.12

(0.88 1.42)

0.89

(0.67 1.16)

P_{heterogeneity of trend}

0.21

0.21

 1910–1929

70

27 (38.6)

43 (61.4)

1.00

REF

70

65 (92.9)

5 (7.1)

1.00

REF

 1930–1939

187

77 (41.2)

110 (58.8)

183

163 (89.1)

20 (10.9)

 1940–1949

285

63 (22.1)

222 (77.9)

2.62

(1.69 4.05)

285

237 (83.2)

48 (16.8)

1.86

(1.05 3.29)

 1950–1959

232

57 (24.6)

175 (75.4)

2.16

(1.44 3.25)

226

182 (80.5)

44 (19.5)

2.26

(1.25 4.07)

 1960–1969

238

56 (23.5)

182 (76.5)

2.38

(1.50 3.77)

234

156 (66.7)

78 (33.3)

5.45

(3.26 9.10)

 1970–1979

101

31 (30.7)

70 (69.3)

1.68

(0.96 2.92)

99

64 (64.7)

35 (35.3)

4.98

(2.63 9.43)

 1980–1989

31

15 (48.4)

16 (51.6)

0.77

(0.34 1.78)

30

23 (76.7)

7 (23.3)

2.05

(0.64 6.58)

 Total

1144

326 (28.5)

818 (71.5)

1127

890 (79.0)

237 (21.0)

 Per Cohort OR

1.09

(0.98 1.21)

1.41

(1.25 1.59)

 P_trend

0.12

< 0.0001

 1910–1929

68

66 (97.1)

2 (2.9)

1.00

REF

70

68 (97.1)

2 (2.9)

1.00

REF

 1930–1939

184

176 (95.7)

8 (4.3)

187

181 (96.8)

6 (3.2)

 1940–1949

281

265 (94.3)

16 (5.7)

2.08

(0.83 5.26)

286

270 (94.4)

16 (5.6)

1.57

(0.64 3.88)

 1950–1959

226

199 (88.1)

27 (11.9)

4.40

(1.88 10.29)

233

222 (95.3)

11 (4.7)

1.33

(0.46 3.81)

 1960–1969

224

189 (84.4)

35 (15.6)

6.13

(2.60 14.43)

240

228 (95.0)

12 (5.0)

1.34

(0.59 3.04)

 1970–1979

95

81 (85.3)

14 (14.7)

5.80

(2.20 15.27)

102

97 (95.1)

5 (4.9)

1.24

(0.38 4.00)

 1980–1989

27

20 (74.1)

7 (25.9)

10.53

(3.24 34.29)

31

29 (93.6)

2 (6.5)

1.61

(0.30 8.60)

 Total

1105

996 (90.1)

109 (9.9)

1149

1095 (95.3)

54 (4.7)

 Per Cohort OR

1.53

(1.32 1.76)

1.03

(0.85 1.25)

 P_trend

< 0.0001

0.76

OR_{post vs pre}^c

0.04

(0.04 0.05)

0.19

(0.14 0.25)

P_{heterogeneity of trend}^c

< 0.0001

0.008