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Table 2 Age-standardized disability-adjusted life-years (DALY) rate (per 100,000) for 116 diseases in Hakka, Canton and Hoklo culture regions in 2005 and 2015

From: Age-standardized mortality, disability-adjusted life-years and healthy life expectancy in different cultural regions of Guangdong, China: a population-based study of 2005–2015

All cause of death

Hakka culture region

Canton culture region

Hoklo culture region

P value

2005

2015

Change

2005

2015

Change

2005

2015

Change

All cause of death

25,738.30

19,988.00

−22.34*

17,093.90

14,396.50

−15.78*

24,871.80

20,436.60

−17.83*

< 0.0001#

Communicable, maternal, neonatal, and nutritional diseases

2790.66

2666.13

−4.46*

1990.19

1803.29

−9.39*

2795.57

2515.09

−10.03*

< 0.0001#

HIV/AIDS and tuberculosis

330.86

358.49

8.35

196.40

179.54

−8.58*

383.21

388.06

1.27*

< 0.0001#

Tuberculosis

288.13

286.30

−0.64*

141.89

106.78

−24.74*

345.39

328.49

−4.89*

< 0.0001#

HIV/AIDS

42.73

72.19

68.94*

54.51

72.75

33.46*

37.83

59.57

57.47*

< 0.0001#

Diarrhoea, lower respiratory and other common infectious diseases

711.32

597.00

−16.07*

531.49

410.33

−22.80*

718.61

541.28

−24.68*

0.062

Diarrhoeal diseases

101.27

90.23

−10.90*

68.42

52.25

−23.63*

80.26

71.07

−11.45*

< 0.0001#

Intestinal infectious diseases

13.89

10.00

−28.01*

12.93

9.86

− 23.74*

13.76

8.45

−38.59*

0.724

Lower respiratory infections

164.06

259.81

58.36*

144.61

191.86

32.67*

155.69

229.19

47.21*

< 0.0001#

Meningitis

117.92

71.61

−39.27*

72.30

42.32

−41.47*

100.06

58.64

−41.40*

< 0.0001#

Measles

172.89

50.61

−70.73*

126.39

30.16

−76.14*

202.08

59.95

−70.33*

< 0.0001#

Neglected tropical diseases and malaria

520.70

400.65

−23.06*

337.72

271.49

−19.61*

417.23

357.02

−14.43*

< 0.0001#

Malaria

1.74

1.03

−40.80*

1.83

0.66

−63.93*

1.65

0.89

−46.06*

< 0.0001#

Rabies

28.54

6.61

−76.84*

26.22

12.07

−53.97*

19.93

5.70

−71.40*

< 0.0001#

Intestinal nematode infections

333.62

298.88

−10.41*

199.42

153.19

−23.18*

256.50

244.64

−4.62*

< 0.0001#

Maternal disorders

14.89

5.29

−64.47*

20.99

7.50

−64.27*

14.64

5.02

−65.71*

0.279

Neonatal disorders

614.72

732.54

19.17*

491.65

578.33

17.63*

625.34

654.49

4.66*

< 0.0001#

Nutritional deficiencies

474.19

490.59

3.46*

342.68

316.20

−7.73*

499.87

485.01

−2.97*

< 0.0001#

Iron-deficiency anaemia

422.28

436.27

3.31*

299.59

274.73

−8.30*

447.77

432.29

−3.46*

< 0.0001#

Other communicable, maternal,neonatal, and nutritional diseases

123.99

81.57

−34.21*

69.27

39.91

−42.38*

136.67

84.21

−38.38*

< 0.0001#

Sexually transmitted diseases excluding HIV

51.81

31.84

−38.54*

38.54

13.25

−65.62*

56.05

34.00

−39.34*

< 0.0001#

Hepatitis

47.47

24.63

−48.11*

20.43

16.04

−21.49*

55.10

27.38

−50.31*

< 0.0001#

Acute hepatitis A

11.93

10.25

−14.08*

7.32

5.21

−28.83*

12.38

10.68

−13.73*

0.062

Acute hepatitis B

26.53

10.32

−61.10*

8.40

7.69

−8.45*

32.73

11.99

−63.37*

< 0.0001#

Acute hepatitis C

3.17

1.26

−60.25*

1.75

0.57

−67.43*

3.29

1.60

−51.37*

< 0.0001#

Non-communicable diseases

19,758.00

15,582.50

−21.13*

13,383.90

11,525.90

−13.88*

19,227.10

16,256.30

−15.45*

< 0.0001#

Neoplasms

3948.53

2891.63

−26.77*

3194.09

2397.33

−24.94*

3941.57

3142.67

−20.27*

< 0.0001#

esophageal cancer

183.09

134.50

−26.54*

142.85

99.42

−30.40*

199.78

164.78

−17.52*

< 0.0001#

Stomach cancer

405.49

308.33

−23.96*

310.70

214.23

−31.05*

411.30

345.05

−16.11*

< 0.0001#

Liver cancer

802.96

551.27

−31.35*

590.71

395.57

−33.03*

763.51

584.75

−23.41*

0.001#

Tracheal, bronchus, and lung cancer

995.58

626.03

−37.12*

654.80

503.17

−23.16*

1005.01

668.99

−33.43*

< 0.0001#

Breast cancer

145.22

121.48

−16.35*

163.21

121.10

−25.80*

135.40

125.60

−7.24*

0.747

Cervical cancer

29.21

52.75

80.59*

48.78

72.70

49.04*

26.22

50.55

92.79*

0.010#

Uterine cancer

44.14

18.29

−58.56*

31.45

9.99

−68.24*

46.82

19.00

−59.42*

< 0.0001#

Prostate cancer

8.30

6.82

−17.83

8.20

6.31

−23.05*

8.55

7.84

−8.30

< 0.0001#

Colon and rectum cancer

156.54

169.17

8.07*

187.59

183.46

−2.20*

161.73

194.72

20.40*

< 0.0001#

Nasopharygeal cancer

315.14

206.17

−34.58*

286.20

176.43

−38.35*

327.84

239.86

−26.84*

< 0.0001#

Pancreatic cancer

58.98

67.11

13.78*

71.78

66.31

−7.62*

61.90

74.10

19.71*

< 0.0001#

Ovarian cancer

29.13

32.11

10.23*

45.56

39.85

−12.53

28.77

33.66

17.00*

< 0.0001#

Kidney cancer

20.87

19.51

−6.52*

27.22

21.81

−19.88*

22.51

23.18

2.98*

< 0.0001#

Bladder cancer

34.62

17.30

−50.03*

28.81

13.64

−52.66*

37.86

21.62

−42.89*

< 0.0001#

Thyroid cancer

20.16

13.61

−32.49*

21.45

12.54

−41.54*

18.19

13.46

−26.00*

0.273

Leukaemia

228.80

158.44

−30.75*

194.89

140.81

−27.75*

224.07

165.17

−26.29*

< 0.0001#

Cardiovascular diseases

4292.37

3093.99

−27.92*

2908.59

2274.07

−21.82*

4218.82

3249.63

−22.97*

< 0.0001#

Rheumatic heart disease

196.97

93.83

−52.36*

104.52

56.33

−46.11*

191.94

97.25

−49.33*

0.029#

Ischaemic heart disease

1372.88

1160.05

−15.50*

1152.25

1032.42

−10.40*

1310.31

1193.98

−8.88*

< 0.0001#

Cerebrovascular disease

2321.07

1478.05

−36.32*

1369.14

899.75

−34.28*

2337.35

1599.92

−31.55*

< 0.0001#

Ischaemic stroke

962.06

597.31

−37.91*

560.86

392.07

−30.09*

967.38

675.00

−30.22*

< 0.0001#

Haemorrhagic stroke

1359.01

880.74

−35.19*

808.29

507.69

−37.19*

1369.97

924.92

−32.49*

< 0.0001#

Hypertensive heart disease

171.87

164.18

−4.47*

145.62

154.92

6.39*

155.44

156.60

0.75*

< 0.0001#

Cardiomyopathy and myocarditis

67.02

56.00

−16.44*

31.45

28.65

−8.90*

64.62

55.30

−14.42*

0.001#

Atrial fibrillation and flutter

47.78

56.10

17.41*

35.69

44.47

24.60*

46.92

58.21

24.06*

< 0.0001#

Aortic aneurysm

29.87

25.59

−14.33

18.44

17.56

−4.77*

29.29

27.46

−6.25

< 0.0001#

Chronic respiratory diseases

1637.99

1000.40

−38.93*

904.81

545.24

−39.74*

1656.14

1041.28

−37.13*

< 0.0001#

Chronic obstructive pulmonary disease

1426.92

884.04

−38.05*

835.85

505.83

−39.48*

1449.62

937.06

−35.36*

< 0.0001#

Asthma

192.13

89.54

−53.40*

61.23

26.79

−56.25*

188.97

79.16

−58.11*

< 0.0001#

Cirrhosis

435.60

249.30

−42.77*

228.36

135.34

−40.73*

455.87

274.54

−39.78*

< 0.0001#

Cirrhosis due to alcohol use

0.75

0.82

9.33*

0.72

0.82

13.89*

0.77

0.88

14.29*

0.014#

Digestive diseases

396.72

278.26

−29.86*

199.95

149.06

−25.45*

384.09

289.64

−24.59*

< 0.0001#

Peptic ulcer disease

134.96

73.14

−45.81*

61.65

34.26

−44.43*

129.65

74.93

−42.21*

0.551

Pancreatitis

21.22

12.08

−43.07*

15.88

9.48

− 40.30*

23.23

14.37

−38.14*

< 0.0001#

Neurological disorders

736.75

699.57

−5.05*

668.45

631.02

−5.60*

725.72

698.53

−3.75*

< 0.0001#

Alzheimer’s disease and other dementias

159.18

171.88

7.98*

173.57

177.04

2.00*

159.87

174.48

9.14*

< 0.0001#

Parkinson’s disease

74.07

70.28

−5.12*

80.65

81.91

1.56*

73.22

71.84

−1.88*

< 0.0001#

Epilepsy

67.32

81.31

20.78*

64.49

78.07

21.06*

65.54

80.67

23.09*

< 0.0001#

hemicrania

307.23

264.57

−13.89*

240.39

199.87

−16.86*

300.10

259.84

−13.42*

< 0.0001#

Mental and substance use disorders

2731.12

2193.60

−19.68*

1022.46

960.20

−6.09*

2524.35

2177.44

−13.74*

< 0.0001#

Schizophrenia

346.57

539.44

55.65*

111.62

207.78

86.15*

303.54

579.32

90.85*

< 0.0001#

Drug use disorders

449.50

186.23

−58.57*

62.12

30.01

−51.69*

371.76

159.38

−57.13*

< 0.0001#

Depressive disorder 

778.66

604.07

−22.42*

287.74

242.16

−15.84*

729.79

566.76

−22.34*

< 0.0001#

infantile autism 

174.82

135.85

−22.29*

83.89

76.65

−8.63*

162.63

131.51

−19.14*

< 0.0001#

Diabetes, urogenital, blood, and endocrine diseases

1779.26

1384.84

−22.17*

1075.26

946.26

−12.00*

1665.06

1412.85

−15.15*

< 0.0001#

Diabetes mellitus

820.07

558.89

−31.85*

419.41

342.39

−18.36*

772.48

590.16

−23.60*

< 0.0001#

Chronic kidney disease

345.98

277.13

−19.90*

234.71

196.45

−16.30*

317.28

273.49

−13.80*

< 0.0001#

Gynaecological diseases

153.83

148.49

−3.47*

107.62

99.16

−7.86 *

144.09

150.96

4.77*

0.244

Haemoglobinopathies and haemolytic anaemias

283.33

259.98

−8.24*

174.98

179.36

2.50*

260.54

255.86

−1.80*

< 0.0001#

Musculoskeletal disorders

1694.31

1616.82

−4.57*

1481.89

1512.38

2.06*

1657.90

1760.05

6.16*

< 0.0001#

Rheumatoid arthritis

56.21

61.70

9.77*

46.44

55.64

19.81*

55.89

73.18

30.94*

< 0.0001#

Osteoarthritis

147.59

182.70

23.79*

126.18

165.03

30.79*

153.44

205.27

33.78*

< 0.0001#

Low back and neck pain

1068.61

1010.80

−5.41*

1019.89

1029.16

0.91*

1096.16

1155.43

5.41*

< 0.0001#

Low back pain

569.02

533.84

−6.18*

548.66

555.13

1.18*

583.39

611.18

4.76*

< 0.0001#

Neck pain

499.60

476.95

−4.53*

471.23

474.03

0.59*

512.77

544.25

6.14*

< 0.0001#

Other non-communicable diseases

2105.39

2174.14

3.27*

1700.02

1974.99

16.17*

1997.56

2209.71

10.62*

< 0.0001#

Congenital anomalies

584.40

672.16

15.02*

446.03

622.86

39.65*

547.95

676.35

23.43*

< 0.0001#

Skin and subcutaneous diseases

542.34

471.68

−13.03*

310.09

274.66

−11.43*

435.85

384.40

−11.80*

< 0.0001#

Sense organ diseases

795.19

848.91

6.76*

704.87

808.17

14.66*

834.64

956.11

14.55*

< 0.0001#

Oral disorders

179.49

175.50

−2.22*

140.20

152.86

9.03*

175.63

187.98

7.03*

< 0.0001#

Injuries

3189.58

1739.29

−45.47*

1719.80

1067.36

−37.94*

2849.14

1665.14

− 41.56*

< 0.0001#

Transport injuries

1362.87

692.02

−49.22*

734.36

417.83

−43.10*

1201.41

688.81

−42.67*

< 0.0001#

Road injuries

1262.68

650.63

−48.47*

709.54

398.92

−43.78*

1121.45

657.52

−41.37*

< 0.0001#

Other transport injuries

100.19

41.39

−58.69*

24.82

18.91

−23.81*

79.97

31.29

−60.87*

< 0.0001#

Unintentional injuries

1206.87

796.01

−34.04*

760.03

537.22

−29.32*

1050.09

721.60

−31.28*

< 0.0001#

Falls

351.26

288.25

−17.94*

237.65

208.51

−12.26*

306.90

269.26

−12.26*

< 0.0001#

Drowning

284.75

153.98

−45.92*

196.80

107.00

−45.63*

247.19

135.73

−45.09*

< 0.0001#

Fire, heat, and hot substances

84.61

40.09

−52.62*

37.98

21.51

−43.36*

71.74

33.44

−53.39*

< 0.0001#

Poisonings

108.29

49.18

−54.58*

49.20

23.83

−51.57*

93.20

43.87

−52.93*

< 0.0001#

Intentional injury

604.52

245.09

−59.46*

217.08

108.35

−50.09*

583.96

248.85

−57.39*

< 0.0001#

Self-harm and interpersonal violence

412.28

167.03

−59.49*

150.58

74.45

−50.56*

396.15

170.64

−56.93*

< 0.0001#

Interpersonal violence

192.24

78.05

−59.40*

66.50

33.90

−49.02*

187.81

78.22

−58.35*

< 0.0001#

Other diarrhea, lower respiratory and common infectious disease

141.29

114.75

−18.78*

106.84

83.87

−21.50*

166.76

113.99

−31.64*

< 0.0001#

Other neglected tropical disease

156.80

94.13

−39.97*

110.26

105.57

−4.25*

139.16

105.79

−23.98*

< 0.0001#

Other nutritional disease

51.91

54.32

4.64*

43.09

41.47

−3.76*

52.11

52.72

1.17*

< 0.0001#

Other hepatitis

5.84

2.79

−52.23*

2.97

2.57

−13.47*

6.70

3.12

−53.43*

< 0.0001#

Other Communicable, maternal, neonatal, and nutritional diseases

24.70

25.10

1.62*

10.30

10.62

3.11*

25.53

22.83

−10.58*

< 0.0001#

Other cancer

470.29

388.74

−17.34

379.87

319.99

−15.76*

462.12

410.32

−11.21

< 0.0001#

Other cardiovascular disease

84.91

60.18

−29.12*

51.47

39.97

−22.34*

82.94

60.89

−26.59*

< 0.0001#

Other chronic respiratory disease

18.93

26.83

41.73*

7.73

12.62

63.26*

17.56

25.06

42.71*

< 0.0001#

Oother Cirrhosis

434.85

248.48

−42.86*

227.64

134.52

−40.91*

455.10

273.65

−39.87*

< 0.0001#

Other digestive disease

240.54

193.04

−19.75*

122.43

105.32

−13.98*

231.21

200.34

−13.35*

< 0.0001#

Other Neurological disorders

128.95

111.54

−13.50*

109.35

94.14

−13.91*

126.99

111.71

−12.03*

< 0.0001#

Other mental and substance use disorders

981.56

728.01

−25.83*

477.09

403.61

−15.40*

956.63

740.48

−22.59*

< 0.0001#

Other diabetes, urogenital, blood, and endocrine diseases

176.05

140.34

−20.28*

138.54

128.90

−6.96

170.67

142.38

−16.58*

0.007#

Other Musculoskeletal disorders

421.90

361.62

−14.29

289.38

262.56

−9.27*

352.41

326.18

−7.44

< 0.0001#

Others

3.97

5.89

48.36*

98.84

116.44

17.81

3.49

4.87

39.54*

< 0.0001#

Other unintentional injury

377.97

264.52

−30.02*

238.41

176.36

−26.03*

331.06

239.31

−27.71*

< 0.0001#

Other injury

15.32

6.18

−59.66*

8.33

3.96

−52.46*

13.68

5.88

−57.02*

< 0.0001#

  1. *Statistical significance using the test of Cochran-Armitage trend for year 2005 to 2015 comparison (P < 0.05); #statistical significance using Poisson regression model for comparison of different culture regions (P < 0.05)