Table 2 Main outcome means, standard deviation or percent with associated effect sizes (Cohen’s d’ or Odds Ratio)

 Baseline

1.27 (0.32)

1.32 (0.24)

3.00 (0.59)

0.30 (0.35)

3.43 (1.88)

25.16%

 12 months

1.16 (0.21)

1.21 (0.21)

3.02 (0.54)

0.52 (0.34)

3.76 (1.58)

35.24%

 24 months

1.16 (0.22)

1.21 (0.21)

3.00 (0.54)

0.52 (0.33)

3.76 (1.54)

31.36%

 Baseline

1.25 (0.32)

1.33 (0.27)

2.93 (0.57)

0.28 (0.32)

3.08 (1.63)

30.00%

 12 months

1.17 (0.28)

1.24 (0.24)

3.02 (0.53)

0.62 (0.32)

3.72 (1.60)

30.47%

 24 months

1.16 (0.28)

1.24 (0.24)

3.01 (0.52)

0.62 (0.33)

3.69 (1.61)

30.00%

 Baseline

1.29 (0.33)

1.36 (0.28)

2.85 (0.55)

0.28 (0.31)

3.00 (1.76)

38.96%

 12 months

1.16 (0.25)

1.26 (0.25)

3.07 (0.55)

0.61 (0.31)

3.82 (1.61)

29.66%

 24 months

1.16 (0.24)

1.25 (0.24)

3.09 (0.55)

0.60 (0.31)

3.82 (1.61)

28.46%

 Group by time Interaction

χ² = 2.22

p = .695

χ² = 0.96

p = .915

χ² = 10.56

p = .032

χ² = 16.54

p = .002

χ² = 6.27

p = .180

χ² = 12.33

p = .015

 Effect size PFP only vs. RFR only

d’ = 0.08

d’ = 0.04

d’ = 0.14

d’ = 0.39

d’ = 0.16

OR = .216

 Effect size PFP only vs. RFR + PFP

d’ = − 0.05

d’ = − 0.03

d’ = 0.38

d’ = 0.31

d’ = 0.28

OR = .549