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Table 3 Family members characteristics by intervention groups through the study

From: Effect of a family and interdisciplinary intervention to prevent T2D: randomized clinical trial

Anthropometric Characteristics

Individual Group

(n = 33)

Familiar Group

(n = 68)

Basal (n = 33)

Month 6 (n = 13)

Month 12 (n = 7)

Basal (n = 68)

Month 6 (n = 36)

Month 12 (n = 23)

Weight (kg)

72.0 ± 17.0

66.4 ± 16.0

75.0 ± 16.0C

68.6 ± 17.0

68.5 ± 16.0

65.4 ± 16.8

BMI (kg/m2)

26.3 ± 5.4

25.0 ± 5.4

28.4 ± 5.2C

25.9 ± 5.2

26.3 ± 5.3

25.5 ± 5.3

WC (cm)

86.0 ± 12.6

82.6 ± 11.8B

88.7 ± 11.2

83.6 ± 17.2

83.9 ± 11.8

78.8 ± 17.3

Body fat (%)

29.0 ± 11.0

28.2 ± 11.7

30.8 ± 13.0C

28.3 ± 9.0

28.6 ± 10.1

28.9 ± 10.1

Visceral Index (AU)

5.5 ± 4.0

4.7 ± 3.3

5.4 ± 3.9

6.3 ± 4.6

6.4 ± 4.6

5.0 ± 3.7

SBP (mm Hg)

108 ± 10

109 ± 10

111 ± 7

108 ± 14

110 ± 10

111 ± 13

Biochemistry Characteristics

Glucose (mg/dl)

0 min

89 ± 8.0

91 ± 10

88 ± 7

92 ± 9.0

90 ± 10

93 ± 10

Glucose (mg/dl)

120 min

106 ± 22

Not done

104 ± 29

102 ± 19

Not done

100 ± 22

AUCgluc_OGTT (mg/dl/min)

14,262 ± 2342

Not done

14,556 ± 2410

13,691 ± 2534

Not done

13,966 ± 2679

Tg (mg/dl)

103 ± 38

118 ± 36

108 ± 40

123 ± 58

128 ± 65

112 ± 62

Total Cholesterol (mg/dl)

167 ± 29

161 ± 30

180 ± 39∆I

174 ± 38

167 ± 38

159 ± 30∆I

HDL (mg/dl)

45 ± 11

50 ± 14

46 ± 12

44 ± 12

43 ± 11

50 ± 11

LDL (mg/dl)

102 ± 28

87 ± 28

112 ± 38C, ∆I

104 ± 32

102 ± 30E

90 ± 29F, ∆I

Markers of insulin resistance and B cell function

Matsuda Index

6.3 ± 3.9

Not done

4.6 ± 3.5

5.2 ± 3.2

Not done

5.5 ± 2.6

HOMA IR

1.8 ± 0.9

Not done

2.4 ± 1.0

2.3 ± 1.4

Not done

2.4 ± 1.8

Insulin secretion

0.47 ± 0.25 A

Not done

0.75 ± 0.38

0.66 ± 0.35 A

Not done

0.60 ± 0.33

Disposition Index

2.38 ± 0.75

Not done

2.64 ± 0.55

2.68 ± 0.86

Not done

2.62 ± 0.87

  1. Data presented as means ± standard deviation. A = p < 0.05 for comparison between groups at the corresponding time; B = p < 0.05 basal vs month 6 individual group; C = p < 0.05 basal vs month 12 individual group; D = p < 0.05 month 6 vs month 12 individual group; E = p < 0.05 basal vs month 6 familiar group; F = p < 0.05 basal vs month 12 familiar group; G = p < 0.05 month 6 vs month 12 familiar group; ∆H = p < 0.05 for comparison of change between groups from 0 to 6 months; ∆I = p < 0.05 for comparison of change between groups from 0 to 12 months. AU, arbitrary units; AUCgluc_OGTT, area under the glucose curve during oral glucose tolerance test; AUCIns, area under the insulin curve; BMI, body mass index; HbA1c, Glycated hemoglobin; HDL, high density lipoprotein; HOMA IR, homeostatic model assessment; IR, insulin resistance; LDL, low density lipoprotein; SBP, systolic pression blood; Tg, triglycerides; WC, waist circumference