|
Variable
|
Age
|
|---|
|
40-49 years (n=17,093)
|
50-59 years (n=25,373)
|
60–79 years (n=1542)
|
P for Trenda
|
|---|
|
Age (years)
|
44.6±2.3
|
51.7±2.0
|
66.1±3.5
|
< 0.01
|
|
Sex
|
|
Male
|
7111 (45.8)
|
1776 (44.4)
|
803 (48.9)
|
0.29
|
|
Female
|
8416 (55.2)
|
2227 (55.6)
|
839 (51.1)
| |
|
Systolic BP (mm Hg)
|
106.3±7.2
|
106.6±7.1
|
107.1±7.2
|
< 0.01
|
|
Diastolic BP (mm Hg)
|
66.6±5.9
|
67.2±5.9
|
66.6±6.1
|
< 0.01
|
|
Body mass index (kg/m2)
|
22.8±2.5
|
23.1±2.5
|
22.7±2.8
|
< 0.01
|
|
Fasting glucose (mg/dl)
|
90.4±24.0
|
91.5±18.8
|
93.7±25.2
|
< 0.01
|
|
Pulse pressure (mm Hg)
|
39.7±6.3
|
39.7±6.3
|
40.5±6.8
|
< 0.01
|
|
Total cholesterol (mg/dl)
|
188.7±33.7
|
198.0±35.6
|
197.3±36.0
|
< 0.01
|
|
Aspartate aminotransferase (U/L)
|
23.0±15.8
|
24.4±12.7
|
26.2±17.7
|
< 0.01
|
|
Alanine aminotransferase (U/L)
|
21.6±19.2
|
22.9±22.0
|
21.4±11.7
|
< 0.01
|
|
Gamma GTP (U/L)
|
25.1±27.6
|
26.6±26.8
|
24.7±31.7
|
< 0.01
|
|
Hemoglobin (g/dl)
|
13.6±1.6
|
13.6±1.4
|
13.5±1.4
|
< 0.01
|
|
Smoking status
|
|
No
|
11,880 (79.1)
|
3121 (81.1)
|
1312 (82.8)
|
< 0.01
|
|
Current
|
3138 (20.9)
|
725 (18.9)
|
272 (17.2)
| |
|
Drinking frequency
|
|
1–2/week
|
14,423 (94.2)
|
3657 (93.2)
|
1431 (89.4)
|
< 0.01
|
|
3–5/week
|
882 (5.8)
|
268 (6.8)
|
169 (10.6)
| |
|
Exercise frequency
| | | |
0.19
|
|
not at all
|
12,160 (79.9)
|
3103 (79.3)
|
1315 (82.2)
| |
|
3–5/ week
|
3059 (20.1)
|
808 (20.7)
|
285 (17.8)
| |
|
History of diabetes
| | | |
< 0.01
|
|
No
|
15,358 (98.9)
|
3921 (98.0)
|
1578 (96.1)
| |
|
Yes
|
169 (1.1)
|
82 (2.1)
|
64 (3.9)
| |
|
Family history of hypertension
| | | |
< 0.01
|
|
No
|
13,106 (93.0)
|
3406 (93.7)
|
1406 (96.6)
| |
|
Yes
|
979 (7.0)
|
231 (6.3)
|
50 (3.4)
| |
|
Family history of diabetes
| | | |
< 0.01
|
|
No
|
12,945 (91.8)
|
3368 (92.6)
|
1405 (96.5)
| |
|
Yes
|
1158 (8.2)
|
268 (7.4)
|
51 (3.5)
| |
- Values are expressed as mean ± SD (standard deviation) or number (percentage)
- aP for trend: Cochran-Armitage test for categorical variables and ANOVAs for continuous variables
