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Table 3 Development of person-time and PLHIV with viral suppression and viremia for PLHIV after ART initiation between 1999 and 2018, based on our longitudinal model (3a) and using the most recent VL in each year (3b)

From: Everything counts - a method to determine viral suppression among people living with HIV using longitudinal data for the HIV care continuum - results of two large, German, multi-center real-life cohort studies over 20 years (1999–2018)

People who ever initiated ART

Longitudinal model

Conventional method

 

Year

Viral suppression (< 50)

50 - < 200

200 - < 500

500 - < 1000

1000 - < 10,000

10,000 - < 100,000

100,000 - < 1,000,000

> 1,000,000

Year

Viral suppression (< 50)

50 - < 200

200 - < 500

500 - < 1000

1000 - < 10,000

10,000 - < 100,000

100,000 - < 1,000,000

> 1,000,000

Difference in viral suppression between the methods

1999

33.6

13.4

10.5

5.2

14.0

14.5

8.4

0.4

1999

51.7

9.4

7.4

3.6

12.2

9.9

5.3

0.5

18.1

2000

52.8

10.9

6.9

3.9

9.7

10.5

5.1

0.2

2000

62.2

7.6

3.4

2.7

10.7

8.5

4.4

0.5

9.4

2001

59.1

8.7

5.2

3.3

9.5

9.5

4.4

0.3

2001

64.2

7.5

3.9

3.1

8.7

8.5

3.9

0.2

5.2

2002

61.6

8.3

4.8

2.9

8.6

9.4

4.4

0.2

2002

64.2

7.3

3.5

2.8

8.7

8.6

4.5

0.4

2.6

2003

65.3

7.3

3.5

2.0

7.7

9.1

4.7

0.2

2003

68.6

5.6

3.2

2.1

7.1

8.7

4.6

0.2

3.3

2004

65.2

7.9

3.5

2.2

7.0

9.6

4.5

0.2

2004

67.1

7.1

2.9

2.0

7.6

8.6

4.3

0.3

1.9

2005

68.2

7.7

3.4

2.0

6.3

8.4

3.8

0.1

2005

69.1

7.2

3.4

2.3

6.5

7.8

3.6

0.1

0.8

2006

71.3

7.9

3.1

1.8

6.2

7.0

2.5

0.2

2006

74.6

6.3

3.2

1.8

5.4

6.4

2.1

0.1

3.3

2007

74.1

8.1

2.8

1.7

5.1

6.1

2.0

0.1

2007

75.5

7.4

3.1

1.9

4.9

5.2

1.8

0.2

1.4

2008

77.2

7.6

2.6

1.4

4.2

5.0

2.0

0.1

2008

78.9

6.1

2.9

1.6

4.3

4.1

2.0

0.2

1.8

2009

79.1

7.2

2.2

1.3

3.7

4.6

1.7

0.1

2009

80.2

6.2

2.5

1.6

3.5

4.0

1.8

0.2

1.1

2010

80.6

7.4

2.2

1.2

3.1

4.0

1.4

0.1

2010

83.2

5.7

2.4

1.3

3.1

3.0

1.2

0.1

2.7

2011 a

82.9

7.3

1.9

1.1

2.6

2.8

1.2

0.1

2011

85.1

6.0

1.7

1.1

2.4

2.3

1.3

0.1

2.2

2012

84.3

6.7

1.9

1.0

2.4

2.6

1.0

0.1

2012

85.8

5.3

2.0

1.2

2.2

2.3

1.0

0.1

1.5

2013

85.5

6.1

1.7

1.0

2.2

2.4

1.0

0.1

2013

87.7

5.1

1.8

0.9

1.8

1.8

1.0

0.1

2.2

2014

88.9

4.8

1.2

0.7

1.7

2.0

0.6

0.1

2014

90.7

3.7

1.2

0.6

1.4

1.7

0.6

0.1

1.8

2015 b

90.4

3.8

1.0

0.6

1.7

1.8

0.6

0.1

2015

91.9

3.2

0.9

0.6

1.3

1.4

0.6

0.1

1.4

2016

90.3

4.3

0.9

0.6

1.6

1.6

0.6

0.1

2016

91.6

3.6

0.9

0.4

1.2

1.5

0.5

0.1

1.3

2017

92.3

3.6

0.8

0.5

1.2

1.1

0.5

0.1

2017

93.0

3.2

0.8

0.4

1.0

0.9

0.5

0.1

0.7

2018

93.0

3.3

0.8

0.3

1.1

0.9

0.5

0.1

2018

93.3

3.2

0.9

0.3

0.9

0.9

0.4

0.1

0.3

  1. a The UNAIDS target of viral suppression using the longitudinal model with VL < 200 copies/ml has been met for PLHIV after ART initiation in the study population in Germany since 2011
  2. b The UNAIDS target of viral suppression using the longitudinal model with VL < 50 copies/ml has been met for PLHIV after ART initiation in the study population in Germany since 2015