Table 3 Associations with PrEP nonadherence in the past 4 days: Univariate and multivariate logistic regression

Age ≥ 35

65 (57.5%)

15 (53.6%)

0.85 (0.37–1.96)

.706

Race/Ethnicity = white

73 (64.6%)

16 (57.1%)

0.73 (0.32–1.70)

.465

Education = completed college/university

89 (78.8%)

25 (89.3%)

2.25 (0.63–8.08)

.215

Annual household income ≥ CAD $100,000

51 (47.2%)

12 (46.2%)

0.96 (0.41–2.26)

.922

Employed full-time

92 (81.4%)

22 (78.6%)

0.84 (0.30–2.32)

.732

Taking PrEP for ≥12 months

56 (49.6%)

15 (53.6%)

1.17 (0.51–2.69)

.704

Currently have a steady partner

43 (38.1%)

12 (42.9%)

1.22 (0.53–2.83)

.641

Condomless sex with any HIV-negative partners – past 3 months

90 (81.8%)

19 (70.4%)

0.53 (0.20–1.38)

.191

Condomless sex with any HIV status unknown partners – past 3 months

73 (67.0%)

15 (55.6%)

0.62 (0.26–1.45)

.269

Condomless sex with any HIV positive partners – past 3 months

46 (41.4%)

16 (59.3%)

2.06 (0.87–4.84)

.099

2.22 (0.89–5.56)

.089

Alcohol Consumption (AUDIT)

.096

.044

 Low risk

81 (71.7%)

15 (53.6%)

Ref

Ref

 Hazardous

27 (23.9%)

9 (32.1%)

1.80 (0.71–4.58)

.217

1.54 (0.57–4.18)

.399

 Harmful

5 (4.4%)

4 (14.3%)

4.32 (1.04–17.97)

.044

6.72 (1.49–30.33)

.013

Cannabis - moderate/high risk use (NIDA M-ASSIST)

35 (31.0%)

9 (32.1%)

1.06 (0.44–2.57)

.905

Cocaine - moderate/high risk use (NIDA M-ASSIST)

11 (9.7%)

7 (25.0%)

3.09 (1.07–8.90)

.037

3.11 (1.01–9.59)

.049

Inhalants - moderate/high risk use (NIDA MASSIST)

6 (5.3%)

4 (14.3%)

2.97 (0.78–11.36)

.111

Sedatives - moderate/high risk use (NIDA MASSIST)

6 (5.3%)

3 (10.7%)

2.14 (0.50–9.15)

.305

Any substance - moderate/high risk use (NIDA MASSIST)

46 (40.7%)

15 (53.6%)

1.68 (0.73–3.86)

.221

Currently experiencing depression (CESD-10)

25 (22.5%)

8 (28.6%)

1.38 (0.54–3.50)

.503

Received treatment for depression – past 3 months

22 (21.6%)

3 (12.0%)

0.50 (0.14–1.81)

.289