Table 2 Baseline characteristics of the 582 patients diagnosed with cirrhosis. Marital and employment status
Marital status, n (%) | P-value | Employment status, n (%) | P-value | Total, n (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Married 339 (58) | Never married 141 (24) | Prev. married 102 (18) | < 0.0001 | Employed 171 (29) | Pensioner 273 (47) | Disability retired 93 (16) | Unemployed 45 (8) | < 0.0001 | 582 (100) | |
Male | 213 (63) | 100 (71) | 55 (54) | 0.025 | 118 (69) | 165 (60) | 54 (58) | 31 (69) | 0.168 | 368 (63) |
Female | 126 (37) | 41 (29) | 47 (46) | 0.025 | 53 (31) | 108 (40) | 49 (42) | 14 (31) | 0.168 | 214 (37) |
Median age | 65 | 64 | 71 | < 0.0001 | 49 | 72 | 63 | 55 | < 0.0001 | 66 |
(10–90 percentile) | (51–80) | (48–81) | (55–86) | (46–69) | (66–84) | (51–77) | (39–62) | (50–81) | ||
Aetiologies | ||||||||||
Alcohol | 176 (52) | 73 (52) | 46 (45) | 0.083 | 96 (56) | 130 (48) | 47 (51) | 22 (49) | < 0.0001 | 295 (51) |
Cryptogenic | 50 (15) | 17 (12) | 16 (16) | 0.083 | 9 (5) | 66 (24) | 8 (9) | 0 (0) | < 0.0001 | 83 (14) |
Hepatitis C | 36 (11) | 30 (21) | 14 (14) | 0.083 | 31 (18) | 7 (3) | 24 (26) | 18 (40) | < 0.0001 | 80 (14) |
PBC | 21 (6) | 2 (1) | 8 (8) | 0.083 | 11 (6) | 16 (6) | 4 (4) | 0 (0) | < 0.0001 | 31 (5) |
NAFLD | 16 (5) | 9 (6) | 4 (4) | 0.083 | 5 (3) | 18 (7) | 6 (6) | 0 (0) | < 0.0001 | 29 (5) |
AIH | 18 (5) | 5 (4) | 7 (7) | 0.083 | 8 (5) | 20 (7) | 1 (1) | 1 (2) | < 0.0001 | 30 (5) |
Other causes | 22 (6) | 5 (4) | 7 (7) | 0.083 | 11 (6) | 16 (6) | 3 (3) | 4 (9) | < 0.0001 | 34 (6) |
Comorbidities | ||||||||||
Arterial hypertension | 123 (36) | 36 (26) | 29 (28) | 0.047 | 57 (33) | 90 (33) | 35 (38) | 6 (13) | 0.033 | 188 (32) |
CAD | 59 (17) | 22 (16) | 24 (24) | 0.254 | 17 (10) | 61 (22) | 26 (28) | 1 (2) | < 0.0001 | 105 (18) |
Diabetes mellitus | 109 (32) | 28 (20) | 30 (29) | 0.025 | 48 (28) | 83 (30) | 30 (32) | 6 (13) | 0.103 | 167 (29) |
Obesitya | 81 (24) | 37 (26) | 16 (16) | 0.010 | 46 (27) | 55 (20) | 23 (25) | 10 (22) | 0.473 | 134 (23) |
Severityb | ||||||||||
MELD (median) | 11 | 13 | 10 | 0.161 | 10 | 11 | 12 | 13 | 0.156 | 11 |
< 10 | 121 (36) | 47 (33) | 44 (43) | 0.041 | 80 (47) | 88 (32) | 31 (33) | 13 (29) | 0.050 | 212 (36) |
10–14 | 93 (27) | 29 (21) | 17 (17) | 0.041 | 31 (18) | 73 (27) | 24 (26) | 11 (24) | 0.050 | 139 (24) |
≥ 15 | 108 (32) | 61 (43) | 36 (35) | 0.041 | 57 (33) | 90 (33) | 37 (40) | 21 (47) | 0.050 | 205 (35) |
Child-Pugh class | ||||||||||
A | 134 (40) | 42 (30) | 34 (33) | 0.172 | 82 (48) | 80 (29) | 37 (40) | 11 (24) | 0.001 | 210 (36) |
B | 125 (37) | 58 (41) | 41 (40) | 0.172 | 46 (27) | 121 (44) | 36 (39) | 21 (47) | 0.001 | 224 (38) |
C | 62 (18) | 37 (26) | 22 (22) | 0.172 | 40 (23) | 49 (18) | 19 (20) | 13 (29) | 0.001 | 121 (21) |
Complications | ||||||||||
Ascites | 151 (45) | 73 (52) | 51 (50) | 0.292 | 67 (39) | 147 (54) | 39 (42) | 22 (49) | 0.016 | 275 (47) |
Variceal bleeding | 21 (6) | 7 (5) | 4 (4) | 0.643 | 10 (6) | 14 (5) | 4 (4) | 4 (9) | 0.714 | 32 (6) |
Encephalopathy | 18 (5) | 15 (11) | 10 (10) | 0.075 | 13 (8) | 16 (6) | 9 (10) | 5 (11) | 0.463 | 43 (7) |
HCC | 45 (13) | 18 (13) | 11 (11) | 0.803 | 12 (7) | 45 (17) | 13 (14) | 4 (9) | 0.026 | 74 (13) |