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Table 5 Causal mediation analysis examining illicit drug use right before sex as a potential mediator between early sexual initiation and risky sexual practices among alcohol- and tobacco-using young adults in Taipei metropolitan area recruited using RDS during 2007–2010 (N = 916)

From: Early sexual initiation and risky sexual practices among alcohol- and tobacco-using young adults in Taiwan: mediation analysis of preceding-sex use of illicit drugs

Exposure (E)

Mediating variable (M)

Outcome variable (Y)

Direct effect

Indirect effect

Total effect

Indirect/Total (%)a

Early sexual initiation

Illicit drug use right before sex

Multiple sexual partners

1.61 (1.15–2.21)b

1.10 (1.03–1.23)b

1.77 (1.24–2.41)b

16.7

 

Casual sex

1.35 (1.08–1.67)b

1.07 (1.03–1.15)b

1.44 (1.17–1.77)b

18.6

 

Group sex

2.41 (1.23–4.87)b

1.19 (1.04–1.49)b

2.86 (1.46–5.37)b

16.6

 

Rare condom use

1.33 (0.92–1.85)

0.99 (0.94–1.02)

1.31 (0.91–1.81)

−3.72

  1. a Calculated on the natural log-scale
  2. bStatistically significant based on bootstrap 95% confidence intervals (in parenthesis)
  3. (1) All models controlled for male gender, age, education < college, employment, living with marital or romantic partner, and homosexual/bisexual experience, (2) Poisson regression was used for the outcome regression model (E and M predicting Y) for multiple sexual partners, casual sex, and rare condom use due to nonrare outcomes (prevalence > 10%). Logistic regression was used for group sex (prevalence < 10%)