Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysis

Reece, Albert Stuart; Hulse, Gary Kenneth

doi:10.1186/s12889-020-09748-5

Table 1 Spatial panel general method of moments regression – final models

From: Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysis

General	Parameters			Model
Instrumental Variables	Parameter	Estimate (95%C.I.)	P-Value	Para-meters	Value	P-Value
	Any Mental Illness
NHWhite_Score	spgm (amiyr ~ Cigarettes Cannabis * Alcohol_Abuse + Cocaine + Med_HH_Income + 5_Races)*
NHBlack_Score	Cigarettes: Cannabis: Alcohol_Abuse	−0.05 (− 0.07--0.03)	2.5E-05	rho	− 0.5152	N/A
Hispanic_Score	Cigarettes: Alcohol_Abuse	0.11 (0.06–0.16)	4.6E-05	sigma^2_	0.003	N/A
NHAsian_Score	Cannabis: Alcohol_Abuse	1.21 (0.61–1.81)	7.9E-05	lambda	0.6753	1.30E-05
NHAIAN_Score	Cigarettes: Cannabis	0.09 (0.05–0.13)	0.0001
	Alcohol_Abuse	−2.43 (−3.72--1.14)	0.0002
	Cigarettes	−0.17 (− 0.26--0.08)	0.0003
	Cannabis	−1.99 (−3.08--0.9)	0.0004
	Cocaine	0.05 (0.01–0.09)	0.0128
	Median_Household_Income	−0.03 (− 0.06–0)	0.0339
	Afr.Am_Pop_Fraction	0.03 (0–0.06)	0.0485
	Major Depressive Episode
NHWhite_Score	spgm (mde ~ Cigarettes Cannabis * Alcohol_Abuse + Cocaine + Med_HH_Income + 5_Races)*
NHBlack_Score	Cannabis: Alcohol_Abuse	1.74 (0.97–2.51)	9.9E-06	rho	−0.6813	N/A
Hispanic_Score	Cigarettes: Cannabis: Alcohol_Abuse	−0.07 (− 0.1--0.04)	2.6E-05	sigma^2	0.005	N/A
NHAsian_Score	Cannabis	−2.98 (− 4.38--1.58)	2.9E-05	lambda	0.8945	1.20E-04
NHAIAN_Score	Alcohol_Abuse	−3.46 (−5.1--1.82)	3.8E-05
	Cigarettes: Cannabis	0.12 (0.06–0.18)	6.3E-05
	Cigarettes: Alcohol_Abuse	0.13 (0.06–0.2)	8.1E-05
	Cigarettes	−0.23 (− 0.35--0.11)	2.4E-04
	Serious Mental Illness
NHWhite_Score	spgm (smiyr ~ Cigarettes Cannabis * Alcohol_Abuse + Cocaine + Med_HH_Income + 5_Races)*
NHBlack_Score	Cigarettes: Alcohol_Abuse	0.1 (0.03–0.17)	0.0048	rho	− 0.7386	N/A
Hispanic_Score	Cigarettes	−0.17 (− 0.29--0.05)	0.0058	sigma^2	0.0055	N/A
NHAsian_Score	Cigarettes: Cannabis: Alcohol_Abuse	−0.04 (− 0.07--0.01)	0.0082	lambda	0.7722	3.37E-07
NHAIAN_Score	Cocaine	0.07 (0.02–0.12)	0.0087
	Cigarettes: Cannabis	0.08 (0.02–0.14)	0.0092
	Alcohol_Abuse	−2.14 (−3.82--0.46)	0.0126
	Cannabis: Alcohol_Abuse	0.96 (0.17–1.75)	0.0169
	Cannabis	−1.66 (−3.09--0.23)	0.0231
NHWhite_Score	Suicidal Thoughts Past Year
NHBlack_Score	spgm (suithyr ~ Cigarettes Cannabis * Alcohol_Abuse + Cocaine + Med_HH_Income + 5_Races)*
Hispanic_Score	Alcohol_Abuse	−3.05 (− 4.67--1.43)	0.0002	rho	−0.6752	N/A
NHAsian_Score	Cannabis: Alcohol_Abuse	1.37 (0.61–2.13)	0.0004	sigma^2_	0.0051	N/A
NHAIAN_Score	Cigarettes: Alcohol_Abuse	0.12 (0.06–0.18)	0.0004	lambda	0.7757	7.96E-12
	Cigarettes: Cannabis: Alcohol_Abuse	−0.05 (− 0.08--0.02)	0.0012
	Cigarettes	−0.19 (− 0.31--0.07)	0.0016
	Cannabis	−2.18 (−3.55--0.81)	0.0019
	Cigarettes: Cannabis	0.08 (0.02–0.14)	0.0037

Abbreviations
5_Races: Caucasian-American, African-American, Hispanic-American, Asian-American, NHAIAN
Technical Notes:
phi:- Idiosyncratic component of the spatial error term
psi:- Individual time-invariant component of the spatial error term
rho:- Spatial autoregressive parameter
lambda:- Spatial autocorrelation coefficient

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ISSN: 1471-2458

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