Is a differentiated care model needed for patients with TB? A cohort analysis of risk factors contributing to unfavourable outcomes among TB patients in two states in South India

Table 3 Multivariate logistic regression for treatment outcomes (death and unfavourable outcomes) that considered background characteristics and combined risk of DCM

Characteristics	Experienced death					Experienced unfavourable outcome^c
Characteristics	UOR	AOR	95% CI		p- value	UOR	AOR	95% CI		p- value
Name of the State
Telangana (Reference)	1.00	1.00				1.00	1.00
Karnataka	1.55	1.42	0.94	2.16	0.099	2.52	2.35	1.71	3.23	< 0.001
Sex
Female (Reference)	1.00	1.00				1.00	1.00
Male	1.53	0.97	0.64	1.48	0.883	2.28	1.63	1.20	2.21	0.002
Initial weight^a
Median value or above (Reference)	1.00	1.00				1.00	1.00
Below median value	2.45	2.08	1.38	3.14	< 0.001	2.38	1.98	1.50	2.61	< 0.001
Weight unknown	2.05	2.12	1.32	3.38	0.002	1.64	1.74	1.25	2.43	0.001
Religion
Muslims (Reference)	1.00	1.00				1.00	1.00
Hindus	1.09	0.97	0.64	1.48	0.888	1.26	1.09	0.81	1.46	0.573
Others	1.89	1.84	0.81	4.15	0.143	1.47	1.44	0.76	2.72	0.261
Education status
Above 10 Standard (Reference)	1.00	1.00				1.00	1.00
< 5 Standard	8.28	5.39	2.11	13.79	< 0.001	3.59	2.68	1.67	4.31	< 0.001
5–10 Standard	5.12	3.96	1.53	10.22	0.004	3.02	2.41	1.50	3.86	< 0.001
Marital Status
Single (Reference)	1.00	1.00				1.00	1.00
Married	2.01	1.06	0.60	1.87	0.839	1.30	0.88	0.63	1.24	0.472
Marriage dissolved	2.51	0.93	0.38	2.26	0.872	1.64	1.07	0.59	1.94	0.815
Not known	NE	NE	NE	NE	NE	2.12	2.67	0.57	12.44	0.211
Type of TB
Extra Pulmonary TB (Reference)	1.00	1.00				1.00	1.00
Pulmonary TB	1.68	1.00	0.99	0.60	1.632	0.98	1.31	0.92	1.86	0.138
Number of risk present^b
No risk (Reference)	1.00	1.00				1.00	1.00
Only one risk present	3.94	3.28	2.11	5.10	< 0.001	2.21	1.71	1.29	2.26	< 0.001
More than one risk present	5.40	4.19	2.47	7.11	< 0.001	3.28	2.21	1.56	3.12	< 0.001

Note: Included patients aged 18 years and above whose RANA was administered between July and September and also treatment outcome was declared. UOR – Unadjusted odds ratio. AOR – Adjusted odds ratio. CI – Confidence Interval
^aConsidered median value of 43 Kgs for males and of 38 Kgs for females
^bRisk include, aged 60 and above, previously treated patients, DR TB patients, using alcohol, living alone, HIV positive patient, Diabetes patient
^cUnfavourable outcome includes death, failure and LFU patients

ISSN: 1471-2458