| Variable | Reference/Comparison | HR | 95% CI | p-val |
|---|
| < 5 years old in household | No < 5 years old in household | 6.29 | (5.61–7.06) | < 0.001 |
| For each increase in household size | Each additional person | 1.31 | (1.26–1.36) | < 0.001 |
| IMD Quintile | IMDQ1 | | | |
| IMDQ2 | | 0.74 | (0.59–0.92) | 0.01 |
| IMDQ3 | | 0.70 | (0.54–0.90) | 0.01 |
| IMDQ4 | | 0.59 | (0.46–0.75) | < 0.001 |
| IMDQ5 | | 0.55 | (0.41–0.74) | < 0.001 |
| Gender | Female | 0.98 | (0.88–1.08) | 0.67 |
| Ethnicity | Asian ethnicity | | | |
| Black | | 0.99 | 0.76–1.28 | 0.91 |
| Mixed | | 1.04 | 0.74–1.44 | 0.84 |
| Other | | 1.03 | 0.70–1.50 | 0.89 |
| White | | 0.69 | 0.54–0.88 | < 0.001 |
| Urban Rural Classification | Town & City (suburban) | | | |
| Conurbation | | 0.80 | (0.52–1.23) | 0.31 |
| Rural | | 1.06 | (0.80–1.39) | 0.69 |
| NHS Region | London | | | |
| Midlands & East | | 0.43 | (0.33–0.57) | < 0.001 |
| North | | 0.64 | (0.52–0.80) | < 0.001 |
| South | | 0.53 | (0.40–0.70) | < 0.001 |
- Table 3 shows the results of the frailty model. We found that there is an increased hazard ratio of household incidence where there is a child under 5 years old in a household (HR = 6.29, 95%CI 5.61–7.06). There is a decreasing trend in hazard ratios for IMD quintiles from most deprived category to least deprived: 0.74 (95%CI 0.59–0.92) for the second more deprived quintile through to 0.55 (95%CI 0.41–0.74) for the least deprived quintile. Overall, male gender was associated with less AGE (HR 0.98, 95%CI 0.88–1.08). White ethnicity (HR 0.69, 95%CI 0.54–0.88) had a lower HR than Asian but there were no other statistically significant differences. Each additional member of a household increased the HR of household incidence (HR 1.31, 95%CI 1.26–1.36). Conurbations had less household incidence than city and town, but there were no differences in rural settings. London NHS Region had a greater hazard of AGE than other parts of the country
- HR hazard ratio, CI confidence interval, IMD index of multiple deprivation
