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Table 3 Results of the frailty model, showing the variables included, reference group and the hazard ratio (HR) of household incidence of acute gastroenteritis

From: Household presentation of acute gastroenteritis in a primary care sentinel network: retrospective database studies

VariableReference/ComparisonHR95% CIp-val
< 5 years old in householdNo < 5 years old in household6.29(5.61–7.06)< 0.001
For each increase in household sizeEach additional person1.31(1.26–1.36)< 0.001
IMD QuintileIMDQ1   
 IMDQ2 0.74(0.59–0.92)0.01
 IMDQ3 0.70(0.54–0.90)0.01
 IMDQ4 0.59(0.46–0.75)< 0.001
 IMDQ5 0.55(0.41–0.74)< 0.001
GenderFemale0.98(0.88–1.08)0.67
EthnicityAsian ethnicity   
Black 0.990.76–1.280.91
Mixed 1.040.74–1.440.84
Other 1.030.70–1.500.89
White 0.690.54–0.88< 0.001
Urban Rural ClassificationTown & City (suburban)   
 Conurbation 0.80(0.52–1.23)0.31
 Rural 1.06(0.80–1.39)0.69
NHS RegionLondon   
Midlands & East 0.43(0.33–0.57)< 0.001
 North 0.64(0.52–0.80)< 0.001
 South 0.53(0.40–0.70)< 0.001
  1. Table 3 shows the results of the frailty model. We found that there is an increased hazard ratio of household incidence where there is a child under 5 years old in a household (HR = 6.29, 95%CI 5.61–7.06). There is a decreasing trend in hazard ratios for IMD quintiles from most deprived category to least deprived: 0.74 (95%CI 0.59–0.92) for the second more deprived quintile through to 0.55 (95%CI 0.41–0.74) for the least deprived quintile. Overall, male gender was associated with less AGE (HR 0.98, 95%CI 0.88–1.08). White ethnicity (HR 0.69, 95%CI 0.54–0.88) had a lower HR than Asian but there were no other statistically significant differences. Each additional member of a household increased the HR of household incidence (HR 1.31, 95%CI 1.26–1.36). Conurbations had less household incidence than city and town, but there were no differences in rural settings. London NHS Region had a greater hazard of AGE than other parts of the country
  2. HR hazard ratio, CI confidence interval, IMD index of multiple deprivation