Household presentation of acute gastroenteritis in a primary care sentinel network: retrospective database studies

Table 3 Results of the frailty model, showing the variables included, reference group and the hazard ratio (HR) of household incidence of acute gastroenteritis

Variable	Reference/Comparison	HR	95% CI	p-val
< 5 years old in household	No < 5 years old in household	6.29	(5.61–7.06)	< 0.001
For each increase in household size	Each additional person	1.31	(1.26–1.36)	< 0.001
IMD Quintile	IMDQ1
IMDQ2		0.74	(0.59–0.92)	0.01
IMDQ3		0.70	(0.54–0.90)	0.01
IMDQ4		0.59	(0.46–0.75)	< 0.001
IMDQ5		0.55	(0.41–0.74)	< 0.001
Gender	Female	0.98	(0.88–1.08)	0.67
Ethnicity	Asian ethnicity
Black		0.99	0.76–1.28	0.91
Mixed		1.04	0.74–1.44	0.84
Other		1.03	0.70–1.50	0.89
White		0.69	0.54–0.88	< 0.001
Urban Rural Classification	Town & City (suburban)
Conurbation		0.80	(0.52–1.23)	0.31
Rural		1.06	(0.80–1.39)	0.69
NHS Region	London
Midlands & East		0.43	(0.33–0.57)	< 0.001
North		0.64	(0.52–0.80)	< 0.001
South		0.53	(0.40–0.70)	< 0.001

Table 3 shows the results of the frailty model. We found that there is an increased hazard ratio of household incidence where there is a child under 5 years old in a household (HR = 6.29, 95%CI 5.61–7.06). There is a decreasing trend in hazard ratios for IMD quintiles from most deprived category to least deprived: 0.74 (95%CI 0.59–0.92) for the second more deprived quintile through to 0.55 (95%CI 0.41–0.74) for the least deprived quintile. Overall, male gender was associated with less AGE (HR 0.98, 95%CI 0.88–1.08). White ethnicity (HR 0.69, 95%CI 0.54–0.88) had a lower HR than Asian but there were no other statistically significant differences. Each additional member of a household increased the HR of household incidence (HR 1.31, 95%CI 1.26–1.36). Conurbations had less household incidence than city and town, but there were no differences in rural settings. London NHS Region had a greater hazard of AGE than other parts of the country
HR hazard ratio, CI confidence interval, IMD index of multiple deprivation

ISSN: 1471-2458