Table 2 Diagnostic Accuracy of the Neurobehavioral Screening Tool
Study | Study Information | Criteria for Positive Screen | Sensitivity (SD)a | Specificity (SD) a |
|---|---|---|---|---|
1. LaFrance et al., 2014 [30] | Sample Size = 80 Positives Included = 48 Positive Cases = Children with FASD diagnosis. Controls = Typically developing children. Average Age = 12 | ≥ 6 of items 1–7 or ≥ 3 of items 1–4. | 63% (6.9%) | 100% b (1.7%) |
2. Breiner et al., 2013 [31] | Sample Size = 60 Positives Included = 17 Positive Cases = Children with FASD diagnosis. Controls = 18 children suspected for FASD but for whom diagnosis could not be confirmed and 25 typically developing children. Median Age = 5 c | ≥ 5 of items 1, 2, 4–8. | 94% (5.6%) | 96% (3.0%) |
3. Nash et al., 2011 [32] | Sample Size = 109 Positives Included = 56 Positive Cases = Children with FASD diagnosis. Controls = Typically developing children. Average Age = 10 Sample Size = 106 | ≥ 3 of items 1–10 | 98% (1.9%) | 42% (6.7%) |
Positives Included = 56 Positive Cases = Children with FASD diagnosis. Controls = Children with ADHD diagnosis. Average Age = 10 | ≥ 2 of items 1, 4, 8, 9, 10. | 89% (4.1%) | 42% (6.9%) | |
4. Nash et al., 2006 [33] | Sample Size = 60 Positives Included = 30 Positive Cases = Children with FASD diagnosis. Controls = Typically developing children. Median Age = 11 c | ≥ 6 of items 1–7 | 86% (6.2%) | 82% (6.9%) |
Sample Size = 60 Positives Included = 30 Positive Cases = Children with FASD diagnosis. Controls = Children with ADHD diagnosis. Median Age = 11 c | ≥ 3 of items 1, 4, 8, 9, 10. | 81% (7.0%) | 72% (8.1%) |