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Table 2 Baseline and follow-up changes in physiological markers and disease risk predictions following 12-week intervention in participants who completed both the baseline and follow-up testing only

From: Evaluating differences in the clinical impact of a free online weight loss programme, a resource-intensive commercial weight loss programme and an active control condition: a parallel randomised controlled trial

  HWPNHSGYMΔ Change
Baseline ± SDFollow-up ± SDBaseline ± SDFollow-up ± SDBaseline ± SDFollow-up ± SDTimeTime x Intervention
AnthropometricsBody Mass (kg)106.38 ± 14.90101.21 ± 14.16103.13 ± 16.9298.94 ± 16.9798.98 ± 13.5497.81 ± 12.61< 0.001< 0.01
Body Mass Index (kg.m2)35.86 ± 3.4134.16 ± 3.7335.25 ± 3.5133.82 ± 3.8634.85 ± 2.9734.50 ± 3.20< 0.01< 0.05
Waist Circumference (cm)108.6 ± 12.3101.9 ± 8.8107.2 ± 12.096.4 ± 12.2104.9 ± 10.298.2 ± 11.3< 0.001NS
Hip Circumference (cm)119.5 ± 10.2114.6 ± 9.9119.0 ± 10.3113.7 ± 11.0117.8 ± 6.2115.0 ± 7.5< 0.001NS
Body Fat (%)40.9 ± 9.139.4 ± 8.939.4 ± 8.939.2 ± 7.540.3 ± 7.740.2 ± 7.9NSNS
Body Fat (kg)43.1 ± 9.339.4 ± 10.040.5 ± 11.138.7 ± 9.939.8 ± 9.039.2 ± 9.3NSNS
Fat Free Mass (kg)63.3 ± 15.160.5 ± 12.862.1 ± 14.660.4 ± 13.559.4 ± 12.358.2 ± 10.9< 0.01NS
HemodynamicsSystolic Blood Pressure (mmHg)138 ± 19134 ± 14129 ± 12129 ± 11129 ± 11130 ± 8NSNS
Diastolic Blood Pressure (mmHg)91 ± 1287 ± 882 ± 782 ± 881 ± 782 ± 7NSNS
Mean Arterial Pressure (mmHg)106 ± 14104 ± 1098 ± 899 ± 997 ± 797 ± 11NSNS
Resting Heart Rate (beat/min)70 ± 1070 ± 970 ± 1168 ± 968 ± 865 ± 9NSNS
HematologyFasting Blood Glucose (mmol/L)5.27 ± 0.665.20 ± 1.095.20 ± 0.514.76 ± 0.595.08 ± 0.504.90 ± 0.39< 0.05NS
Insulin (mlU/L)16 ± 2410 ± 610 ± 68 ± 420 ± 479 ± 5NSNS
HOMA-Insulin Resistance (au)3.8 ± 5.22.3 ± 1.22.4 ± 1.61.8 ± 1.05.0 ± 11.64.7 ± 11.6NSNS
Triglycerides (mmol/L)2.14 ± 1.491.68 ± 0.991.84 ± 1.221.4 ± 0.81.47 ± 0.871.40 ± 1.050.01NS
Total Cholesterol (mmol/L)5.29 ± 0.844.89 ± 1.035.43 ± 0.805.13 ± 0.745.00 ± 1.075.07 ± 1.46NSNS
HDL-Cholesterol (mmol/L)1.28 ± 0.301.31 ± 0.281.39 ± 0.401.49 ± 0.421.31 ± 0.361.38 ± 0.33< 0.001NS
Total: HDL Cholesterol Ratio4.4 ± 1.53.9 ± 1.24.3 ± 1.63.8 ± 1.34.0 ± 1.34.0 ± 2.1< 0.05NS
LDL-Cholesterol (mmol/L)3.31 ± 1.032.92 ± 0.953.26 ± 0.683.07 ± 0.773.08 ± 1.123.00 ± 1.02< 0.01NS
HbA1C DCCT (%)5.4 ± 0.75.2 ± 0.45.2 ± 0.45.1 ± 0.25.1 ± 0.35.1 ± 0.3< 0.05NS
Hba1C IFCC (mmol/mol)36 ± 733 ± 433 ± 432 ± 232 ± 433 ± 4< 0.05NS
Disease RiskQRISK2 Prediction (%)2.8 ± 2.02.3 ± 1.71.5 ± 1.51.3 ± 1.41.3 ± 1.11.3 ± 1.10.001NS
QDiabetes Risk Prediction (%)8.4 ± 5.37.2 ± 4.75.6 ± 5.16.6 ± 11.25.0 ± 4.14.6 ± 3.9NSNS
  1. Bold denotes significant main effect of time. Δ Change (p-Value) refers to difference between pre and post intervention for all groups (time). N = 18, 21 and 24 for HWP, NHS and GYM respectively. NS denotes Non-significant. Significance accepted as p < 0.05