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Table 1 Characteristic of the study subjects

From: First-degree family history of diabetes and its relationship with serum osteocalcin levels independent of liver fat content in a non-diabetic Chinese cohort

Variables

Total (n = 1206)

Non-FDR (n = 957)

FDR (n = 249)

Age (years)

59.7 (54.8–64.3)

59.9 (54.8–64.4)

59.0 (54.0–63.2)

Men, n (%)

413 (34.2)

337 (35.2)

76 (30.5)

BMI (kg/m2)

24.0 ± 3.2

24.0 ± 3.2

24.2 ± 3.3

W (cm)

82.0 (77.0–89.0)

82.0 (77.0–88.0)

83.0 (77.0–89.8)

SBP (mmHg)

129.0 (118.0–141.0)

130.0 (119.0–142.0)

124.0 (114.0–137.0) **

DBP (mmHg)

77.0 (70.0–84.0)

77.0 (71.0–85.0)

75.0 (68.0–82.0) **

FPG (mmol/L)

5.7 ± 0.5

5.7 ± 0.5

5.7 ± 0.5

2hPG (mmol/L)

7.0 ± 1.8

7.0 ± 1.7

7.2 ± 1.8*

HbA1c (%)

5.6 (5.4–5.9)

5.6 (5.4–5.8)

5.7 (5.5–5.9) **

HOMA-IR

2.2 (1.5–3.2)

2.2 (1.5–3.1)

2.2 (1.5–3.3)

TC (mmol/L)

5.4 (4.8–6.0)

5.4 (4.8–6.0)

5.3 (4.8–6.1)

TG (mmol/L)

1.4 (1.0–1.9)

1.4 (1.0–1.9)

1.4 (1.1–2.0)

HDL-C (mmol/L)

1.4 (1.2–1.7)

1.4 (1.2–1.7)

1.4 (1.2–1.7)

LDL-C (mmol/L)

3.3 (2.8–3.8)

3.3 (2.8–3.8)

3.3 (2.8–3.9)

CRP (mg/L)

0.9 (0.4–1.6)

0.9 (0.4–1.6)

0.9 (0.5–1.7)

ALT (U/L)

18.0 (14.0–24.0)

18.0 (14.0–24.0)

18.0 (14.0–24.0)

AST (U/L)

20.0 (18.0–24.0)

20.0 (18.0–24.0)

20.0 (17.5–24.0)

GGT (U/L)

22.0 (17.0–31.0)

22.0 (17.0–32.0)

22.0 (16.0–30.0)

LFC (%)

8.2 (6.6–22.2)

8.2 (6.6–22.6)

8.4 (6.6–16.2)

NAFLD, n (%)

479 (39.7)

379 (39.6)

100 (40.2)

Impaired glucose regulation, n (%)

513 (42.5)

392 (41.0)

121 (48.6) *

  1. Continuous variables are expressed as means ± standard deviation or medians with interquartile range. Categorical variables are expressed as numbers with percentages
  2. FDR versus non-FDR, *P < 0.05, **P < 0.01
  3. FDR first degree relatives of patients with diabetes, BMI body mass index, W waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, 2hPG 2-h plasma glucose, HbA1c glycated hemoglobin A1c, HOMA-IR homeostasis model assessment-insulin resistance index, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, CRP C-reactive protein, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transpeptidase, NAFLD non-alcoholic fatty liver disease