Age, maturation and serum lipid parameters: findings from the German Health Survey for Children and Adolescents

Schienkiewitz, Anja; Truthmann, Julia; Ernert, Andrea; Wiegand, Susanna; Schwab, Karl Otfried; Scheidt-Nave, Christa

doi:10.1186/s12889-019-7901-z

BMC Public Health

Table 4 Linear Regression of serum cholesterol parameters on pubertal stage among boys adjusted for age and behavioral determinants (n = 6531)

From: Age, maturation and serum lipid parameters: findings from the German Health Survey for Children and Adolescents

		TC [mg/dL]	HDL-C [mg/dL]	Non-HDL-C [mg/dL]
Model 1: unadjusted	R²	0.04	0.04	0.01
Early/mid-puberty	β (S.E.)	2.7 (1.2) ^*	3.0 (0.5) ^***	−0.3 (1.1)
Mature/advanced puberty	β (S.E.)	−10.8 (0.9) ^***	−4.5 (0.4) ^***	−6.3 (0.9) ^***
Model 2: adj. For age	R²	0.05	0.11	0.01
Early/mid-puberty	β (S.E.)	−4.3 (1.4) ^*	−1.9 (0.7) ^*	−2.4 (1.4)
Mature/advanced puberty	β (S.E.)	−18.7 (1.8) ^***	−6.8 (1.0) ^***	−11.8 (1.8) ^***
Age	β (S.E.)	0.2 (0.3)	−0.9 (0.2)^***	1.2 (0.4)^*
Age (squared)	β (S.E.)	−0.1 (0.0)^*	− 0.1 (0.0)^***	0.1 (0.0)^*
Model 3: adj. For age, BMI	R²	0.06	0.16	0.05
Early/mid-puberty	β (S.E.)	−4.5 (1.4) ^*	−1.6 (0.7) ^*	−2.9 (1.4) ^*
Mature/advanced puberty	β (S.E.)	−19.5 (1.8) ^***	−5.9 (1.0) ^***	−13.6 (1.7) ^***
Age	β (S.E.)	0.3 (0.3)	−1.1 (0.2)^***	1.4 (0.3)^***
Age (squared)	β (S.E.)	−0.1 (0.0)^*	− 0.2 (0.0)^***	0.1 (0.0)^*
BMI	β (S.E.)	2.5 (0.4)^***	−2.9 (0.2)^***	5.4 (0.4)^***
Model 4: adj. For age, BMI and behavioral determinants	R²	0.06	0.16	0.05
Early/mid-puberty	β (S.E.)	−4.4 (1.4)^*	−1.6 (0.7) ^*	−2.8 (1.4)
Mature/advanced puberty	β (S.E.)	−19.4 (1.8) ^***	−5.9 (1.0) ^***	−13.6 (1.8) ^***
Age	β (S.E.)	0.2 (0.4)	−1.1 (0.2)^***	1.2 (0.4)^*
Age (squared)	β (S.E.)	−0.1 (0.0)^*	−0.2 (0.0)^***	0.1 (0.0)^*
BMI	β (S.E.)	2.4 (0.4)^***	−2.9 (0.2)^***	5.3 (0.4)^***
Smoking (yes vs. no)	β (S.E.)	1.5 (1.6)	−0.8 (0.6)	2.3 (1.6)
Healthy food diversity index	β (S.E.)	1.4 (2.5)	−0.6 (1.2)	2.0 (2.6)
Low physical activity	β (S.E.)	1.0 (1.0)	−0.5 (0.4)	1.5 (0.9)
Middle physical activity	β (S.E.)	0.3 (1.0)	−0.4 (0.4)	0.7 (0.9)

Model 2: adjusted for age (centred and squared)
Model 3: adjusted for age (centred and squared) and BMI (kg/m², z-score)
Model 4: adjusted for age (centred and squared), BMI (kg/m², z-score), smoking, healthy food diversity index and physical activity
β Regression coefficient, S.E. Standard error, R² proportion of variance explained by the model, Reference = prepubescent stage
^*p < 0.05, ^**p < 0.001, ^***p < 0.0001

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