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Table 1 Summary information about the source materials used

From: Systematic review on HIV situation in Addis Ababa, Ethiopia

No.

Documents

Type of document

Key findings

Objectives

1

EPHI, 2018a

Report

ā€¢ HIV prevalence Table 2 and Figure 1

1

2

CSA and ICF, 2016

Survey

ā€¢ HIV prevalence 3.4% in Addis Ababa

ā€¢ Men who had sex with non-cohabiting partners is highest in Addis Ababa (26%) than the national average (16%)

ā€¢ The mean number of lifetime sexual partners reported by men in Addis Ababa (5.2%)

ā€¢ Women reported using a condom during last sexual intercourse with non-regular partners 41.8% and men 72.4%

ā€¢ Discordant couples (4.3%)

1, 3

3

EPHI, 2018b

Survey

ā€¢ HIV prevalence is 3.1% in Addis Ababa

ā€¢ VLS of whole country in urban areas is 70.1% (Female 71.7% and Male 66.8%), varies by age, sex, and region,

ā€¢ Status of the three 90ā€™s in Addis Ababa: 65.2 % for the 1st 90, 63.3 % for the 2nd 90 and 58.2% of all PLHIV

1, 5

4

Moher et al., 2015

Article

ā€¢ PRISMA Statement

-

5

CSA and ORC, 2005

Survey

ā€¢ HIV prevalence is 4.7% in Addis Ababa

1, 3

6

CSA and ICF, 2011

Survey

ā€¢ HIV prevalence is 5.2% in Addis Ababa

1, 3

7

EPHI, 2015

Report

ā€¢ Figure 1 for HIV prevalence

1

8

EPHI, 2011

Report

ā€¢ Figure 1 for HIV prevalence

1

9

EPHI, 2014

Report

ā€¢ Figure 1 for HIV prevalence

1

10

EPHI, 2017

Report

ā€¢ Figure 1 for HIV prevalence

1

11

FHAPCO, 2018

Report

ā€¢ Behavioural, biomedical and structural interventions

ā€¢ ART coverage is 74.6%; viral load testing coverage ~60% with 87.5% VLS

ā€¢ In Addis Ababa, the total number on ART were 94,240 and 3,616 were newly enrolled; retention at 12 months 87%

ā€¢ Figures 2, 3, 4

1, 5

12

EPHA/CDC (2012)

Report

ā€¢ Death related to HIV/AIDS in Figure 5

1

13

AAHAPCO, 2017

Synthesis

ā€¢ Key drivers of the epidemic; hotspot areas; intervention strategies; challenges on intervention

2, 3, 4, 5

14

Lakew et.al., 2015

Article

ā€¢ 5.7% HIV-positives among mobile workers

1, 4

15

FMOE, 2012

Survey

ā€¢ low level of knowledge, peer pressure, practices of unsafe sex, the proliferation of addictions (shisha, khat, alcohol) and substance abuse, genderā€“based violence were driving forces for the spread of the epidemic.

3, 4, 5

16

PSI/E, __

Research brief

ā€¢ Non-self-identified (NSI) FSWs to supplement their income to support family or the desire for fashion and luxury goods

ā€¢ The main barrier to condom use is higher payment, in addition to intimacy and trust with long-term clients

ā€¢ NSI FSWs felt some polices favor clients and they would be unlikely to get a positive outcome by reporting violence

ā€¢ NSI FSWs may be more likely to experience violence, but less likely to report it given the hidden nature of their work

3

17

Deyessa et al., 2018

Survey

ā€¢ Male users dominated female users at a ratio of 9:1; 3/4 of the IDUs were below the age of 35 years

ā€¢ The estimated IDUs in Addis Ababa were 4,068

ā€¢ The majority, 200 (72.5%) of the drug users from Addis Ababa had the habit of reusing needle and syringe

ā€¢ Of the 177 Addis Ababa residents who claimed to have tested for HIV, 70 (39.5%) disclosed as HIV positive

1, 3 ,4

18

Cherie et al., 2012

Article

ā€¢ Peer pressure is the most important factor associated with risky sexual behavior among school adolescents

3

19

Mirkuzie (2018)

Article

ā€¢ 2% and 4% of the HIV exposed babies were HIV positive by 6 and 18 months, respectively

ā€¢ No prophylactic ART and mixed feeding were predictors for having an HIV positive antibody test at 18 months

5

20

Klaus et al., 2015

Article

ā€¢ The barriers to PMTCT completion: hopelessness and carelessness, lack of understanding of the efficacy of ARV, and negative religious influences.

3

21

Endalamaw et al., 2018

Article

ā€¢ Rural residence, home delivery, no ART prophylaxis and mixed feeding increased the risk of HIV transmission

3

22

Menna et al., 2014

Article

ā€¢ High knowledge of HIV/AIDS, attitude towards ā€˜ABCā€™ rules, being tested for HIV and chewing khat are factors associated with multiple sexual partnerships among secondary school students.

3

23

EPHA et al., 2013

Report

ā€¢ The estimated HIV prevalence among FSWs in towns was 23.0%,; 4.5% in truck drivers

ā€¢ ~15.5% of drivers have misconceptions about HIV prevention methods

ā€¢ 21 % of drivers accept that once they had unprotected sex with someone, there is no reason to use condoms

ā€¢ Divorced/Separated/Widowed have also high HIV prevalence

1, 3, 4

24

UNODC, 2014

Survey

ā€¢ HIV prevalence 4.2% in prison settings

1, 4

25

PEPFAR, 2018

Strategic Plan

ā€¢ There are about 200,000 FSWs in Ethiopia

1, 4

26

PSI/E, 2016

Research brief

ā€¢ The majority of FSWs (57.5 %) are 24 years and younger, and about 14% are 19 years or younger

ā€¢ > 6% of HIV positive FSWs who started ART reported discontinuation of treatment for more than seven days in the three months prior to the assessment

1, 4, 5

27

Demissie et al., 2018

Article

ā€¢ The prevalence of HIV among IDUs was 6%

ā€¢ 40% of IDUs reported ever sharing needles; 56% reported sharing other injecting equipment; among HIV-positive IDUs, 60% reported sharing a needle the last time they injected.

ā€¢ Most of the IDUs were males (96%) with a mean age of 26 years.

1, 3, 4

28

FHAPCO, 2018

National roadmap

ā€¢ Key and priority populations

4

29

FMoH, 2018

Report

ā€¢ Behavioural, biomedical and structural interventions

5

30

Biadgilign et al., 2011

Article

ā€¢ Parents refusing to give consent for their children to access HIV testing services (HTS) and ART services

5

31

Gesesew et al., 2016

Article

ā€¢ Males being away from home, drug addiction, fear of stigma & discrimination, distance from ART clinics, dependent on food supplies, mental problems, HIV negative partners; and baseline CD4 <200 cells/mm3 and WHO clinical stages 3 & 4 were factors of ART discontinuation.

5

32

Gesesew et al., 2017a

Article

ā€¢ Being rural dweller, illiteracy, marriage, alcohol use, smoking, having mental illness and being bed ridden functional status, having HIV positive partner and being co-infected with TB/HIV were factors for ART discontinuation.

5

33

Gesesew et al., 2017b

Article

ā€¢ ART discontinued adults were more likely to be females, tuberculosis/HIV co-infected, with immunological failure and no history of HIV testing.

5

34

Bezabhe et al., 2014

Article

ā€¢ Economic constraints, perceived stigma & discrimination, medication side effects, and dissatisfaction with healthcare services, disclosure of HIV status, social support, responsibility for raising children, improved health on ART, and receiving education and counseling were factors for patients being non-adherent and lost to follow-up

5

35

Tiruneh and Wilson, 2016

Article

ā€¢ With the introduction of appointment spacing, some patients complain of lack of storage space for the six-month supply of ARTs, poor storage conditions for their medicines, and preference of frequent follow up. Health workers are also concerned about adherence given the less frequent contact of PLHIV with the health services

5

36

PEPFAR, 2016

Operation plan

ā€¢ Key and priority populations

4

37

FHAPCO, 2014

Strategic plan

ā€¢ HIV transmission interventions include behavioural, biomedical and structural components.

ā€¢ The plan intends to achieve the three 90 targets by 2020 through targeted social mobilization and HIV testing, linkage to care, quality of HIV treatment, and virtual elimination of MTCT, envisioning ending AIDS by 2030

5

38

Gudina et al., 2017

Article

ā€¢ Combination ART acheives sustained HIV viral suppression and contributes to improvement in the quality of life; and reductions in mortality, progression to AIDS, opportunistic infections (OIs), hospitalization, and decreased HIV transmission to uninfected persons

5

39

Misgena, 2011

Article

ā€¢ Challenges related to HAART include lifelong therapy, failed treatment response, optimal time to start treatment and switching regimens, drug interaction, toxicity, cardiovascular risks, drug resistance, lost to follow-up, immune reconstitution inflammatory syndrome (IRIS), early mortality, challenges in viral load testing.

5

40

Bernabas et al., 2017

Article

ā€¢ Noncompliance to medical instruction and poor adherence fosters emergence of drug resistance. Limited availability of laboratory services such as HIV RNA load and drug resistance testing and monitoring due to lack of experience of health professionals, and weak infrastructure and health care system contribute to delay in diagnosis of treatment failure

5

41

Telele et al., 2018

Article

ā€¢ The high rate of transmitted and preexisting drug resistance mutations in Ethiopian patients are identified

5

  1. Note: Objective representation of the agreed thematic areas, 1 = Determine the prevalence and incidence of HIV and mortality rate in the City; 2 = Identify the hot spot areas in the City; 3 = Establish factors involved in driving the epidemic in the city, through analysis of behavioural, biological, socio-economic and demographic data; 4 = Identify most-at-risk and priority population groups in the City Administration (sex workers, in-school youth, prisoners/inmates, discordant couples and IDUs); 5 = Quickly assess service availability, access and utilization for the identified most at risk/priority populations groups in the City Administration