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Table 3 RECAMP-MV - potential effect modifiers

From: Research protocol of two concurrent cluster-randomized trials: Real-life Effect of a CAMPaign with Measles Vaccination (RECAMP-MV) and Real-life Effect of a CAMPaign with Oral Polio Vaccination (RECAMP-OPV) on mortality and morbidity among children in rural Guinea-Bissau

Effect modifiersRationale
Prior MV statusPrior MV administration may lead to a larger reduction in non-accidental mortality/non-accidental morbidity than no prior MV administration [13, 14, 39, 40]
SexGirls may experience a larger reduction in non-accidental mortality/non-accidental morbidity than boys [40,41,42,43]
SeasonEnrolment in the dry season may lead to a larger reduction in non-accidental mortality/non-accidental morbidity than enrolment in the rainy season [29, 44]
Campaigns with other health interventionsVitamin A may amplify a beneficial non-specific effect [45]. Inactivated meningitis A and inactivated polio vaccination [42], and oral polio vaccination [17, 46], may neutralize/invert a between cluster difference. Participation status will be assigned on an ecological level, assuming that children eligible for campaigns with other health interventions receive these interventions on the campaign dates.