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Table 3 Predictors of suppressed viral load (< 50 copies/mL) at 12-month post-down-referral/ eligibility

From: Effective public-private partnerships for sustainable antiretroviral therapy: outcomes of the Right to Care health services GP down-referral program

 Suppressed VL (1535/2881)RRaRR
n (%)(95% CI)(95% CI)
Study cohort
 GP down-referred228 (65.7)11
 Clinic A controls934 (49.1)0.7 (0.7–0.8)1.0 (0.9–1.1)
 Clinic B controls373 (58.9)0.9 (0.8–0.99)1.0 (0.9–1.2)
Sex
 Female1036 (53.7)11
 Male499 (52.5)1.0 (0.9–1.1)1.0 (0.9–1.0)
Age at down-referral/eligibility (years) Median (IQR)
 18–29.99193 (55.3)11
 30–39.99657 (55.8)1.0 (0.9–1.1)1.0 (0.9–1.1)
 40–49.99481 (51.4)0.9 (0.8–1.0)0.9 (0.9–1.0)
 50+204 (48.8)0.9 (0.8–1.0)1.0 (0.9–1.1)
Nationality
 South African1363 (53.2)1 
 Non-South African172 (53.9)1.0 (0.9–1.1) 
Education level
 Primary school or less275 (51.7)1.0 (0.9–1.0) 
 Some secondary school350 (53.9)1.0 (0.9–1.1) 
  > =Grade 12765 (54.2)1 
Employment status
 Employed768 (53.6)1 
 Unemployed731 (52.9)1.0 (0.9–1.1) 
Time on ART at down-referral/eligibility (years) Median (IQR)
 1–2 year860 (54.6)11
 3–4 years350 (51.8)0.9 (0.9–1.0)1.0 (0.9–1.1)
  > =5 years325 (51.7)0.9 (0.9–1.0)0.9 (0.9–1.0)
Guideline year of ART initiation
 2004–2010929 (52.2)1 
 2010–2014606 (54.9)1.1 (0.98–1.1) 
Baseline CD4 (cells/μl)
 250–349.9472 (54.5)1.0 (0.96–1.0) 
 350–499.9510 (53.6)1.0 (0.9–1.1) 
  > =500553 (52.0)  
Baseline Haemoglobin (g/dL)1.0 (0.97–1.0) 
Baseline VL (copies/mL)
  < 501431 (81.4)11
 50–14961 (10.9)0.1 (0.1–0.2)0.1 (0.1–0.2)
 150–29933 (8.1)0.1 (0.1–0.1)0.1 (0.1–0.1)
 300–39910 (6.5)0.1 (0.04–0.1)0.1 (0.04–0.1)
Baseline BMI (kg/m2)
 Normal715 (54.1)1 
 Overweight382 (52.4)1.0 (0.9–1.1) 
 Obese222 (52.6)1.0 (0.9–1.1) 
ART regimen
 TDF + 3TC/FTC + EFV/NVP595 (55.7)11
 AZT + 3TC + EFV/NVP100 (60.2)1.1 (0.9–1.2)1.0 (0.9–1.1)
 d4T + 3TC + EFV/NVP825 (51.0)0.9 (0.9–0.98)1.0 (0.9–1.0)
12 month Retention
 Alive and in care1121 (55.5)11
 LTFU117 (47.0)0.9 (0.8–0.99)0.8 (0.7–0.9)
 Deceased16 (55.2)1.0 (0.7–1.4)1.0 (0.8–1.2)
 Transferred out281 (51.6)0.9 (0.9–1.0)0.9 (0.9–1.0)
  1. RR, risk ratio; aRR, adjusted relative risk; 95% CI, 95% confidence interval