Skip to main content

Table 2 Test for Treatment Effect on Primary Outcome (i.e. 7-day point prevalence, biochemically verified) on abstinence rate

From: Combined nicotine patch with gum versus nicotine patch alone in smoking cessation in Hong Kong primary care clinics: a randomised controlled trial

Outcome Single NRT (n = 286) Combined NRT (n = 274) OR (95% CI) p-value AOR (95% CI) p-value
No. of Success Abstinence Ratea (%) Available No. No. of Success Abstinence Ratea (%) Available No.
4 weeks 80 28.0 286 98 35.8 274 1.43 (1.00, 2.05) 0.048a 1.38 (0.95, 2.00) 0.087
12 weeks 48 16.8 286 60 21.9 274 1.39 (0.91,2.13) 0.130 1.37 (0.89, 2.13) 0.153
26 weeks 32 11.2 286 46 16.8 274 1.60 (0.99, 2.62) 0.057 1.56 (0.95, 2.57) 0.080
52 weeks 41 14.3 286 55 20.1 274 1.50 (0.97, 2.35) 0.073 1.49 (0.95, 2.36) 0.086
GEE 201 17.6 1114 259 23.6 1096 1.43 (1.16, 1.76) < 0.001** 1.43 (1.15, 1.77) 0.001**
  1. aAbstinence rate refers to 7-day point prevalence, biochemically verified, abstinence rates
  2. ** refers to p value with statistical significance
  3. Notes: NRT Nicotine replacement therapy
  4. OR Odds ratio. At each visit, crude odds ratio (combined NRT vs. single NRT) and p-value was reported from logistic regression without adjustment; for repeated measures, adjusted odds ratio and p-value was reported from Generalized Estimating Equation (GEE) adjusted for time
  5. AOR Adjusted odds ratio. At each visit, adjusted odds ratio (combined NRT vs. single NRT) and p-value was reported from logistic regression with adjustment for age, sex, baseline CO and cluster; for repeated measures, adjusted odds ratio and p-value was reported from GEE adjusted for time, age, sex, baseline CO and cluster