Combined nicotine patch with gum versus nicotine patch alone in smoking cessation in Hong Kong primary care clinics: a randomised controlled trial

Table 2 Test for Treatment Effect on Primary Outcome (i.e. 7-day point prevalence, biochemically verified) on abstinence rate

Outcome	Single NRT (n = 286)			Combined NRT (n = 274)			OR (95% CI)	p-value	AOR (95% CI)	p-value
Outcome	No. of Success	Abstinence Rate^a (%)	Available No.	No. of Success	Abstinence Rate^a (%)	Available No.	OR (95% CI)	p-value	AOR (95% CI)	p-value
4 weeks	80	28.0	286	98	35.8	274	1.43 (1.00, 2.05)	0.048^a	1.38 (0.95, 2.00)	0.087
12 weeks	48	16.8	286	60	21.9	274	1.39 (0.91,2.13)	0.130	1.37 (0.89, 2.13)	0.153
26 weeks	32	11.2	286	46	16.8	274	1.60 (0.99, 2.62)	0.057	1.56 (0.95, 2.57)	0.080
52 weeks	41	14.3	286	55	20.1	274	1.50 (0.97, 2.35)	0.073	1.49 (0.95, 2.36)	0.086
GEE	201	17.6	1114	259	23.6	1096	1.43 (1.16, 1.76)	< 0.001**	1.43 (1.15, 1.77)	0.001**

^aAbstinence rate refers to 7-day point prevalence, biochemically verified, abstinence rates
** refers to p value with statistical significance
Notes: NRT Nicotine replacement therapy
OR Odds ratio. At each visit, crude odds ratio (combined NRT vs. single NRT) and p-value was reported from logistic regression without adjustment; for repeated measures, adjusted odds ratio and p-value was reported from Generalized Estimating Equation (GEE) adjusted for time
AOR Adjusted odds ratio. At each visit, adjusted odds ratio (combined NRT vs. single NRT) and p-value was reported from logistic regression with adjustment for age, sex, baseline CO and cluster; for repeated measures, adjusted odds ratio and p-value was reported from GEE adjusted for time, age, sex, baseline CO and cluster

ISSN: 1471-2458