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Table 1 Characteristics of persons with latent tuberculosis infection who initiated INH monotherapy and followed for twelve months

From: Timing of treatment interruption among latently infected tuberculosis cases treated with a nine-month course of daily isoniazid: findings from a time to event analysis

Predictors (N = 12,495) Sample
N (%)
Treatment Completed
N (%)
Loss to Follow
N (%)
Chose to Stop
N (%)
Adverse Reaction
N (%)
Died
N (%)
p-value
   6201 (49.6) 3120 (25.0) 2928 (23.4) 237 (1.9) 9 (0.1)  
Type of Patients
Pediatric
Recent Contact
Other Adults
3150 (25.2)
1619 (13.0)
7726 (61.8)
1639 (52.0)
901 (55.6)
3661 (47.4)
823 (26.1)
382 (23.6)
1915 (24.8)
635 (20.2)
310 (19.1)
1983 (25.7)
53 (1.7)
25 (1.5)
159 (2.1)
-
1 (0.1)
8 (0.1)
<.0001
Gender
Female
Male
Missing
6076 (48.6)
6417 (51.4)
2 (0.0)
3090 (50.9)
3111 (48.5)
-
1433 (23.6)
1685 (26.3)
2 (100.0)
1400 (23.0)
1528 (23.8)
-
150 (2.5)
87 (1.4)
3 (0.0)
6 (0.1)
<.0001
Ethnicity
Non-Hispanic
Hispanic
Unknown
6808 (54.5)
5513 (44.1)
174 (1.4)
3714 (54.5)
2394 (43.4)
93 (53.4)
1881 (27.6)
1189 (21.6)
50 (28.7)
1093 (16.0)
1807 (32.8)
28 (16.1)
114 (1.7)
120 (2.2)
3 (1.7)
6 (0.1)
3 (0.0)
-
<.0001
Race
White
Black
Asian
Other
4496 (36.0)
4261 (34.1)
932 (7.5)
2806 (22.5)
2027 (45.1)
2035 (47.8)
650 (69.7)
1489 (53.1)
1004 (45.1)
1328 (47.8)
194 (20.8)
594 (21.2)
1350 (30.0)
833 (19.5)
80 (8.6)
665 (23.7)
110 (2.4)
63 (1.5)
7 (0.7)
57 (2.0)
5 (0.1)
2 (0.0)
1 (0.1)
1 (0.0)
<.0001
Birth Origin
U.S.-born
Non-U.S.-born, ≤ 5 Years
Non-U.S.-born, >  5 Years
5097 (40.8)
6517 (52.2)
881 (7.0)
2780 (54.5)
2998 (46.0)
423 (48.0)
1325 (26.0)
1591 (24.4)
204 (23.2)
890 (17.5)
1802 (27.6)
236 (26.8)
96 (1.9)
124 (1.9)
17 (1.9)
6 (0.1)
2 (0.0)
1 (0.1)
<.0001
HIV Co-infected
No
Yes
12,275 (98.2)
220 (1.8)
6038 (49.2)
163 (74.1)
3087 (25.1)
33 (15.0)
2907 (23.7)
21 (9.5)
236 (1.9)
1 (0.4)
7 (0.1)
2 (0.9)
<.0001
Diabetic        
No
Yes
12,512 (98.2)
170 (1.3)
6099 (49.5)
102 (60.4)
3079 (25.0)
41 (24.3)
2906 (23.6)
22 (13.0)
234 (1.9)
3 (1.8)
8 (0.1)
1 (0.6)
0.0010
Other Immunosuppressive Conditions*
No
Yes
12,395 (99.2)
100 (0.8)
6136 (49.5)
65 (65.0)
3104 (25.0)
16 (16.0)
2913 (23.5)
15 (15.0)
235 (1.9)
2 (2.0)
7 (0.1)
2 (2.0)
<.0001
  1. Notes: * includes individuals with hematologic disorders (n = 6), chronic renal failure (n = 21), non-HIV related immunosuppressive conditions (n = 48), and those on corticosteroid therapy (n = 21)