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Table 1 Demographics, anthropometric parameters and clinical characteristics of virologically suppressed HIV-infected and un-infected control participants in the study

From: Prevalence and associated risk factors of peripheral artery disease in virologically suppressed HIV-infected individuals on antiretroviral therapy in Kwara state, Nigeria: a cross sectional study

Participants (n)

Study group (n = 150)

Control group (n = 50)

P-value

Age (yrs.)

43.73 ± 8.74

43.47 ± 8.87

0.714

Gender

 Male (%)

41 (27.3)

23 (46)

0.091

 Female (%)

109 (72.7)

27 (54)

0.084

Clinical characteristics

 ABI

0.92 ± 0.08

0.94 ± 0.05

0.175

 SBP (mmHg)

121 ± 21

116 ± 17

0.110

 DBP (mmHg)

81 ± 8

76 ± 6

0.001*

 BMI (kg/m2)

25.43 ± 5.46

25.67 ± 4.93

0.778

 BMI 18.5–24. kg/m2 (%)

78 (52)

26 (52)

0.380

 BMI 25–29.9 kg/m2 (%)

38 (25.3)

13 (26)

0.250

 BMI ≥ 30 kg/m2 (%)

34 (22.7)

11 (22)

0.350

 WC (cm)

90.13 ± 11.52

90.58 ± 11.13

0.808

 WHR

0.88 ± 0.048

0.88 ± 0.053

0.486

 Duration of HIV infection (yrs.)

7.73 ± 3.52

N/A

 

 Duration on ART (yrs.)

7.47 ± 3.42

N/A

 

 Nadir CD4+ T cell count (cells/mm3)

263 ± 230

N/A

 

 Current CD4+ T cell count (cells/mm3)

505 ± 266

N/A

 

 HIV viral RNA count (copies/ml)

40.95 ± 111.61

N/A

 

 Undetectable viremia (< 20 copies/ml)

104 (69.3)

  

 Detectable viremia (≥20 copies/ml)

46 (30.7)

N/A

 

ART Drug regime

 NRTI/NNRTI (AZT/3TC/NVP) (%)

93 (62.0)

N/A

 

 NRTI/NNRTI (TDF/3TC/EFV) (%)

46 (30.7)

N/A

 

 NRTI/Protease inhibitor (TDF/3TC/LPV/r) (%)

11 (7.3)

N/A

 
  1. Data are presented as mean ± standard deviation or numbers (percentages). * = significant at P < 0.05. PAD Peripheral artery disease, ABI Ankle brachial index, SBP Systolic blood pressure, DBP Diastolic blood pressure, BMI Body mass index, WC Waist circumference, WHR Waist to hip ratio, CVD Cardiovascular disease, NRTI Nucleoside reverse transcriptase inhibitor; NNRTI Non-nucleoside reverse transcriptase inhibitor, AZT/3TC/NVP Zidovudine/lamivudine/nevirapine, TDF/3TC/EFV Tenofovir/lamivudine/efavirenz, LPV/r Lopinavir/ritonavir, N/A Not applicable