Table 2 Baseline Laboratory and Clinical characteristics of Children commencing ART at LCH
Characteristic | < 1 year | 1–5 years | 6–15 years | Total |
|---|---|---|---|---|
N = 179 (17%) | N = 387 (37%) | N = 473 (46%) | N = 1039 | |
CD4 count at enrollment Median (IQR) | 1028 (535–1498) | 777 (444–1135) | 278 (118–487) | 505 (243–948) |
CD4 percent at enrollment Median (IQR) | 19.4 (12.4–25.6) | 16.7 (11.3–21.5) | 14.0 (8.3–21.2) | 16.2 (10–23) |
Hemoglobin at enrollment (Median IQR)) | 8.8 (7.8–9.7) | 9.3 (8.0–10.5) | 10.3 (9–11.5) | 9.6 (8.3–10.9) |
Taking Cotrimoxazole at enrollment | ||||
Yes | 169 (17%) | 378 (38%) | 451 (45%) | 1000 |
No | 9 (23%) | 8 (21%) | 22 (56%) | 39 |
Drug regimen at ART initiation N(%) | ||||
3 NRTI’s | 30 (38%) | 46 (59%) | 2 (3%) | 78 |
2NRTIs +1NNRTI | 130 (14%) | 320 (35%) | 457 (50%) | 907 |
LPV/r based | 19 (35%) | 21 (39%) | 14 (26%) | 54 |
Year of ART start N(%) | ||||
2003–2005 | 3 (4%) | 17 (24%) | 51 (72%) | 71 |
2006–2009 | 88 (17%) | 202 (39%) | 222 (43%) | 512 |
2010–2012 | 62 (20%) | 117 (38%) | 126 (41%) | 305 |
2013–2015 | 26 (17%) | 51 (34%) | 74 (49%) | 151 |
Mom took ARVs for PMTCT during pregnancy | ||||
Yes | 69 (45%) | 71 (46%) | 14 (9%) | 154 |
No | 110 (12%) | 316 (36%) | 459 (52%) | 885 |
Child took ARV prophylaxis after birth N(%) | ||||
Yes | 55 (43%) | 58 (47%) | 8 (10%) | 123 |
No | 124 (14%) | 329 (36%) | 463 (51%) | 810 |
Nutritional status at enrollment | ||||
Weight for height score < −3SD | 36 (20%) | 88 (48%) | 58 (32%) | 182 |
weight for height score > −3 SD | 143 (17%) | 299 (35%) | 415 (48%) | 857 |
Baseline clinical staging (WHO stage) N(%) | ||||
WHO stage 1 | 52 (24%) | 64 (29%) | 103 (47%) | 219 |
WHO stage 2 | 20 (13%) | 39 (25%) | 99 (63%) | 158 |
WHO stage 3 | 65 (14%) | 200 (43%) | 206 (44%) | 471 |
WHO stage 4 | 41 (23%) | 78 (44%) | 58 (33%) | 177 |
missing | 1 | 6 | 7 | 14 |
Diseases at baseline N(%) | ||||
TB | 33 (10%) | 105 (33%) | 178 (56%) | 318 |
pneumonia | 35 (21%) | 68 (41%) | 61 (27%) | 165 |
Diarrhea | 45 (18%) | 117 (47%) | 84 (34%) | 247 |
Gestation age at birth N(%) | ||||
Premature | 4 (25%) | 8 (50%) | 4 (25%) | 16 |
term | 107 (22%) | 201 (41%) | 175 (36%) | 485 |
unknown | 68 (13%) | 178 (33%) | 294 (54%) | 544 |
Mode of delivery N(%) | ||||
C/Section | 5 (28%) | 3 (17%) | 10 (56%) | 18 |
SVD | 105 (21%) | 206 (42%) | 180 (37%) | 491 |
unknown | 69 (13%) | 178 (34%) | 283 (53%) | 530 |