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Table 2 Data on self-reported symptom clusters in the sample (n = 1086)

From: Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain

Symptoms Employed (n = 450) Unemployed (n = 636) p-valuea
Muscular
 Generalized chronic pain 380 (84.4) 583 (91.7) <  0.001***
 Muscle weakness 439 (97.6) 619 (97.3) 0.815
 Post-exertional malaise 441 (98.0) 630 (99.1) 0.142
 Difficulty performing fine movements due to pain 389 (86.4) 553 (86.9) 0.809
 Marked muscle contractures 396 (88.0) 567 (89.2) 0.555
 Myoclonic 156 (34.7) 264 (41.6) 0.023*
 Falls due to loss of tone 74 (16.4) 159 (25.0) 0.001***
Cognitive
 Concentration impairments 424 (94.2) 616 (96.9) 0.034*
 Alterations in short-term memory consolidation 410 (91.1) 610 (95.9) 0.001***
 Alterations during task planning 355 (78.9) 577 (90.7) <  0.001***
 Difficulty with calculation 385 (85.6) 584 (91.8) 0.001***
 Difficulty redding 402 (89.3) 594 (93.4) 0.017*
 Confusion and forgetfulness 361 (80.2) 560 (88.1) <  0.001***
 Temporal-spatial disorientation 282 (62.7) 481 (75.6) <  0.001***
 Episodes of nominal aphasia 382 (84.9) 565 (88.8) 0.055
 Auditory and visual agnosia 133 (29.6) 257 (40.4) <  0.001***
Neurological
 Ataxia and/or dissymmetry 331 (73.6) 514 (80.8) 0.005**
 Sensory hypersensitivity 403 (89.6) 582 (91.5) 0.275
 Visual alterations 290 (64.4) 472 (74.2) 0.001***
 Motor incoordination, with or without falls 339 (75.3) 511 (80.3) 0.048*
Autonomic
 Dizziness or cephalic instability 356 (79.1) 552 (86.8) 0.001***
 Vertigo 322 (71.6) 496 (78.0) <  0.001***
 Orthostatic hypotension 342 (76.0) 512 (80.5) 0.009**
 Lipothymia 80 (17.8) 171 (26.9) 0.017*
 Syncope 48 (10.7) 98 (15.4) 0.015*
 Frequent palpitations 313 (69.6) 495 (77.8) 0.074
 Tremor 171 (38.0) 314 (49.4) <  0.001***
 Profuse sweating 285 (63.3) 451 (70.9) 0.024*
 Altered bowel habits 296 (65.8) 467 (73.4) 0.002**
 Alterations in urination 224 (49.8) 395 (62.1) <  0.001***
 Reduced libido/anorgasmia/impotence 314 (69.8) 489 (76.9) 0.008**
 Difficulties in visual accommodation 321 (71.3) 494 (77.7) 0.007**
Inmunological
 Recurrent low-fever 326 (72.4) 473 (74.4) 0.478
 Recurrent odynophagia 306 (68.0) 477 (75.0) 0.060
 Painful lymph nodes 236 (52.4) 389 (61.2) 0.061
 Raynaud’s phenomenon 125 (27.8) 225 (35.4) 0.552
 Generalized morning numbness 343 (76.2) 521 (81.9) 0.743
 Migratory arthralgias 376 (83.6) 547 (86.0) 0.996
 Allergy to multiple medications 95 (21.1) 168 (26.4) 0.011*
 Food intolerance 41 (9.1) 78 (12.3) 0.004**
 Allergy to multiple metals 51 (11.3) 110 (17.3) 0.008**
 History of sinusitis 30 (6.7) 63 (9.9) 0.022*
 Facial swelling 19 (4.2) 44 (6.9) 0.265
 Mouth ulcers 238 (52.9) 348 (54.7) 0.044*
 Herpes 226 (50.2) 313 (49.2) 0.101
 Candidiasis 172 (38.2) 243 (38.2) 0.006**
  1. Data are expressed as numbers of cases (percentages) among sample unless otherwise indicated
  2. *Significance at 0.05
  3. **Significance at 0.01
  4. ***Significance at 0.001
  5. a Data analysis was performed using Chi-square test for categorical variables