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Table 2 Data on self-reported symptom clusters in the sample (n = 1086)

From: Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain

Symptoms

Employed (n = 450)

Unemployed (n = 636)

p-valuea

Muscular

 Generalized chronic pain

380 (84.4)

583 (91.7)

<  0.001***

 Muscle weakness

439 (97.6)

619 (97.3)

0.815

 Post-exertional malaise

441 (98.0)

630 (99.1)

0.142

 Difficulty performing fine movements due to pain

389 (86.4)

553 (86.9)

0.809

 Marked muscle contractures

396 (88.0)

567 (89.2)

0.555

 Myoclonic

156 (34.7)

264 (41.6)

0.023*

 Falls due to loss of tone

74 (16.4)

159 (25.0)

0.001***

Cognitive

 Concentration impairments

424 (94.2)

616 (96.9)

0.034*

 Alterations in short-term memory consolidation

410 (91.1)

610 (95.9)

0.001***

 Alterations during task planning

355 (78.9)

577 (90.7)

<  0.001***

 Difficulty with calculation

385 (85.6)

584 (91.8)

0.001***

 Difficulty redding

402 (89.3)

594 (93.4)

0.017*

 Confusion and forgetfulness

361 (80.2)

560 (88.1)

<  0.001***

 Temporal-spatial disorientation

282 (62.7)

481 (75.6)

<  0.001***

 Episodes of nominal aphasia

382 (84.9)

565 (88.8)

0.055

 Auditory and visual agnosia

133 (29.6)

257 (40.4)

<  0.001***

Neurological

 Ataxia and/or dissymmetry

331 (73.6)

514 (80.8)

0.005**

 Sensory hypersensitivity

403 (89.6)

582 (91.5)

0.275

 Visual alterations

290 (64.4)

472 (74.2)

0.001***

 Motor incoordination, with or without falls

339 (75.3)

511 (80.3)

0.048*

Autonomic

 Dizziness or cephalic instability

356 (79.1)

552 (86.8)

0.001***

 Vertigo

322 (71.6)

496 (78.0)

<  0.001***

 Orthostatic hypotension

342 (76.0)

512 (80.5)

0.009**

 Lipothymia

80 (17.8)

171 (26.9)

0.017*

 Syncope

48 (10.7)

98 (15.4)

0.015*

 Frequent palpitations

313 (69.6)

495 (77.8)

0.074

 Tremor

171 (38.0)

314 (49.4)

<  0.001***

 Profuse sweating

285 (63.3)

451 (70.9)

0.024*

 Altered bowel habits

296 (65.8)

467 (73.4)

0.002**

 Alterations in urination

224 (49.8)

395 (62.1)

<  0.001***

 Reduced libido/anorgasmia/impotence

314 (69.8)

489 (76.9)

0.008**

 Difficulties in visual accommodation

321 (71.3)

494 (77.7)

0.007**

Inmunological

 Recurrent low-fever

326 (72.4)

473 (74.4)

0.478

 Recurrent odynophagia

306 (68.0)

477 (75.0)

0.060

 Painful lymph nodes

236 (52.4)

389 (61.2)

0.061

 Raynaud’s phenomenon

125 (27.8)

225 (35.4)

0.552

 Generalized morning numbness

343 (76.2)

521 (81.9)

0.743

 Migratory arthralgias

376 (83.6)

547 (86.0)

0.996

 Allergy to multiple medications

95 (21.1)

168 (26.4)

0.011*

 Food intolerance

41 (9.1)

78 (12.3)

0.004**

 Allergy to multiple metals

51 (11.3)

110 (17.3)

0.008**

 History of sinusitis

30 (6.7)

63 (9.9)

0.022*

 Facial swelling

19 (4.2)

44 (6.9)

0.265

 Mouth ulcers

238 (52.9)

348 (54.7)

0.044*

 Herpes

226 (50.2)

313 (49.2)

0.101

 Candidiasis

172 (38.2)

243 (38.2)

0.006**

  1. Data are expressed as numbers of cases (percentages) among sample unless otherwise indicated
  2. *Significance at 0.05
  3. **Significance at 0.01
  4. ***Significance at 0.001
  5. a Data analysis was performed using Chi-square test for categorical variables