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Table 2 Summary of health, exposure, and other participant and household measurements

From: Study protocol for a stepped-wedge randomized cookstove intervention in rural Honduras: household air pollution and cardiometabolic health

Measurement Description Source Groups Measured Timinga
Primary health endpoints Blood pressure (brachial systolic and diastolic) C-reactive protein (systemic inflammation) Glycated hemoglobin (HbA1c) SphygmoCor XCEL monitor Dried blood spots Finger-stick point-of-care instrument All participants All participants All participants All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2
Secondary health endpoints Other biomarkers of systemic injury and inflammation Metabolomics Augmentation index and central pulse pressure Blood lipids (LDL, HDL, total cholesterol, triglycerides) Self-reported health symptoms Fractional exhaled nitric oxide (airway inflammation) Telomere length from buccal cells Dried blood spots Dried blood spots SphygmoCor XCEL Finger-stick point-of-care instrument Questionnaires NIOX Vero and Aero monitors Buccal scrapes All participants All participants All participants All participants All participants Sub-set of participants Sub-set of participants All 6 visits, day 2 Visit 1 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 Visits 1-4, day 2
Exposure assessments Assigned stove type Randomization All participants See Table 1 scheme
Kitchen
 PM2.5  Black carbon  Ultrafine PM  Real time and gravimetric PM2.5  Carbon monoxide Triplex cyclone and AirChek pump PM2.5 Filters and Sootscan Discmini Personal Data Ram Dräger Pac 7000 All kitchens All kitchens Sub-set of kitchens Sub-set of kitchens All kitchens All 6 visits, 24-hours All 6 visits, 24-hours Visits 1-4, 24-hours Visits 1-4, 24-hours Visits 1-3, 24-hours
Personal
 PM2.5  Black carbon  Compliance with wearing monitors  Carbon monoxide Triplex cyclone and AirChek pump, UPAS PM2.5 Filters and Sootscan Accelerometer Dräger Pac 7000 All participants All participants All participants All participants All 6 visits, 24-hours All 6 visits, 24-hours All 6 visits, 24-hours Visits 1-3, 24-hours
Other sources of household air pollution Neighbors, traffic, trash burning, kerosene use Smoking status (cigarettes and puro) Secondhand smoke exposure Questionnaires Questionnaires Screening All participants All participants All participants All 6 visits, day 1 Screening and all 6 visits, day 2 Screening
Stove use Self-reported use of all cookstoves, behaviors Electronic monitoring of cookstove temperature Justa cookstove maintenance, changes, preferences Time cooking separately for animals Questionnaires Stove Use Monitors (SUMs) Questionnaires Questionnaires All participants All cookstoves Justa recipients All participants All 6 visits, day 2 All 6 visits, 24-hours Visits 3-6, day 2 All 6 visits, day 2
Household and kitchen characteristics Elevation and GPS coordinates Kitchen temperature and humidity Kitchen ventilation/openings Kitchen location, size, and housing materials Maps.me on smart phones EasyLog monitor Questionnaires Questionnaires All households All kitchens All kitchens All kitchens Visit 1 (repeated if new house) All 6 visits, 24-hours Visit 1 (repeated if new house) Visit 1 (repeated if new house)
Socioeconomic and demographics Income sources Material items, electricity, education, beds, age Household size, age of youngest child Questionnaires Questionnaires Questionnaires All participants All participants All participants All 6 visits, day 1 Visit 1, day 1 All 6 visits, day 1
Other health-related measures Illnesses, previous diagnoses Medication and vitamin use 24-hour dietary recall and diversity Weekly physical activity Body mass index (BMI), waist and hip circumference Pregnancy Questionnaires Questionnaires Questionnaires Questionnaires Anthropometric measures Screening and Questionnaires All participants All participants All participants All participants All participants All participants All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 All 6 visits, day 2 Screening and all 6 visits, day 1
  1. aWomen received six repeated measures over the 3-year study period, with approximately six months between visits. Each study visit included two consecutive days of data collection: day 1 set-up of all exposure monitors, and day 2 take-down of monitors and collection of health measures. Further details on timing and collection procedures can be found in the “Study visits” section