Table 1 AIDS-defining diseases among Israeli Men having sex with Men according to HIV treatment regimen period, Israel, 1981–2015
HIV treatment regimen period | 1981–1996 | 1997–2007 | 2008–2015 | 1981–2015 | ||||
|---|---|---|---|---|---|---|---|---|
Number of AIDS cases | N = 186 | N = 69 | N = 41 | N = 296 | ||||
Diseases | Diagnosis | %a | Diagnosis | %a | Diagnosis | %a | Diagnosis | %a |
Pneumocystis carinii pneumonia | 81 | 43.5 | 19 | 27.5 | 18 | 43.9 | 118 | 39.9 |
Kaposi’s sarcoma | 44 | 23.7 | 10 | 14.5 | 5 | 12.2 | 59 | 19.9 |
Wasting syndrome due to HIV | 32 | 17.2 | 16 | 23.2 | 1 | 2.4 | 49 | 16.6 |
Candidiasis, esophageal | 22 | 11.8 | 6 | 8.7 | 2 | 4.9 | 30 | 10.1 |
Toxoplasmosis of brain in a patient over one month of age | 22 | 11.8 | 4 | 5.8 | 1 | 2.4 | 27 | 9.1 |
Cytomegalovirus retinitis | 21 | 11.3 | 0 | 0.0 | 0 | 0.0 | 21 | 7.1 |
Cryptococcosis, extrapulmonary | 15 | 8.1 | 1 | 1.4 | 3 | 7.3 | 19 | 6.4 |
Opportunistic Infections, not specified | 9 | 4.8 | 6 | 8.7 | 4 | 9.8 | 19 | 6.4 |
Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary | 14 | 7.5 | 1 | 1.4 | 1 | 2.4 | 16 | 5.4 |
Pneumonia, recurrent in an adult or an adolescent (aged 13 years or over) | 11 | 5.9 | 2 | 2.9 | 2 | 4.9 | 15 | 5.1 |
Cytomegalovirus disease (other than liver, spleen or nodes) in a patient over one month of age | 9 | 4.8 | 3 | 4.3 | 2 | 4.9 | 14 | 4.7 |
Lymphoma, not specified | 9 | 4.8 | 3 | 4.3 | 1 | 2.4 | 13 | 4.4 |
Cryptosporidiosis, intestinal with diarrhea (> 1 month duration) | 9 | 4.8 | 2 | 2.9 | 0 | 0.0 | 11 | 3.7 |
Lymphoma, immunoblastic | 5 | 2.7 | 5 | 7.2 | 0 | 0.0 | 10 | 3.4 |
Lymphoma, Burkitt’s | 2 | 1.1 | 3 | 4.3 | 4 | 9.8 | 9 | 3.0 |
Herpes simplex: chronic ulcer(s) (> 1 month duration) or bronchitis, pneumitis or esophagitis in a patient over 1 month of age | 8 | 4.3 | 0 | 0.0 | 0 | 0.0 | 8 | 2.7 |
Lymphoma, primary, of the brain | 6 | 3.2 | 0 | 0.0 | 1 | 2.4 | 7 | 2.4 |
Encephalopathy, HIV-related | 5 | 2.7 | 1 | 1.4 | 1 | 2.4 | 7 | 2.4 |
Progressive multifocal leukoencephalopathy | 4 | 2.2 | 2 | 2.9 | 0 | 0.0 | 6 | 2.0 |
Mycobacterium tuberculosis, pulmonary in an adult or adolescent (aged 13 or over) | 0 | 0.0 | 4 | 5.8 | 2 | 4.9 | 6 | 2.0 |
Mycobacterium tuberculosis, pulmonary in an adult or adolescent | 1 | 0.5 | 2 | 2.9 | 1 | 2.4 | 4 | 1.4 |
Mycobacterium, other species or unidentified species, disseminated or extrapulmonary | 2 | 1.1 | 0 | 0.0 | 0 | 0.0 | 2 | 0.7 |
Salmonella (non-typhoid) septicaemia, recurrent | 0 | 0.0 | 2 | 2.9 | 0 | 0.0 | 2 | 0.7 |
Candidas of the bronchi, trachea or lungs | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 1 | 0.3 |
Histoplasmosis, disseminated or extrapulmonary | 1 | 0.5 | 0 | 0.0 | 0 | 0.0 | 1 | 0.3 |
Total number of diagnoses | 333 | 179.0 | 92 | 133.3 | 49 | 119.5 | 474 | 160.1 |