Prevalence, incidence, and risk factors of primary open-angle glaucoma - a cohort study based on longitudinal data from a German public health insurance

Table 7 Results of the Cox-regression model, risk of incidence of POAG, 2011–2013, AOK data

	Factors	Hazard Ratio	p-Value	95%-Confidence
Age	50–54	1
	55–59	1.25	0.045	(1.00–1.55)
	60–64	2.20	< 0.001	(1.80–2.69)
	65–69	2.49	< 0.001	(2.04–3.05)
	70–74	3.37	< 0.001	(2.80–4.06)
	75–79	3.67	< 0.001	(3.04–4.44)
	80–84	3.49	< 0.001	(2.85–4.26)
	85–89	3.44	< 0.001	(2.75–4.31)
	90+	2.39	< 0.001	(1.74–3.27)
Sex	Women (Ref. Men)	1.19	< 0.001	(1.09–1.30)
Morbidities (selection)	Ever degeneration of iris and ciliary body	2.55	0.22	(1.14–5.70)
	Ever myopia	2.55	<0.001	(2.29–2.84)
	Ever injury of eye and orbit	2.75	<0.001	(1.56–4.86)
	Ever retinal vascular occlusions	2.34	<0.001	(1.71–3.20)
	Ever diabetes mellitus	1.23	<0.001	(1.13–1.35)
	Ever hypertension	1.13	0.008	(1.03–1.24)
	Ever smoking related cancer	0.78	0.020	(0.63–0.96)

Note: Insignificant hazard ratios are not shown in the table, but the model is further adjusted for papilledema, hypotension, ischemic heart disease, migraine, sleep apnea, obstructive pulmonary disease, vasospasm and obesity

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