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Table 1 Semi-parametric generalized additive model (GAM) for psychosocial and behavioral outcomes among PLWH in France (ANRS-VESPA2 survey)

From: A generalized additive model to disentangle age and diagnosis-specific cohort effects in psychological and behavioral outcomes in people living with HIV: the French cross-sectional ANRS-VESPA2 survey

 

Physical QoL

Mental QoL

Need for material support

Need for moral support

HIV-status disclosure N = 3016

N = 2267

N = 3006

N = 3016

Parametric part of the model

 

Coeff. [95% CI]

Coeff. [95% CI]

Coeff. [95% CI]

Coeff. [95% CI]

Coeff. [95% CI]

 Intercept

50.6 [49.4;51.7]c

42.0 [41.0;43.1]c

0.0 [−0.2;0.2]

0.8 [0.6;1.1]c

2.3 [1.8;2.7]c

 Sex

  Male

ref

ref

ref

ref

ref

  Female

−1.3 [− 2.2;-0.5]b

− 1.0 [− 2.1;0.1]

0.4 [0.2;0.6]c

1.1 [0.8;1.4]c

0.6 [0.2;1.1]b

 MSM

  Yes

   

0.4 [0.2;0.7]c

0.5 [0.0;1.0]a

  No

   

ref

ref

 Immigrant from Sub-Saharan Africa

  Yes

−2.6 [−3.7;-1.5]c

5.0 [3.6;6.4]c

0.8 [0.5;1.1]c

 

−1.1 [−1.5;−0.6]c

  No

ref

ref

ref

 

ref

 Marital status

  Married or cohabitating

 

1.9 [1.0;2.9]c

-0.6 [−0.8;-0.4]c

 

1.4 [0.9;1.8]c

  Single, divorced or widowed

 

ref

ref

 

ref

 Children

  Yes

  

0.2 [0.0;0.4]a

  

  No

  

ref

  

 Professional status

  Employed

2.9 [2.1;3.6]c

2.1 [1.1;3.1]c

−0.5 [−0.7;-0.3]c

  

  Other (unemployed, inactive)

ref

ref

ref

  

 Education level

  < High school

ref

   

ref

  = High school

−0.4 [−1.5;0.6]

   

0.6 [0.2;1.0]b

  > High school

1.3 [0.1;2.4]a

   

0.5 [0.0;0.9]

 Perceived care-related discrimination (in the previous 2 years)

  Yes

−3.1 [− 4.3;-1.9]c

− 4.2 [− 5.7;2.6]c

0.5 [0.2;0.8]b

0.4 [0.0;0.8]a

 

  No

ref

ref

ref

ref

 

 Perceived financial situation

  Difficult

−2.5 [−3.3;-1.6]c

−4.9 [− 6.0;-3.8]c

1.7 [1.4;1.9]c

0.7 [0.5;1.0]c

 

  Adequate

ref

ref

ref

ref

 

  Comfortable

0.8 [−0.2;1.9]

1.7 [0.5;3.0]b

−1.1 [−1.3;-0.8]c

− 0.2 [− 0.5;0.0]a

 

 Beneficiary of free universal health coverage

  Yes

  

0.8 [0.4;1.1]c

  

  No

  

ref

  

 Experienced AIDS-related malignancies

  Yes

−1.8 [−2.6;-1.0]c

1.6 [0.6;2.7]b

   

  No

ref

ref

   

 HCV Co-infection

  Yes

−1.7 [−2.7;-0.7]c

  

0.6 [0.3;0.9]c

 

  No

ref

  

ref

 

Non-parametric portion of the model

 

EDF

EDF

EDF

EDF

EDF

 Cohort (year of diagnosis)

3.2b

2.2c

1.7

2.1

3.7c

 Age

1.1c

6.2c

7.7c

8.6c

1.4c

  1. Significance confidence level: a10%,b5% and c1%