Table 1 Study Matrix

1) Level of informed choice (derived from knowledge, attitudes, informed subscore of Decisional Conflict Scale).

2) Development of novel, personalised risk information materials.

3) Intention to take up an offer of colonoscopy.

Providing personalised risk information will provide individuals with truly informed choice based on their own risk level and improve satisfaction in screening participants.

• Age

• Gender

• SIMD

• Study arm

• Previous screening history

• Measures of informed choice:

 ° Knowledge

 ° Attitude

 ° Informed subscore (Decisional Conflict Scale)

• Behaviour (intention to uptake colonoscopy)

• Anxiety

Comparison of knowledge, attitudes and intention to uptake colonoscopy between the study arms.

Data on intention to take up colonoscopy from each scenario will be matched with the expected range of risk scores in the Scottish population.

Comparison of themes from the qualitative analysis between those who intended and did not intend to take up the offer of colonoscopy.

Any differences with respect to age/gender/

socioeconomic status and also whether or not previously participated in screening and/or taken up the offer of colonoscopy would also be explored.

Differences in intention to uptake colonoscopy between study arms will help to inform a full-scale RCT to evaluate uptake of colonoscopy in Scottish Bowel Screening Programme participants.