Outcomes
|
All-cause mortality
|
Cardiac mortality
|
---|
Models
|
HR (95% CI)
|
HR (95% CI)
|
---|
Model 1
|
RRF*age (≤59)
|
1.00(reference)
|
1.00(reference)
|
RRF*age (60–69)
|
0.46 (0.19–1.15)
|
0.50 (0.67–2.14)
|
RRF*age (≥70)
|
0.27 (0.12–0.61)
|
0.33 (0.11–0.97)
|
P for trend
|
0.003
|
0.048
|
Model 2
|
RRF*age (≤59)
|
1.00(reference)
|
1.00(reference)
|
RRF*age (60–69)
|
0.60 (0.23–1.54)
|
1.18 (0.34–4.16)
|
RRF*age (≥70)
|
0.32 (0.14–0.75)
|
0.48 (0.15–1.55)
|
P for trend
|
0.010
|
0.053
|
- Model 1 includes age group, RRF (eGFR < 60 ml/min/1.73 m2), and the interaction terms for them (RRF*age group)
- Model 2 includes age group, RRF (< 60 ml/min/1.73 m2), the interaction terms for them (RRF*age group), and further adjusted for gender, pre-hypertension, pre-diabetes mellitus, systolic blood pressure, Killip class, severity of CAD, diagnosis of ACS, treatment of PCI
- Abbreviations: RRF reduced renal function; eGFR estimated glomerular filtration rate, HR hazard ratio, CI confidence interval, CAD coronary artery disease, ACS acute coronary syndrome, PCI percutaneous coronary intervention