Skip to main content

Table 3 Hazard ratios for outcomes according to the interaction terms for age group and RRF

From: Influence of age on the effect of reduced renal function on outcomes in patients with coronary artery disease

Outcomes All-cause mortality Cardiac mortality
Models HR (95% CI) HR (95% CI)
Model 1
 RRF*age (≤59) 1.00(reference) 1.00(reference)
 RRF*age (60–69) 0.46 (0.19–1.15) 0.50 (0.67–2.14)
 RRF*age (≥70) 0.27 (0.12–0.61) 0.33 (0.11–0.97)
 P for trend 0.003 0.048
Model 2
 RRF*age (≤59) 1.00(reference) 1.00(reference)
 RRF*age (60–69) 0.60 (0.23–1.54) 1.18 (0.34–4.16)
 RRF*age (≥70) 0.32 (0.14–0.75) 0.48 (0.15–1.55)
 P for trend 0.010 0.053
  1. Model 1 includes age group, RRF (eGFR < 60 ml/min/1.73 m2), and the interaction terms for them (RRF*age group)
  2. Model 2 includes age group, RRF (< 60 ml/min/1.73 m2), the interaction terms for them (RRF*age group), and further adjusted for gender, pre-hypertension, pre-diabetes mellitus, systolic blood pressure, Killip class, severity of CAD, diagnosis of ACS, treatment of PCI
  3. Abbreviations: RRF reduced renal function; eGFR estimated glomerular filtration rate, HR hazard ratio, CI confidence interval, CAD coronary artery disease, ACS acute coronary syndrome, PCI percutaneous coronary intervention
\