Best-fitting life course models | Model 1 (adjusted for age + sex) | Model 2 (Model 1 + exposure to parental smoking) | Model 3 (Model 1 + intention to smoke in the following year) | ||
---|---|---|---|---|---|
RR (95% CI) | RR (95% CI) | Excess risk explained†, % | RR (95% CI) | Excess risk explained†, % | |
Sensitive period model | |||||
 Former smokers at CDAH-2§ | |||||
  Manual, baseline | 0.79 (0.63, 0.98) | 0.78 (0.63, 0.98) | −2.6 | 0.76 (0.60, 0.95) | −14.6 |
  Manual, CDAH-1 | 1.25 (0.93, 1.68) | 1.24 (0.93, 1.67) | 3.0 | 1.20 (0.89, 1.60) | 22.1 |
  Manual, CDAH-2 | 1.00 (0.73, 1.37) | 0.99 (0.72, 1.35) | > 100‡ | 0.97 (0.71, 1.33) | > 100‡ |
Current smokers at CDAH-2§ | |||||
 Manual, baseline | 1.32 (1.00, 1.73) | 1.21 (0.93, 1.58) | 33.0 | 1.19 (0.89, 1.59) | 40.2 |
 Manual, CDAH-1 | 1.42 (0.95, 2.11) | 1.43 (0.98, 2.10) | −3.4 | 1.24 (0.83, 1.86) | 42.3 |
 Manual, CDAH-2 | 1.55 (1.04, 2.30) | 1.42 (0.97, 2.09) | 23.0 | 1.50 (1.01, 2.25) | 7.8 |
Accumulation model, No. of times manual | |||||
 Former smokers at CDAH-2§ | 1.01 (0.91, 1.12) | 1.00 (0.90, 1.11) | > 100‡ | 0.97 (0.87, 1.07) | > 100‡ |
 Current smokers at CDAH-2§ | 1.43 (1.27, 1.61) | 1.36 (1.21, 1.53) | 16.0 | 1.32 (1.17, 1.48) | 20.6 |