Growth | Face | CNS | PAE | |
---|---|---|---|---|
FAS | Evidence of prenatal growth impairment, as in at least 1 of: - Birth weight/length ≤ 10th percentile for GA - Height/weight ≤ 10th percentile for age - Disproportionately low weight-height ratio (= 10th percentile) | Simultaneous presentation of all 3 sentinel facial features - Short palpebral fissure length (≤ 2 SD below mean) - Smooth or flattened philtrum (rank 4 or 5)a - Thin upper lip (rank 4 or 5)a | Evidence of impairment in ≥3 CNS domains: | Confirmed or unconfirmed PAE |
pFAS | – | Simultaneous presentation of 2 sentinel facial features (as above) | Impairment in ≥3 CNS domains | Confirmed PAE |
ARND | – | – | Impairment in ≥3 CNS domains | Confirmed PAE |